Results 61 to 70 of about 440,405 (307)

Prop-Based Haptic Interaction with Co-location and Immersion: an Automotive Application [PDF]

open access: yes, 2005
Most research on 3D user interfaces aims at providing only a single sensory modality. One challenge is to integrate several sensory modalities into a seamless system while preserving each modality's immersion and performance factors.
Coquillart, Sabine, Ortega, Michael
core   +4 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Vibrotactile augmentation enhances late-phase control in sequential reaching without accuracy costs

open access: yesFrontiers in Human Neuroscience
IntroductionSequential goal-directed movements require the integration of advance planning and online control processes. However, the extent to which augmented sensory feedback influences these processes across multiple movement segments remains unclear.
Saba Mohammadalinezhad Kolahdouz   +4 more
doaj   +1 more source

Type II spiral ganglion afferent neurons drive medial olivocochlear reflex suppression of the cochlear amplifier. [PDF]

open access: yes, 2015
The dynamic adjustment of hearing sensitivity and frequency selectivity is mediated by the medial olivocochlear efferent reflex, which suppresses the gain of the 'cochlear amplifier' in each ear.
Cederholm, Jennie ME   +7 more
core   +2 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Tactile Gap Detection Deteriorates during Bimanual Symmetrical Movements under Mirror Visual Feedback. [PDF]

open access: yesPLoS ONE, 2016
It has been suggested that incongruence between signals for motor intention and sensory input can cause pain and other sensory abnormalities. This claim is supported by reports that moving in an environment of induced sensorimotor conflict leads to ...
Janet H Bultitude   +2 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Learning from sensory and reward prediction errors during motor adaptation. [PDF]

open access: yesPLoS Computational Biology, 2011
Voluntary motor commands produce two kinds of consequences. Initially, a sensory consequence is observed in terms of activity in our primary sensory organs (e.g., vision, proprioception).
Jun Izawa, Reza Shadmehr
doaj   +1 more source

Laminar fMRI: applications for cognitive neuroscience [PDF]

open access: yes, 2019
The cortex is a massively recurrent network, characterized by feedforward and feedback connections between brain areas as well as lateral connections within an area.
de Lange, Floris P.   +3 more
core   +2 more sources

Sensory Feedback and the Dynamic Control of Movement

open access: yesAnnual Review of Neuroscience
Motor systems in animals are highly dependent on sensory information for optimal control and precision, with mechanosensory feedback from the somatosensory system playing a critical role. These mechanosensory pathways are woven into the descending feedforward pathways and local central pattern generator circuits that control and generate movement ...
Martyn, Goulding   +2 more
openaire   +2 more sources

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