Results 11 to 20 of about 11,099 (258)

Online automatic tuning and control for fed-batch cultivation [PDF]

open access: yesBioprocess and Biosystems Engineering, 2007
Performance of controllers applied in biotechnological production is often below expectation. Online automatic tuning has the capability to improve control performance by adjusting control parameters. This work presents automatic tuning approaches for model reference specific growth rate control during fed-batch cultivation.
Soons, Z.I.T.A.   +3 more
openaire   +4 more sources

Fed‐Batch Cultivation of Saccharomyces cerevisiae in a Hyperbaric Bioreactor [PDF]

open access: yesBiotechnology Progress, 2003
Abstract Fed‐batch is the dominating mode of operation in high‐cell‐density cultures of Saccharomyces cerevisae in processes such as the production of bakerapos;s yeast and recombinant proteins, where the high oxygen demand of these cultures makes its supply an important and
Belo, Isabel, Pinheiro, Rita, Mota, M.
openaire   +3 more sources

Repetitive Fed-Batch: A Promising Process Mode for Biomanufacturing With E. coli

open access: yesFrontiers in Bioengineering and Biotechnology, 2020
Recombinant protein production with Escherichia coli is usually carried out in fed-batch mode in industry. As set-up and cleaning of equipment are time- and cost-intensive, it would be economically and environmentally favorable to reduce the number of ...
Julian Kopp   +5 more
doaj   +1 more source

Effect of different fermentation strategies on Bacillus thuringiensis cultivation and its toxicity towards the bagworm, Metisa plana Walker (Lepidoptera: Psychidae)

open access: yesEgyptian Journal of Biological Pest Control, 2020
The effect of batch and fed-batch fermentation on the cultivation performance of Bacillus thuringiensis was investigated using a 5-l stirred tank bioreactor.
Mohamed Mazmira Mohd Masri   +1 more
doaj   +1 more source

Effect of Developed Low Cost Minimal Medium on Lipid and Exopolysaccharide Production by Lipomyces starkeyi Under Repeated Fed-batch and Continuous Cultivation [PDF]

open access: yesChemical and Biochemical Engineering Quarterly, 2019
The main objective of this study was to investigate the effects of a low cost minimal medium, developed by the UL Bioprocessing Lab, on the cultivation of Lipomyces starkeyi NRRL Y-11557 using repeated fed-batch and continuous fermentation strategies ...
V. Thirumal   +5 more
doaj   +1 more source

Optimized polymer-based glucose release in microtiter plates for small-scale E. coli fed-batch cultivations

open access: yesJournal of Biological Engineering, 2020
Background Small-scale cultivation vessels, which allow fed-batch operation mode, become more and more important for fast and reliable early process development.
Timm Keil   +3 more
doaj   +1 more source

High cell density cultivation of E. coli in shake flasks for the production of recombinant proteins

open access: yesBiotechnology Reports, 2022
Batch cultivation of recombinant bacteria in shake flasks typically results in low cell density due to nutrient depletion. Previous studies on high cell density cultivation in shake flasks have relied mainly on controlled release mechanisms.
Snehal D Ganjave   +4 more
doaj   +1 more source

Functional State Modelling of Cultivation Processes: Dissolved Oxygen Limitation State [PDF]

open access: yesInternational Journal Bioautomation, 2015
A new functional state, namely dissolved oxygen limitation state for both bacteria Escherichia coli and yeast Saccharomyces cerevisiae fed-batch cultivation processes is presented in this study.
Olympia Roeva   +3 more
doaj   +2 more sources

Repeated fed-batch strategy and metabolomic analysis to achieve high docosahexaenoic acid productivity in Crypthecodinium cohnii

open access: yesMicrobial Cell Factories, 2020
Background Docosahexaenoic acid (DHA) is essential for human diet. However, high production cost of DHA using C. cohnii makes it currently less competitive commercially, which is mainly caused by low DHA productivity.
Liangsen Liu   +7 more
doaj   +1 more source

Enhancement of co-production of lutein and protein in Chlorella sorokiniana FZU60 using different bioprocess operation strategies

open access: yesBioresources and Bioprocessing, 2021
Co-production of multiple compounds is an efficient approach to enhance the economic feasibility of microalgae-based metabolites production. In this study, Chlorella sorokiniana FZU60 was cultivated under different bioprocess strategies to enhance the co-
Ruijuan Ma   +7 more
doaj   +1 more source

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