Results 271 to 280 of about 111,815 (303)

Fed-Batch Culture Development Based on Biomass Monitoring

1998
The glucose concentration in the growth medium influences specific glucose consumption rate; however, a glucose limitation well below 1.1 mM is needed to modify the specific growth rate or the lactate production rate; the limitation of lactate production could be interesting to facilitate scaling up of the production, as far as pH control is concerned.
Eric de Buyl, Alan Maxwell, Luc Fabry
openaire   +1 more source

Fed-Batch CHO Cell Culture for Lab-Scale Antibody Production

2017
Fed-batch culture is the most commonly used upstream process in industry today for recombinant monoclonal antibody production using Chinese hamster ovary (CHO) cells. Developing and optimizing this process in the lab is crucial for establishing process knowledge, which enables rapid and predictable tech-transfer to manufacturing scale. In this chapter,
Yuzhou, Fan, Daniel, Ley, Mikael Rørdam, Andersen   +2 more
openaire   +2 more sources

[Preparation of fed-batch culture of Nocardioides sp].

Prikladnaia biokhimiia i mikrobiologiia, 2003
A screening for carbon sources revealed ethanol to be the best substrate for condensed Nocardioides sp. culture. A strategy achieving the maximum (21 g/l) yield of biomass was developed for the control over the condensed fed-batch culture production. This control based on the algorithm ExpoDense should be predetermined in the first phase and adaptive ...
V M, Anan'in, V V, Fokina, G V, Sukhodol'skaia, M V, Donova   +3 more
openaire   +1 more source

Optimization of Fed-Batch Mammalian Cell Culture Processes

1994
Fed-batch cultures of hybridoma cells in a serum free medium were carried out in a computer controlled bioreactor. Oxygen uptake rate (OUR) and base addition for controlling pH were employed to calculate key physiologically related variables. Using established stoichiometric relationships between measured variables and the physiological demand we were ...
W. Zhou, W.-S. Hu
openaire   +1 more source

ANALYSIS OF FED‐BATCH MICROBIAL CULTURE

Annals of the New York Academy of Sciences, 1979
I. J. Dunn, S. Shioya, R. Keller
openaire   +1 more source

Maximization of metabolite in fed-batch cultures

Biochemical Engineering Journal, 2007
Hwa Sung Shin, Henry C. Lim
openaire   +1 more source

Improving fed-batch culture efficiency of Rhodiola sachalinensis cells and optimizing flash extraction process of polysaccharides from the cultured cells by BBD–RSM

Industrial Crops and Products, 2023
Mei-Lan Lian
exaly  

FED‐BATCH CULTURE OF MICROBES

Annals of the New York Academy of Sciences, 1979
openaire   +1 more source

Fed-batch Strategies for Mammalian Cell Cultures

1994
W. Noe, P. Schorn, R. Bux, W. Berthold
openaire   +1 more source

Using Alternating Tangential Flow with Fed-Batch Cultures

Genetic Engineering & Biotechnology News, 2019
Shashi Kudugunti, Daniel Diggins, Jyoti Amatya, Jamie Peyser   +3 more
openaire   +1 more source