Results 41 to 50 of about 101,209 (306)
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Modelling of L-valine Repeated Fed-batch Fermentation Process Taking into Account the Dissolved Oxygen Tension [PDF]
Bioautomation, 2009 This article deals with synthesis of dynamic unstructured model of variable volume fed-batch fermentation process with intensive droppings for L-valine production.
Tzanko Georgiev +4 more
doaj
Microbial Cell Factories, 2020 Background Docosahexaenoic acid (DHA) is essential for human diet. However, high production cost of DHA using C. cohnii makes it currently less competitive commercially, which is mainly caused by low DHA productivity.
Liangsen Liu +7 more
doaj +1 more source
Iterative design of dynamic experiments in modeling for optimization of innovative bioprocesses [PDF]
, 2009 Finding optimal operating conditions fast with a scarce budget of experimental runs is a key problem to speed up the development and scaling up of innovative bioprocesses. In this paper, a novel iterative methodology for the model-based design of dynamic
Cristaldi, Mariano Daniel +2 more
core +1 more source
FEBS Open Bio, EarlyView.A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li +6 more
wiley +1 more source
Optimal Control of fed batch bioreactor
International Journal of Research in Advent Technology, 2021 In this paper, we will consider the problem of optimal control of a fed batch reactor. Our objective is to simulate the fed batch reactor under specified conditions in order to find an optimal control policy. Thus, for any specified initial conditions and parameter values the optimal policy for reactor operation can be obtained from simulation. We have
Durgesh Bonde, Dr. Satish Inamdar
openaire +1 more source
Repeated fed-batch cultivation of nitrogen-fixing bacterium, Bacillus sphaericus UPMB10, using glycerol as the carbon source [PDF]
, 2010 The exponential fed-batch cultivation of Bacillus sphaericus UPMB10 in 2 l stirred tank fermenter was performed by feeding the initial batch culture with 14 g l-1 of glycerol according to the algorithm aimed at controlling the specific growth rate (µ) of
Ariff, Arbakariya +3 more
core
Scaling-up vaccine production: implementation aspects of a biomass growth observer and controller [PDF]
, 2009 This study considers two aspects of the implementation of a biomass growth observer and specific growth rate controller in scale-up from small- to pilot-scale bioreactors towards a feasible bulk production process for whole-cell vaccine against whooping ...
Boxtel, A.J.B., van +4 more
core +2 more sources
Optimised production and extraction of astaxanthin from the yeast Xanthophyllomyces dendrorhous [PDF]
, 2020 Currently, astaxanthin demand is fulfilled by chemical synthesis using petroleum-based feedstocks. As such, alternative pathways of natural astaxanthin production attracts much research interest.
Charalampopoulos, Dimitris +3 more
core +1 more source
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source