Results 271 to 280 of about 304,733 (308)

Adaptive Optimal Control of Fed-Batch Alcoholic Fermentation

Applied Biochemistry and Biotechnology, 1998
An adaptive control scheme is developed for the optimization of a fed-batch ethanol production process. The fermentation process is modeled by an hybrid neural model combining mass balance equations and neural networks, used to represent the kinetic rates.
T L, Alves, A C, Costa, A W, Henriques, E L, Lima   +3 more
openaire   +2 more sources

The Snowball Effect in Fed-Batch Bioreactions

Biotechnology Progress, 2003
The bioreactor will play an important role in future biological manufacturing. For economic profit, important profiles of the feed rate in fed-batch cultures have been discussed. Unfortunately, the optimal feed rate is less robust. In these studies there exists the snowball effect in a substrate-inhibited bioprocess, in which substrate is accumulated ...
openaire   +2 more sources

Fed-batch operation of stirred reactors

Chemical Engineering Science, 1987
Abstract Numerical algorithm for the computation of the dependence of periodic solutions on parameters in fed-batch or periodically operating reactors is described. Results for the simulation of a simple model of anaerobic digester and of a first order exothermic reaction are then discussed and various types of m -periodic solutions are presented ...
Z. Kubičkova, M. Kubiček, M. Marek
openaire   +1 more source

Fed-batch and continuous culture

1990
Abstract A variety of techniques has been developed for the submerged culture of microorganisms. Batch and fed-batch culture have been part of the art of fermentation since antiquity and are still used today for most industrial fermentations.
openaire   +1 more source

Batch to Batch Iterative Learning Control of a Fed-Batch Fermentation Process

2012
Batch to batch iterative learning control of a fed-batch fermentation process is studied in this paper. Taking the immediate previous batch as the reference batch, a linearised model relating the deviations in the control profiles with the deviations in the quality variable trajectories is obtained.
Jie Zhang, Zhihua Xiong, Delautre Guillaume, Alexandre Lamande   +3 more
openaire   +1 more source

Optimal nonsingular control of fed‐batch fermentation

Biotechnology and Bioengineering, 1991
AbstractPresented is a new simple method for multidimensional optimization of fed‐batch fermentations based on the use of the orthogonal collocation technique. Considered is the problem of determination of optimal programs for fermentor temperature, substrate concentration in feed, feeding profile, and process duration.
openaire   +2 more sources

Reliable Batch-to-Batch Iterative Learning Control of a Fed-batch Fermentation Process

2012
Abstract A reliable batch-to-batch iterative learning control (ILC) strategy is proposed. A batch-wise linearised model of the batch process is obtained from historical process operation data and is used to derive the ILC strategy. In order to enhance the reliability of ILC, model prediction confidence is incorporated in the ILC optimisation ...
J. Jewaratnam, J. Zhang, A. Hussain, J. Morris   +3 more
openaire   +1 more source

Recent advances in fed-batch microscale bioreactor design

Biotechnology Advances, 2022
Sarah Teworte, Koray Malci, Murni Halim
exaly  

Fed‐batch microbioreactors

Biotechnology and Bioengineering, 2012
openaire   +1 more source

Optimization of batch and fed-batch bioreactors using simulated annealing.

Biotechnology progress, 2005
In order for biobased industrial products to compete economically with petroleum-derived products, significant reduction in their processing cost is necessary. Since most bioprocesses are operated in batch or fed-batch mode, their optimization involves theoretical and computational challenges.
openaire   +1 more source