Results 71 to 80 of about 138,641 (267)

Robust Temporal Averaging of Time Intervals Between Action and Sensation

Frontiers in Psychology, 2019
Perception of the time interval between one’s own action (a finger tapping) and the associated sensory feedback (a visual flash or an auditory beep) is critical for precise and flexible control of action and behavioral decision.
Huanke Zeng, Lihan Chen
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

The Impact of Feedback on the Different Time Courses of Multisensory Temporal Recalibration

Neural Plasticity, 2017
The capacity to rapidly adjust perceptual representations confers a fundamental advantage when confronted with a constantly changing world. Unexplored is how feedback regarding sensory judgments (top-down factors) interacts with sensory statistics ...
Matthew A. De Niear, Jean-Paul Noel, Mark T. Wallace   +2 more
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

A Multimodal Stimulation System for Conveying Diverse Feedback in Hand Prosthetics: Preliminary Assessment

IEEE Transactions on Neural Systems and Rehabilitation Engineering
Artificial somatosensory feedback plays a crucial role in compensating for tactile and proprioceptive loss in prosthesis users. Although modern prosthetic systems can acquire rich sensory data, effectively conveying this multimodal information to the ...
Zhikai Wei, Aiguo Song, Fengkai Guo, Strahinja Dosen, Xuhui Hu, Ziyi Zhao, Xiyuan Zhao   +6 more
doaj   +1 more source

Effects of five-toed socks with multiple rubber bits on the foot sole on static postural control in healthy young adults

Journal of Physical Fitness and Sports Medicine, 2013
The purpose of this study was to assess the effectiveness of five-toed socks with multiple rubber bits on the foot sole in influencing static postural control among healthy young adults.
Junji Shinohara, Philip Gribble
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline

FEBS Open Bio, EarlyView.
Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey, Vaishnavi Sanjayan, Praveen Singh, Shantanu Sengupta, Anand Kumar Bachhawat   +4 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Multiplexed Piezoelectric Electronic Skin with Haptic Feedback for Upper Limb Prosthesis

Advanced Sensor Research
Upper limb amputation severely impairs tactile perception, limiting daily activities. Developing a near‐natural replacement with prosthetic devices requires improving user sensory experiences during object interactions.
Muhammad Awais, Easa AliAbbasi, Abdulkadir Yasin Atik, Mohammad Javad Bathaei, Mohsin Ali, Ritu Das, Cagdas Dag, Azmat Ullah, Rahul Singh, Kemal Sitki Turker, Cagatay Basdogan, Levent Beker   +11 more
doaj   +1 more source