Results 141 to 150 of about 53,182 (300)

Cholesterol‐Mediated Metabolic‐mechanotransductive Crosstalk Orchestrates Castration Resistance in Prostate Cancer

Advanced Science, EarlyView.
Full androgen deprivation (FAD) induces paracrine cholesterol in prostate cancer that drives the polarization of cancer‐associated fibroblasts (CAFs) and subsequent elevated matrix stiffness. Matrix stiffness in turn potentiates tumor cell survival under FAD pressure via dual mechanotransductive activation of the IRE1α‐XBP1s stress‐response axis ...
Shaojie Liu, Chao Xu, Jun Jiang, Limin He, Yike Zhou, Zhengxuan Li, Yu Li, Keying Zhang, Fa Yang, Tong Lu, Hongtao Song, Hai Zhu, Zhihao Hu, Xiaolong Zhao, Kai Gan, Hongji Li, Bo Yang, Rui Zhang, Weihong Wen, Donghui Han, Weijun Qin   +20 more
wiley   +1 more source

A Single‐Cell Transcriptomic Atlas of the Ovine Rumen Microbiome Characterizes Lineage‐Specific Metabolic Shifts Associated with Host Heat Tolerance

Advanced Science, EarlyView.
An optimized single‐cell transcriptomic framework profiles over 60 000 cells to map the ovine rumen microbiome, partitioning the ecosystem into seven cross‐species functional clusters. In heat‐resistant hosts, a lineage‐specific metabolic shift in Anaerovibrio lipolyticus toward a highly glycolytic phenotype contributes to a “nutritional sparing ...
Sanbao Zhang, Qinyang Jiang, Junjie Ma, Jianwei Zou, Fan Wang, Feifei Lv, Yanna Huang, Yongcheng Wang, Ziye Xu   +8 more
wiley   +1 more source

Pre-stage perfusion and ultra-high seeding cell density in CHO fed-batch culture: a case study for process intensification guided by systems biotechnology. [PDF]

Bioprocess Biosyst Eng, 2020
Stepper L, Filser FA, Fischer S, Schaub J, Gorr I, Voges R.   +5 more
europepmc   +1 more source

Fed-batch Culture of Aeromonas hydrophila for the production of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) using two carbon sources

, 1999
To produce polyhydroxyalkanoate (PHA) copolymer which consists of 3-hydroxybutyrate (3HB) and 3-hydroxyhexanoate (3HHx) by cultivation of Aeromonas hydrophila, fed-batch cultures were done under several nutrient limiting conditions. With the results from
Lee, Young, Lee, Seung Hwan, Lee, Sang Yup   +2 more
core   +1 more source

Wood‐Based Bioelectronics: Lignosulfonate‐Based Conductive Biocomposites for Paper Organic Electrochemical Transistors

Advanced Electronic Materials, EarlyView.
Biodegradable wood‐based bioelectronics are realized by integrating poly (2,3‐ethylenedioxythiopene:lignosulfonate (PEDOT:LigS) as a mixed ionicelectronic channel in organic electrochemical transistors fabricated on paper substrates. The biocomposite exhibits high conductivity, biocompatibility, and strong transistor performance, while devices built on
Katharina Matura, Tobias Grabner, Sarka Hradilova, Munise Cobet, Ariana Opletalova, Katerina Polakova, Alessandra Operamolla, Niyazi Serdar Sariciftci, Serpil Tekoglu   +8 more
wiley   +1 more source

Efficient production of unspecific Peroxygenases using continuous culture of Komagataella phaffii

Chemical Engineering Journal Advances
Unspecific peroxygenases (UPO) utilize hydrogen peroxide as cosubstrate and catalyze a broad range of selective oxidation reactions, offering advantages over complex and costly cytochromes P450 systems.
Zhiang Ma, Min Chen, Wuyuan Zhang, Jianye Xia   +3 more
doaj   +1 more source

Improved Production of Bacillus thuringiensis by Intermittent Fed-Batch Culture with Total Cell Retention

, 2010
Intermittent fed-batch culture with total cell retention was evaluated during Bacillus thuringiensis serovar. kurstaki fermentations aiming to enhance biomass and spore concentration yields while maintaining toxicity.
Edwin Habeych, Alexandre Restrepo-Boland, Andrés F González Barrios, Sergio Orduz   +3 more
core   +1 more source

Traceability of Agri‐Food Products: The Key to Conscious Trade

Agribusiness, EarlyView.
ABSTRACT Globalization and growing concerns about sustainability have led to improvements in product traceability, quality, and sustainability. Traceability contributes to environmental protection and supports sustainable development by fostering transparency in agricultural practices and encouraging the responsible use of resources.
Scarlett Queen Almeida Bispo, Fernanda Aparecida Silva, Michelle Márcia Viana Martins, Marcelo José Braga Nonnenberg, Ruan da Silva Vianna, Carla Cristina Passos Cruz   +5 more
wiley   +1 more source

Matrices (re)loaded: Durability, viability, and fermentative capacity of yeast encapsulated in beads of different composition during long-term fed-batch culture. [PDF]

Biotechnol Prog, 2020
Gulli J, Yunker P, Rosenzweig F.
europepmc   +1 more source

Potential of fed-batch culture in solid state fermentation for production of gibberellic acid.

, 1987
Fed-batch culture technique, applied to the solid state fermentation process for the production of gibberellic acid, improves the yield by 18.2% as compared to a conventional batch solid state ...
Lonsane, B. K., Kumar, P. K. R.
core