Results 131 to 140 of about 349,940 (358)

7‐Ketodeoxycholic Acid Promotes Colonic Mucosal Healing by Inducing Calcium Release from Endoplasmic Reticulum via the TGR5‐IP3R Pathway

open access: yesAdvanced Science, EarlyView.
7‐KDCA functions by driving intestinal epithelial cell migration through induction of calcium release from the endoplasmic reticulum. The findings emphasize a previously unrecognized property of 7‐KDCA in regulating cell migration, a required process for effective epithelial restitution and repair that is particularly critical for patients with UC to ...
Jing Zhang   +9 more
wiley   +1 more source

Constructing Dual‐Atomic Fe─Fe Sites Nanozyme for Targeted Osteoarthritis Therapy through Mitigating Oxidative Stress and Cartilage Degeneration

open access: yesAdvanced Science, EarlyView.
A novel bimetallic nanozyme (Fe2–NCs) with well‐defined Fe–Fe active sites is synthesized through a host–guest coordination strategy, which exhibits an exceptional therapeutic efficacy in osteoarthritis therapy. Experimental and theoretical analyses uncover the intrinsic catalytic mechanism at the atomic level, offering fundamental insights and design ...
Ting Ying   +6 more
wiley   +1 more source

Management of Child Feces: Current Disposal Practices [PDF]

open access: yes, 2015
This research brief examines how children's feces are disposed of, a neglected area of research, policy, and program intervention, and there is very little evidence of effective strategies for increasing the safe disposal of children's ...

core  

A Bacteriophage Feces Media

open access: yesExperimental Biology and Medicine, 1932
It became desirable in the course of some investigations to develop a media to determine the relative biological stability of fecal B. coli strains to bacteriophage. The relative sensitiveness of the B. coli flora can be altered by diet. The isolation of colonies and testing their phage-sensitiveness is too involved for practical purposes. We wished to
openaire   +2 more sources

Type 2 Diabetes‐Associated Phenylacetylglutamine Induces Deleterious Inflammation Cycle in Myeloid Cells through β2 Adrenergic Receptors and Impedes Wound Healing

open access: yesAdvanced Science, EarlyView.
The microbiota‐derived metabolite phenylacetylglutamine (PAGln) is elevated in type 2 diabetes and tightly associated with poor healing in both diabetic and non‐diabetic human patients. PAGln promotes mouse inflammation and impairs healing through a transmissible β2‐adrenergic receptor–mediated trained‐immunity loop.
Lu Huang   +12 more
wiley   +1 more source

Synergistic Promotion of Triple‐Negative Breast Cancer Tumorigenesis and Metastasis by Oral Polystyrene Nanoplastics Exposure via Alloprevotella‐Derived Glutamate and Platelet Activation

open access: yesAdvanced Science, EarlyView.
Polystyrene nanoplastics (PS‐NPs) administered via oral exposure accelerate triple‐negative breast cancer (TNBC) progression by synergistically modulating gut microbiota‐derived glutamate production and platelet activation. This study uncovers a pivotal crosstalk between microbial metabolites and platelet‐tumor interactions, offering mechanistic ...
Leilei Zhu   +9 more
wiley   +1 more source

Untargeted Metabolomics of Feces Reveals Diagnostic and Prognostic Biomarkers for Active Tuberculosis and Latent Tuberculosis Infection: Potential Application for Precise and Non-Invasive Identification

open access: yesInfection and Drug Resistance, 2023
Dan Luo,1,2,* Bo-Yi Yang,3,* Kai Qin,4 Chong-Yu Shi,3 Nian-Sa Wei,4 Hai Li,1 Yi-Xiang Qin,1 Gang Liu,1 Xiao-Ling Qin,1 Shi-Yi Chen,1 Xiao-Jing Guo,1 Li Gan,1 Ruo-Lan Xu,1 Bai-Qing Dong,1 Jing Li5 1Department of Biostatistics, School of Public ...
Luo D   +14 more
doaj  

Characteristics of vancomycin-resistant enterococci (VRE) isolated from medical fields in Japan [PDF]

open access: yes, 2018
学位記番号 ...
Hashimoto, Yusuke   +2 more
core  

Polydopamine Nanodots Ameliorate Inflammatory Bowel Disease by Restoring Redox Homeostasis and Intestinal Microenvironment

open access: yesAdvanced Science, EarlyView.
A novel melanin‐based therapeutic composed of ultrasmall polydopamine nanodots is employed as an efficient oral formulation for the targeted treatment of inflammatory bowel disease. The potential therapeutic mechanism of polydopamine nanodots mainly involves the elimination of excessive oxidative stress, the reduction of ROS‐mediated proinflammatory ...
Zhen Ding   +11 more
wiley   +1 more source

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