Results 51 to 60 of about 82,643 (267)

Feedback Stability of Negative Imaginary Systems [PDF]

IEEE Transactions on Automatic Control, 2017
This paper extends the robust feedback stability theorem of negative imaginary systems by removing restrictive assumptions on the instantaneous gains of the systems that were imposed in the earlier literature, and it further generalises this robust analysis result into the case that allows negative imaginary systems to have poles at the origin.
Alexander Lanzon, Hsueh-Ju Chen
openaire   +3 more sources

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

On the Feedback Stabilization of Boussinesq Equations

Annals of the Alexandru Ioan Cuza University - Mathematics, 2011
On the Feedback Stabilization of Boussinesq EquationsThis paper provides feedback stabilization results, preserving the invariance of a given convex set, for the Boussinesq system, in 2D and 3D. The proofs use an existence theorem for weak solutions.
openaire   +1 more source

Boundary feedback stabilization of Fisher’s equation [PDF]

Systems & Control Letters, 2016
The aim of this work is to design an explicit finite dimensional boundary feedback controller for locally exponentially stabilizing the equilibrium solutions to Fisher's equation in both $L^2(0,1)$ and $H^1(0,1)$. The feedback controller is expressed in terms of the eigenfunctions corresponding to unstable eigenvalues of the linearized equation.
Hanbing Liu, Peng Hu, Ionut Munteanu
openaire   +2 more sources

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

A correction note on "Output feedback stabilization"

IEEE Transactions on Automatic Control, 1994
In a previous paper by the authors (see ibid., vol. 35, no.8, p.951-4, 1990), necessary and sufficient Lyapunov-like conditions for output feedback stabilisation of nonlinear systems were derived. In this paper the authors point out an omission. >
Tsinias, J., Kalouptsidis, N.
openaire   +4 more sources

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Hybrid Feedback Stabilization of Fuzzy Nonlinear Systems

Journal of Control Science and Engineering, 2011
This paper is concerned with the problem of stabilizing one family of fuzzy nonlinear systems by means of fuzzy quantized feedback. The hybrid control strategy originating in earlier work by Brockett and Liberzon(2000) and Liberzon (2003) relies on the ...
Yingqi Zhang, Caixia Liu, Xiaowu Mu
doaj   +1 more source