Results 211 to 220 of about 19,074 (293)

High-Yield Expression of Arylmalonate Decarboxylase in Escherichia coli Through High-Cell-Density Cultivation Strategies. [PDF]

Chembiochem
Gerstenberger J, Werbilo T, Kourist R, Kara S.   +3 more
europepmc   +1 more source

Controlled Feeding Facilitates the Development of a Robust Production Process for Terpolymeric Polyhydroxyalkanoates

Biotechnology Journal, Volume 21, Issue 6, June 2026.
Graphical Abstract and Lay Summary Cupriavidus necator NCIMB 11599 was cultivated with a fully automated pH–pO2‑dependent feeding strategy that enables controlled levulinic acid delivery and robust production of PHBVV terpolymer. The process was successfully transferred from 7.5 to 42‑L stirred‑tank reactors, maintaining PHA contents of ∼75% CDW and ...
Birk Achenbach, Pravesh Tamang, Steven Leonhardt, Günter E. M. Tovar, Susanne Zibek   +4 more
wiley   +1 more source

Antibiotic-Free Expression of γ-Glutamyl Transpeptidase in <i>Bacillus subtilis</i> and Process Optimization for L-Theanine Separation and Purification. [PDF]

Molecules
Zhang R, Jiang B, Xiao Z, Xiang L.
europepmc   +1 more source

Osmolality‐Independent Impact of Sodium on Glycosylation of an Fc‐Fusion Protein and the Hexosamine Biosynthesis Pathway in a Chinese Hamster Ovary Cell Line

Biotechnology Journal, Volume 21, Issue 6, June 2026.
Graphical Abstract and Lay Summary Sodium and potassium supplementation in CHO batch culture elevates intracellular UDP‐HexNAc concentrations through activation of the hexosamine biosynthesis pathway (HBP), independently of osmolality. Increased nucleotide sugar availability enhances Fc‐fusion protein glycosylation and reduces the abundance of low ...
Jason Reiniger, Adrian Pöttner, Lara Rosenberger, Aline Zimmer   +3 more
wiley   +1 more source

An integrated cell and medium engineering approach for production of a nanobody fusion in Saccharomyces cerevisiae. [PDF]

Appl Microbiol Biotechnol
Niemelä LRK, Kirjavainen LM, Kozlowski HCJ, Salminen H, Frey AD.   +4 more
europepmc   +1 more source

Severe Restriction of Glucose Import Enhances Recombinant Protein Production in Escherichia coli

Biotechnology Journal, Volume 21, Issue 6, June 2026.
Graphical Abstract and Lay Summary Producing recombinant proteins in Escherichia coli is often limited by the bacterium's tendency to consume glucose too rapidly. This excessive glucose uptake causes overflow metabolism, leading to the accumulation of acetate, a byproduct that can reduce cellular performance and protein production.
Juan Carlos Fragoso‐Jiménez, Juan Carlos Sigala, Frank Delvigne, Alfredo Martínez, Alvaro R. Lara, Guillermo Gosset   +5 more
wiley   +1 more source

Engineering of Corynebacterium glutamicum for the enhanced production of optically pure (meso)-2,3-butanediol. [PDF]

Bioresour Bioprocess
Song ES, Kim KH, Lee JY, Jeong KJ.
europepmc   +1 more source

Transfer Learning Approaches in Bioprocess Engineering: Opportunities and Challenges

Biotechnology and Bioengineering, Volume 123, Issue 6, Page 1417-1431, June 2026.
ABSTRACT Transfer learning (TL) has recently emerged as a promising approach to overcoming one of the key limitations of bioprocess engineering: data scarcity. By leveraging knowledge from one bioprocess to another, TL allows existing models and data sets to be reused efficiently, accelerating process development, improving prediction accuracy, and ...
Daniel Barón Díaz, Anna‐Lena Drommershausen, Alexander Grünberger, Dirk Holtmann   +3 more
wiley   +1 more source

From beet molasses to malic acid: holistic development of fermentation and downstream process. [PDF]

Biotechnol Biofuels Bioprod
Grebe LA, Krekel CM, Maaß CA, Beckers M, Smotrycki M, Phan ANT, Blank LM, Saur K, Mann M, Viell J, Jupke A, Magnus JB.   +11 more
europepmc   +1 more source

All You Can Eat Yeast: Substituting Hexose Transporters With AtSWEET7 Alleviates Glucose Repression, Enabling Simultaneous Utilization of Sugars in Renewable Feedstocks

Biotechnology and Bioengineering, Volume 123, Issue 6, Page 1518-1530, June 2026.
ABSTRACT Yeast sugar transporters have highly evolved for preferential glucose transport, a significant roadblock for utilizing non‐glucose sugars in renewable feedstocks such as lignocellulosic biomass. To enable simultaneous transport of multiple sugars, native hexose transporters were replaced by SWEET7p from Arabidopsis thaliana in engineered ...
Nurzhan Kuanyshev, Degaulle Dai, Jungyeon Kim, Nam Kyu Kang, Ming‐Hsun Cheng, Vijay Singh, Yong‐Su Jin   +6 more
wiley   +1 more source