Results 211 to 220 of about 75,010 (260)

Fed-batch cultivation of Wautersia eutropha

Bioresource Technology, 2008
Batch kinetics of polyhydroxybutyrate (PHB) synthesis in a bioreactor under controlled conditions of pH and dissolved oxygen gave a biomass of 14 g l(-1) with a PHB concentration of 6.1 g l(-1) in 60 h. The data of the batch kinetics was used to develop a mathematical model, which was then extrapolated to fed-batch by incorporating the dilution due to ...
Ashok Srivastava
exaly   +3 more sources

Fed-batch bioproduction of spectinomycin

2007
Actinomycetes produce about 67% of the known antibiotics covering a wide range of chemical structures. However, their filamentous growth present several problems during industrial processes. Among these problems oxygen transfer limitation is critical.
J, Gomes, A S, Menawat
openaire   +2 more sources

Feed Optimization in Fed-Batch Culture

2013
Fed-batch processes are a current preference for the production of recombinant proteins in mammalian cells. The use of nutrient feeding prevents the depletion of important medium components and results in improved culture longevity and high cell and product yields.
Costa, A. R., Rodrigues, E., Henriques, Mariana, Oliveira, Rosário, Azeredo, Joana   +4 more
openaire   +3 more sources

Fed-batch versus batch fermentation

Bioprocess Engineering, 1994
This article concerns the comparison between batch and fed-batch fermentation based on productivity and including the analysis of the implications on product manufacturing cost.
openaire   +1 more source

Feedback optimization of fed‐batch fermentation

Biotechnology and Bioengineering, 1987
AbstractThe problem of feedback optimization of the feed rate for fed‐batch fermentation processes is formulated in the framework of singular control theory and switching hypersurfaces. Using four differential balance equations that describe a general class of fedbatch processes and a general objective function to be minimized, it is shown that under ...
J M, Modak, H C, Lim
openaire   +2 more sources

Fed-Batch Cultures

2013
Many, if not most, industrially important fermentation and bioreactor operations are carried out in fed-batch mode, producing a wide variety of products. In spite of this, there is no single book that deals with fed-batch operations. This is the first book that presents all the necessary background material regarding the 'what, why and how' of optimal ...
Henry C. Lim, Hwa Sung Shin
openaire   +1 more source

Batch, fed-batch and repeated fed-batch fermentation processes of the marine thraustochytrid Schizochytrium sp. for producing docosahexaenoic acid

Bioprocess and Biosystems Engineering, 2013
Different fermentation processes, including batch, fed-batch and repeated fed-batch processes by Schizochytrium sp., were studied and compared for the effective DHA-rich microbial lipids production. The comparison between different fermentation processes showed that fed-batch process was a more efficient cultivation strategy than the batch process ...
Liang, Qu, Lu-Jing, Ren, Guan-Nan, Sun, Xiao-Jun, Ji, Zhi-Kui, Nie, He, Huang   +5 more
openaire   +2 more sources

Fermentation kinetics of recombinant yeast in batch and fed‐batch cultures

Biotechnology and Bioengineering, 1992
AbstractFed‐batch cultures of recombinant microorganisms have attracted attention as they can separate cell growth stage from cloned‐gene expression phase during fermentations. In this work, the effect of different glucose feeding strategies on cell growth and cloned gene expression was studied during aerobic fed‐batch fermentations of recombinant ...
A, Patkar, J H, Seo
openaire   +2 more sources

Growth of Photorhabdus luminescens in batch and glucose fed-batch culture

Applied Microbiology and Biotechnology, 2000
Photorhabdus luminescens, a bacterial symbiont of entomopathogenic biocontrol nematodes, was grown in batch and glucose fed-batch culture. The cell density, bioluminescence, production of antibiotic substances, number of cells with inclusion bodies, glucose concentration and oxygen uptake rate were recorded.
T, Jeffke, D, Jende, C, Mätje, R U, Ehlers, L, Berthe-Corti   +4 more
openaire   +2 more sources

The Snowball Effect in Fed-Batch Bioreactions

Biotechnology Progress, 2003
The bioreactor will play an important role in future biological manufacturing. For economic profit, important profiles of the feed rate in fed-batch cultures have been discussed. Unfortunately, the optimal feed rate is less robust. In these studies there exists the snowball effect in a substrate-inhibited bioprocess, in which substrate is accumulated ...
openaire   +2 more sources