Results 21 to 30 of about 11,099 (258)

Strategies for Automated Control of the Bioproduction of Mcl-PHA Biopolymers [PDF]

Chemical and Biochemical Engineering Quarterly, 2017
Medium-chain-length polyhydroxyalkanoates (mcl-PHAs) are polyesters synthesized by numerous bacteria as storage material. Despite being promising candidates for biodegradable materials of industrial interest and environmental value, their usage is ...
P. Hrnčiřík, J. Náhlík, J. Mareš
doaj   +1 more source

Systematic evaluation of characteristics of the membrane-based fed-batch shake flask

Microbial Cell Factories, 2017
Background The initial part of process development involves extensive screening programs to identify optimal biological systems and cultivation conditions.
P. Philip, K. Meier, D. Kern, J. Goldmanns, F. Stockmeier, C. Bähr, J. Büchs   +6 more
doaj   +1 more source

Improved microscale cultivation of Pichia pastoris for clonal screening

Fungal Biology and Biotechnology, 2018
Background Expanding the application of technical enzymes, e.g., in industry and agriculture, commands the acceleration and cost-reduction of bioprocess development.
Alexander Eck, Matthias Schmidt, Stefanie Hamer, Anna Joelle Ruff, Jan Förster, Ulrich Schwaneberg, Lars M. Blank, Wolfgang Wiechert, Marco Oldiges   +8 more
doaj   +1 more source

Comparison Between Simple Batch and Fed-Batch Bioreactor Cultivation of Recombinant BCG

Pharmaceutics
Background/Objectives: Tuberculosis continues to be a significant global health concern, causing 1.3 million deaths in 2022, particularly affecting children under 5 years old.
Sarah Mendes, Maria C. P. Gonçalves, Vitoria A. P. Aiex, Ryhára D. Batista, Patrícia Zorzete, Luciana C. C. Leite, Viviane M. Gonçalves   +6 more
doaj   +1 more source

Strategies for improving production performance of probiotic Pediococcus acidilactici viable cell by overcoming lactic acid inhibition

AMB Express, 2017
Lactic acid bacteria are industrially important microorganisms recognized for fermentative ability mostly in their probiotic benefits as well as lactic acid production for various applications.
Majdiah Othman, Arbakariya B. Ariff, Helmi Wasoh, Mohd Rizal Kapri, Murni Halim   +4 more
doaj   +1 more source

Model Predictive Control—A Stand Out among Competitors for Fed-Batch Fermentation Improvement

Fermentation, 2023
The fed-batch cultivation is in many ways a benchmark for fermentation processes, and it has been an attractive choice for the biotechnological production of various products in the past decades.
Emils Bolmanis, Konstantins Dubencovs, Arturs Suleiko, Juris Vanags   +3 more
doaj   +1 more source

Effects of Caprolactam Wastewater on Algal Growth and Nutrients Removal by Arthrospira platensis

Applied Sciences, 2021
Caprolactam wastewater (WCP), which is generated during the production of caprolactam, contains high contents of NO3− and inorganic P and is considered to be difficult to treat.
Youzhi Yu, Xu Li, Zhongjie Wang, Junfeng Rong, Kaixuan Wang, Yan Huo, Yahong Geng, Yeguang Li, Xiaobin Wen   +8 more
doaj   +1 more source

A Chemical Framework for Engineering Extracellular Vesicles’ Biointerface to Advance Precision Therapeutics

Advanced Materials, EarlyView.
Extracellular vesicles (EVs) are cell‐derived nanoparticles that mediate intercellular communication through their dynamic biointerfaces. Owing to their intrinsic biological functions, EVs have emerged as promising platforms for biomedical applications.
Leila Pourtalebi Jahromi, Felix Geng, Jan‐Noël Frenzke, Gregor Fuhrmann   +3 more
wiley   +1 more source

Extrusion Bioprinting for Wound Healing: Innovations in Functionalized Bioinks and Bioprinting Technology

Advanced Materials Technologies, EarlyView.
Extrusion‐based bioprinting (EBB) has emerged as a versatile biofabrication platform capable of precisely depositing bioinks composed of biomaterials, cells, and bioactive agents to generate patient‐specific, biomimetic skin constructs. This paper presents a state‐of‐the‐art and forward‐looking overview of EBB for wound healing, encompassing printing ...
Hien‐Phuong Le, Anh Tuan Trong Tran, Ammara Waheed, Tran Thanh Tung, Dusan Losic   +4 more
wiley   +1 more source

Enhancing Sustainability and Productivity in Komagataella phaffii Fermentation: A Techno-Economic Comparison of Fed-Batch and Continuous Cultivation with Mixed Induction Strategies

Fermentation
The increasing demand for recombinant proteins has driven innovation in bioprocessing strategies using Komagataella phaffii as a host organism. Conventional fed-batch cultivation with pure methanol induction remains widely used but presents challenges ...
Almir Yamanie, Salomé de Sá Magalhães, Acep Riza Wijayadikusumah, Neni Nurainy, Eli Keshavarz-Moore   +4 more
doaj   +1 more source