ABSTRACT Despite the transformative impact of cancer immunotherapies such as immune checkpoint blockade, durable clinical responses remain limited. Increasing evidence indicates that antitumor immunity is governed not only by the tumor microenvironment, but also by systemic immune regulation mediated by peripheral immune organs. Among these, the spleen
Yuehua Liu, Xiaoqian Nie, Xiaofei Gao
wiley +1 more source
Effective semi-fed-batch saccharification with high lignocellulose loading using co-culture of Clostridium thermocellum and Thermobrachium celere strain A9. [PDF]
Nhim S +8 more
europepmc +1 more source
This work provides an effective strategy for selectively extracting 212Pb and 212Bi from the decay chain of 232Th as well as its mechanism illustration. Using the novel strategy, 2.07 MBq of 212Pb is successfully separated from 232Th and its daughters, which enables the supply of 212Pb/212Bi directly from the abundant natural thorium resource to be ...
Lifeng Chen +11 more
wiley +1 more source
Optimizing microbioreactor cultivation strategies for Trichoderma reesei: from batch to fed-batch operations. [PDF]
Rohr K +6 more
europepmc +1 more source
CellFreeGMF traces plasma cfRNA to likely originating cell types by integrating single‐cell atlases with graph‐regularized matrix factorization. The method decomposes cfRNA profiles into sample–cell contributions to reconstruct pseudo single‐cell expression.
Wenxiang Zhang +9 more
wiley +1 more source
Application of fed-batch strategy to fully eliminate the negative effect of lignocellulose-derived inhibitors in ABE fermentation. [PDF]
Branska B +3 more
europepmc +1 more source
SPARK decodes structure‐property relationships in anion exchange membranes (AEMs) via a chemically informed dual‐channel graph attention network (DEGAT) that explicitly captures microphase separation. It outputs five‐level grades for hydroxide conductivity and alkaline stability and highlights relevant key structural units, enabling robust pre ...
Wanting Chen +6 more
wiley +1 more source
Fed-Batch Strategy Achieves the Production of High Concentration Fermentable Sugar Solution and Cellulosic Ethanol from Pretreated Corn Stover and Corn Cob. [PDF]
Huang J, Li X, Zhao J, Qu Y.
europepmc +1 more source
Synaptic κ‐Ga2O3 Photodetectors for Privacy‐Enhancing Neuromorphic Computing
We report on a single‐element neuromorphic sensor based on the persistent photoconductivity (PPC) of κ‐phase Ga2O3 capable of sensing ultraviolet light and harnessing intrinsic data privacy. The approach establishes a materials‐enabled pathway toward compact, intelligent, and privacy‐enhancing optoelectronic hardware for next‐generation edge systems ...
Yanqing Jia +13 more
wiley +1 more source
Evaluation of disposable filtration systems for harvesting high cell density fed batch processes
Pegel Antje +4 more
doaj +1 more source

