Results 81 to 90 of about 150,745 (309)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

The Effect of Vibrotactile Feedback on Healthy People and People with Vestibular Disorders during Dual-task Conditions [PDF]

open access: yes, 2013
Vibrotactile feedback (VTF) has been shown to improve balance performance in healthy people and people with vestibular disorders in a single-task experimental condition. However, typical balance activities occur in a multi-task environment.
Lin, Chia-Cheng
core  

A worldwide research overview of Artificial Proprioception in prosthetics.

open access: yesPLOS Digital Health
Proprioception is the body's ability to sense its position and movement, which is essential for motor control. Its loss after amputation poses significant challenges for prosthesis users.
Octavio Diaz-Hernandez
doaj   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Quantifying Physiological Response to Inadequate Sensory Feedback

open access: yes, 2018
Electrodermal activity (EDA) and electrocardiograms (ECG) have been shown to be strong indicators of physiological stress responses [1]. However, we do not know if EDA and ECG can also be used to quantify physiological response to inadequate sensory ...
Hemmerling, Robert   +7 more
core  

A Sensory Feedback Neural Stimulator Prototype for Both Implantable and Wearable Applications

open access: yesMicromachines
The restoration of sensory feedback is one of the current challenges in the field of prosthetics. This work, following the analysis of the various types of sensory feedback, aims to present a prototype device that could be used both for implantable ...
Federico Mereu   +6 more
doaj   +1 more source

Intelligent Tutoring Systems for Adult Learning in STEM Disciplines

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Intelligent tutoring systems (ITS) are reshaping adult learning in STEM by providing adaptive, data‐driven instruction across classrooms, workplaces, and informal environments. In the context of ITS, this article compares generative AI, which creates personalized explanations and practice materials, with explainable AI, which focuses on ...
Jill Zarestky, Amanda R. Lager Gleason
wiley   +1 more source

On the Coding of Negative Quantities in Cortical Circuits

open access: yes, 2008
Mullers Law of specific nerve energies introduced the idea that nerves transmit information about specific sensory features. This concept has been refined by the notion of 'labeled lines,' specific cells that capture sub-features of a sensory ...
Janneke Jehee   +2 more
core  

Cutaneous Force Feedback as a Sensory Subtraction Technique in Haptics

open access: yes, 2012
A novel sensory substitution technique is presented. Kinesthetic and cutaneous force feedback are substituted by cutaneous feedback (CF) only, provided by two wearable devices able to apply forces to the index finger and the thumb, while holding a handle
Claudio Pacchierotti   +4 more
core   +1 more source

A Multimodal Stimulation System for Conveying Diverse Feedback in Hand Prosthetics: Preliminary Assessment

open access: yesIEEE Transactions on Neural Systems and Rehabilitation Engineering
Artificial somatosensory feedback plays a crucial role in compensating for tactile and proprioceptive loss in prosthesis users. Although modern prosthetic systems can acquire rich sensory data, effectively conveying this multimodal information to the ...
Zhikai Wei   +6 more
doaj   +1 more source

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