Results 221 to 230 of about 11,099 (258)
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Construction and fed-batch cultivation of Candida famata with enhanced riboflavin production
Journal of Biotechnology, 2014Riboflavin (vitamin B2) is an essential nutrition component serving as a precursor of coenzymes FMN and FAD that are involved mostly in reactions of oxidative metabolism. Riboflavin is produced in commercial scale and is used in feed and food industries, and in medicine.
Kostyantyn, Dmytruk +6 more
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Fed-Batch cultivation ofSaccharomyces cerevisiae with increased content of Δ5,7-sterols
Folia Microbiologica, 1986Cultivation of Saccharomyces cerevisiae with a linear nutrient feed was used to test the validity of a mathematical model describing changes in the physiological state of the culture. Markers of these changes were the concentrations of proteins and delta 5,7-sterols in yeast dry mass.
B, Bĕhalová +3 more
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Evaluation of mammalian fed-batch cultivations by two different models
Bioprocess Engineering, 1997Simulations of fed-batch hybridoma cell cultures were performed with two different models, a new model suggested by Nielsen and an older model suggested by Batt and Kompala. The response of the new Nielsen model was less sensitive to changes in feed concentrations and frequencies than the Batt and Kompala model.
A. Ryszczuk, C. Emborg
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Genetic Algorithms Based Parameter Identification of Yeast Fed-Batch Cultivation
2011Different kinds of genetic algorithms have been investigated for a parameter identification of a fermentation process. Altogether eight realizations of genetic algorithms have been presented - four of simple genetic algorithms and four of multi-population ones.
Maria Angelova +2 more
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EXPERIMENTAL INVESTIGATION OF DATADRIVEN MODELLING FOR CONTROL OF FED-BATCH CULTIVATION
IFAC Proceedings Volumes, 2005Abstract Application of the data driven modelling framework entitled Grid of Linear Models to derive a predictive model for a fed-batch fermentation process is presented. The modelling framework utilises a large number of local linear models to approximate the behaviour of the non-linear process. Industrial data from a fed-batch fermentation has been
Jan Kamyno Rasmussen +1 more
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A Guide to Fed-Batch Cultivation of Pichia pastoris on Laboratory Scale
Fed-batch is the most commonly used cultivation mode for industrial production of recombinant proteins with Pichia pastoris. On a laboratory scale, fed-batch culture provides a way to control the specific biomass growth rates at any pre-set value, allowing the conditions of biomass growth and recombinant product formation to be systematically studied ...Marcel, Straumann +4 more
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The Hagen–Poiseuille pump for parallel fed-batch cultivations in microbioreactors
Chemical Engineering Science, 2009Abstract We developed and applied a micropump for liquid flows of 0–150 nL/min. The operating principle of this pump is based on the Hagen–Poiseuille law. The main advantages of this pump are that an accurate continuous flow rate can be achieved, it is cheap to manufacture, easy to parallelize and easy to integrate in microtiter plates.
Michiel van Leeuwen +5 more
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Control of Fed-Batch Yeast Cultivation Using a Capacitance Sensor
2009Abstract Saccharomyces cerevisiae biomass is still one of the most important biotechnological products in the world, mainly in the form of baker's yeast. Costs of substrates have an important position in the overall economics of baker's yeast production, which is usually run in fed-batch bioreactors.
Giann B. Reis +4 more
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Yield Improvements Utilising Fed-Batch Cultivation and Optimisation Strategies
1998In previous work, we have demonstrated the improvements that fed-batch systems can bring to the overall antibody productivity and antibody concentration obtained in batch culture.
C. S. Sanderson +2 more
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Recombinant streptokinase production by fed-batch cultivation of Escherichia coli
Enzyme and Microbial Technology, 1999Abstract Streptokinase (SK) is a specific effective medicine for thrombolytic therapy of acute myocardial infarction. This study established a process for the pilot production of recombinant streptokinase (r-SK). Engineering bacteria were fermented in a 20-l fermentor to produce r-SK. After simple renaturation and purification, 12.9 g of r-SK with 97.
Xue-Wu Zhang +5 more
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