Results 41 to 50 of about 82,643 (267)

Eigenstructure Assignment by State-derivative and Partial Output-derivative Feedback for Linear Time-invariant Control Systems

Acta Polytechnica, 2004
This paper introduces a parametric approach for solving the problem of eigenstructure assignment via state-derivative feedback for linear control time-invariant systems. This problem is always solvable for any controllable systems if the open-loop system
T. H. S. Abdelaziz, M. Valášek
doaj  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

FEEDBACK STABILIZATION OF HOMOGENEOUS POLYNOMIAL SYSTEMS [PDF]

IFAC Proceedings Volumes, 1995
The propose of this paper is to drive a simple necessary and sufficient stabilizability condition for a class of multi-inputs polnomial systems. This result represents a generalization of the main theorems of (Iggidr and Vivalda, 1992). The stabilizing feedbacks are explicitly given.
Iggidr, Abderrahman, Outbib, Rachid
openaire   +2 more sources

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

A Direct Algorithm for Pole Placement by State-derivative Feedback for Single-input Linear Systems

Acta Polytechnica, 2003
This paper deals with the direct solution of the pole placement problem for single-input linear systems using state-derivative feedback. This pole placement problem is always solvable for any controllable systems if all eigenvalues of the original system
Taha H. S. Abdelaziz, M. Valášek
doaj  

Boundary feedback stabilization of conformablelinear systems

Mathematical Modelling and Analysis
In this paper, we study the stabilization of infinitedimensional boundary control systems governed by the conformable derivative of order α ∈ (0, 1].
Abdellah Lourini, Mohamed El Azzouzi, Mohamed Laabissi   +2 more
doaj   +1 more source

Reverse quantum state engineering using electronic feedback loops

New Journal of Physics, 2012
We propose an all-electronic technique to manipulate and control interacting quantum systems by unitary single-jump feedback conditioned on the outcome of a capacitively coupled electrometer and, in particular, a single-electron transistor.
Gerold Kießlich, Clive Emary, Gernot Schaller, Tobias Brandes   +3 more
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Stabilizing Feedback Controls for Quantum Systems [PDF]

SIAM Journal on Control and Optimization, 2007
No quantum measurement can give full information on the state of a quantum system; hence any quantum feedback control problem is neccessarily one with partial observations, and can generally be converted into a completely observed control problem for an appropriate quantum filter as in classical stochastic control theory.
Mazyar Mirrahimi, Ramon van Handel
openaire   +3 more sources

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source