Results 191 to 200 of about 304,733 (308)

An adaptive, continuous substrate feeding strategy based on evolved gas to improve fed-batch ethanol fermentation. [PDF]

Appl Microbiol Biotechnol
Hung YR, Sauvageau D, Bressler DC.
europepmc   +1 more source

Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy

Advanced Science, EarlyView.
Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu, Mengtao Sun, Lusheng Li, Jieqiong Wang, Shibiao Wan   +4 more
wiley   +1 more source

Scalable Manufacturing of Roll‐to‐Roll Slot‐Die Coated Perovskite Solar Cells

Advanced Science, EarlyView.
Roll‐to‐roll (R2R) slot‐die coating is emerging as a scalable pathway for perovskite solar cells. This mini‐review summarizes advances in ink design, drying control, and electrode integration that enable high‐efficiency flexible devices and modules. Challenges in throughput, stability, and sustainable processing are outlined, guiding the translation of
Farshad Jafarzadeh, MirKazem Omrani, Nathan S. Hill, Jazib Ali, Dumitru Sirbu, David G. Lidzey   +5 more
wiley   +1 more source

Model-based fed-batch cultivation of Viola odorata plant cells exhibiting antimalarial and anticancer activity. [PDF]

Front Bioeng Biotechnol
Babu R, Veeramani M, Aadinath W, Muthuvijayan V, Singh S, Srivastava S.   +5 more
europepmc   +1 more source

AI‐Assisted Self‐Powered Wearable Dual‐Mode Sensor With TENG and Stretchable Optical Fiber for Neurological Disorder Diagnostics

Advanced Science, EarlyView.
This manuscript presents the WDMS platform, an AI‐assisted, self‐powered wearable dual‐mode sensor for tele‐neurology. It integrates a contact–separation TENG insole with stretchable polyurethane optical‐fiber strain sensors to synchronously track plantar pressure and lower‐limb muscle deformation.
Tianliang Li, Han Liu, Guoxu Liu, Qian'ao Wang, Haotian Zhou, Guiyi Liu, Yan Xu, Jun Wang, Zuqiang Wang, Feng Zhu, Feiling Luo, Zhong Lin Wang, Chi Zhang   +12 more
wiley   +1 more source

Sertoli Cell‐Derived Extracellular Vesicles Orchestrate Cadmium‐Induced Testicular Inflammation and Fibrosis

Advanced Science, EarlyView.
Environmental cadmium exposure disrupts testicular homeostasis through a novel intercellular communication axis. Stressed Sertoli cells release extracellular vesicles carrying damage‐associated molecular patterns and mitochondrial fragments, which activate macrophages via TLR4/NF‐κB signaling.
Jianfeng Ma, Mailin Gan, Shuang Liang, Siyu Chen, Ziling Hao, Yiting Yang, Jiawei Lu, Qihang Wu, Yuqian Shi, Lijun Sun, Jiaxin Li, Saihao Wang, Yan Wang, Xiaofeng Zhou, Lei Chen, Ye Zhao, Li Zhu, Linyuan Shen   +17 more
wiley   +1 more source

Proteomics Reveals Distinctive Host Cell Protein Expression Patterns in Fed-Batch and Perfusion Cell Culture Processes. [PDF]

Biotechnol J
Sahoo A, Tsukiadate T, Lin BR, Kotzbauer E, Houser J, Patel M, Li X, Madabhushi SR.   +7 more
europepmc   +1 more source

Reinforcing Calcium Overload via Inflammation‐Mediated Targeting to Amplify Pyroptosis and Antitumor Immunity

Advanced Science, EarlyView.
A neutrophil‐membrane‐camouflaged nanoplatform (RC@NMVs) exploits tumor inflammation to target and accumulate in tumors. Intracellular Ca2+ overload is triggered via lysosomal CaP dissolution and Ru red‐mediated Ca2+ channel blockade, synergistically inducing gasdermin‐mediated pyroptosis.
Yingying Liu, Yang Liu, Qin Fan, Jinqiao Zhang, Kexin Wen, Boyu Yuan, Xianzhou Cai, Ziliang Dong, Lianhui Wang   +8 more
wiley   +1 more source

Incorporating shaken 24-deep-well plate fed-batch culture shortens CHO cell line development time. [PDF]

Cytotechnology
Ohira S, Omasa T.
europepmc   +1 more source

Detachment‐Induced FAK‐STAT3‐NNMT Inhibits CTCs Anoikis to Promote Breast Cancer Metastasis by Enhancing Fatty Acid Oxidation

Advanced Science, EarlyView.
The FAK‐STAT3‐NNMT axis drives anoikis resistance in circulating tumor cells by reprogramming fatty acid oxidation. Targeting this metabolic vulnerability suppresses metastasis, untangling a key mechanism of breast cancer progression and revealing NNMT as a promising therapeutic target.
Qingchao Tong, Yilei Ma, Yuzhen Gao, Lin Zhou, Luping Lou, Qiang Fang, Sining Fang, Ru Zhao, Jin Zeng, Jun Yang, Guoli Li, Xinyou Xie, Yanzhong Wang, Jun Zhang   +13 more
wiley   +1 more source