Results 11 to 20 of about 11,099 (258)
Online automatic tuning and control for fed-batch cultivation [PDF]
Performance of controllers applied in biotechnological production is often below expectation. Online automatic tuning has the capability to improve control performance by adjusting control parameters. This work presents automatic tuning approaches for model reference specific growth rate control during fed-batch cultivation.
Soons, Z.I.T.A. +3 more
openaire +4 more sources
Fed‐Batch Cultivation of Saccharomyces cerevisiae in a Hyperbaric Bioreactor [PDF]
Abstract Fed‐batch is the dominating mode of operation in high‐cell‐density cultures of Saccharomyces cerevisae in processes such as the production of bakerapos;s yeast and recombinant proteins, where the high oxygen demand of these cultures makes its supply an important and
Belo, Isabel, Pinheiro, Rita, Mota, M.
openaire +3 more sources
Repetitive Fed-Batch: A Promising Process Mode for Biomanufacturing With E. coli
Recombinant protein production with Escherichia coli is usually carried out in fed-batch mode in industry. As set-up and cleaning of equipment are time- and cost-intensive, it would be economically and environmentally favorable to reduce the number of ...
Julian Kopp +5 more
doaj +1 more source
The effect of batch and fed-batch fermentation on the cultivation performance of Bacillus thuringiensis was investigated using a 5-l stirred tank bioreactor.
Mohamed Mazmira Mohd Masri +1 more
doaj +1 more source
Effect of Developed Low Cost Minimal Medium on Lipid and Exopolysaccharide Production by Lipomyces starkeyi Under Repeated Fed-batch and Continuous Cultivation [PDF]
The main objective of this study was to investigate the effects of a low cost minimal medium, developed by the UL Bioprocessing Lab, on the cultivation of Lipomyces starkeyi NRRL Y-11557 using repeated fed-batch and continuous fermentation strategies ...
V. Thirumal +5 more
doaj +1 more source
Background Small-scale cultivation vessels, which allow fed-batch operation mode, become more and more important for fast and reliable early process development.
Timm Keil +3 more
doaj +1 more source
High cell density cultivation of E. coli in shake flasks for the production of recombinant proteins
Batch cultivation of recombinant bacteria in shake flasks typically results in low cell density due to nutrient depletion. Previous studies on high cell density cultivation in shake flasks have relied mainly on controlled release mechanisms.
Snehal D Ganjave +4 more
doaj +1 more source
Functional State Modelling of Cultivation Processes: Dissolved Oxygen Limitation State [PDF]
A new functional state, namely dissolved oxygen limitation state for both bacteria Escherichia coli and yeast Saccharomyces cerevisiae fed-batch cultivation processes is presented in this study.
Olympia Roeva +3 more
doaj +2 more sources
Background Docosahexaenoic acid (DHA) is essential for human diet. However, high production cost of DHA using C. cohnii makes it currently less competitive commercially, which is mainly caused by low DHA productivity.
Liangsen Liu +7 more
doaj +1 more source
Co-production of multiple compounds is an efficient approach to enhance the economic feasibility of microalgae-based metabolites production. In this study, Chlorella sorokiniana FZU60 was cultivated under different bioprocess strategies to enhance the co-
Ruijuan Ma +7 more
doaj +1 more source

