Results 81 to 90 of about 440,405 (307)

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

The use of sensory feedback in the adaptation of perturbed /s/ [PDF]

open access: yes, 2008
The study investigates the contribution of tactile and auditory feedback in the adaptation of /s/ towards a palatal prosthesis. Five speakers were recorded via electromagnetic articulography, at first without the prosthesis, then with the prosthesis and ...
Brunner, Jana   +2 more
core   +2 more sources

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

open access: yesFEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa   +2 more
wiley   +1 more source

When Less Is More – Discrete Tactile Feedback Dominates Continuous Audio Biofeedback in the Integrated Percept While Controlling a Myoelectric Prosthetic Hand

open access: yesFrontiers in Neuroscience, 2019
State of the art myoelectric hand prostheses can restore some feedforward motor function to their users, but they cannot yet restore sensory feedback. It has been shown, using psychophysical tests, that multi-modal sensory feedback is readily used in the
Leonard F. Engels   +4 more
doaj   +1 more source

The persistence of a visual dominance effect in a telemanipulator task: A comparison between visual and electrotactile feedback [PDF]

open access: yes, 1981
The possibility to use an electrotactile stimulation in teleoperation and to observe the interpretation of such information as a feedback to the operator was investigated. It is proposed that visual feedback is more informative than an electrotactile one;
Gaillard, J. P.
core   +1 more source

Nonlinear modeling of FES-supported standing-up in paraplegia for selection of feedback sensors [PDF]

open access: yes, 2005
This paper presents analysis of the standing-up manoeuvre in paraplegia considering the body supportive forces as a potential feedback source in functional electrical stimulation (FES)-assisted standing-up.
Bajd, T.   +3 more
core   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

A comparison of visual and haltere-mediated equilibrium reflexes in the fruit fly Drosophila melanogaster [PDF]

open access: yes, 2003
Flies exhibit extraordinary maneuverability, relying on feedback from multiple sensory organs to control flight. Both the compound eyes and the mechanosensory halteres encode angular motion as the fly rotates about the three body axes during flight ...
Dickinson, Michael H., Sherman, Alana
core  

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Haptic Feedback Systems for Lower-Limb Prosthetic Applications: A Review of System Design, User Experience, and Clinical Insights

open access: yesBioengineering
Systems presenting haptic information have emerged as an important technological advance in assisting individuals with sensory impairments or amputations, where the aim is to enhance sensory perception or provide sensory substitution through tactile ...
Mohammadmahdi Karimi   +8 more
doaj   +1 more source

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