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Designing new controller for fed-batch cultivation of recombinant E.coli

2008 27th Chinese Control Conference, 2008
Fed-batch fermentation processes are common methods of producing biologic recombinant cells from different microorganisms. Model-based control of bioprocesses is a difficult task due to the challenges associated with bioprocess modelling and the lack of on-line measurements.
Mohseni Saleh   +2 more
openaire   +1 more source

Grey-box stochastic modelling of industrial fed-batch cultivation

2006
Abstract This paper presents application of a grey-box stochastic modelling framework for developing continuous time models for dynamic systems based on experimental data. The framework is used to develop predictive models suited for control purposes.
Jan K. Rasmussen   +2 more
openaire   +1 more source

Fed-Batch Cultivation Control Based on Genetic Algorithm PID Controller Tuning

2011
In this paper a universal discrete PID controller for the control of E. coli fed-batch cultivation processes is designed. The controller is used to control feed rate and to maintain glucose concentration at the desired set point. Tuning the PID controller, to achieve good closed-loop system performance, using genetic algorithms is proposed. As a result
Olympia Roeva, Tsonyo Slavov
openaire   +1 more source

Fed-batch addition of urea for Spirulina platensis cultivation

Enzyme and Microbial Technology, 2003
Paolo Torre   +5 more
openaire   +1 more source

Arthrospira platensis cultivation by fed-batch feeding of ammonium and urea

2009
This work deals with the cultivation in a tubular photobioreactor of the cyanobacterium Arthrospira platensis by fed-batch pulse-feeding a medium where the traditional nitrogen source (nitrate) was substituted by cheaper sources (ammonium and urea) at increasing inlet concentration.
LODI, ALESSANDRA   +4 more
openaire   +1 more source

Fed-Batch Cultivation in Baffled Shake Flasks

Genetic Engineering & Biotechnology News, 2011
openaire   +1 more source

Optimization of Synthetic Media Composition for Kluyveromyces marxianus Fed-Batch Cultivation

Fermentation, 2021
Jänis Liepinš   +2 more
exaly  

Simple fed-batch technique for high cell density cultivation of Escherichia coli

Journal of Biotechnology, 1995
Ursula Rinas, W -D Deckwer
exaly  

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