Results 101 to 110 of about 2,258,876 (361)
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Conflict Resolution. Risk-As-Feelings Hypothesis [PDF]
Mathematical model of a goal-oriented thinking with feedback is described. Basic notions: decision graph, feed-back hierarchy and self-duality are introduced and explained. A source of the conflict in our approach is the ignorance about the importance of
Lavoslav Caklovic
core
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Effects of Nostalgia on Responses to Negative Feedback [PDF]
, 2018 Nostalgia is a bittersweet emotion evoked by memories of cherished personal experiences. Though nostalgia is a self-focused emotion, it has many interpersonal effects as well.
Avino, Michaela K +4 more
core +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Pregnant Women after Physical and Sexual Abuse in Germany [PDF]
, 2009 Background/Aims: The aim of our study was to evaluate the prevalence of abuse among pregnant women in Germany attending our antenatal outpatient clinic and to observe whether a history of abuse had consequences for women's feelings about their pregnancy.
Friese, Klaus +5 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
From Invisible to Visible: Exploring Invisibility Syndrome and Coping Among African American Men [PDF]
, 2018 INTRODUCTION: African American men may experience feelings of invisibility when maneuvering throughout the public education system. Encounters with alienation, discrimination, and prejudice play a major role in influencing one’s decision to remain in ...
Jones, Jesha, Lawson, Stacey
core +1 more source
19: Interdisciplinary Studies in the Long Nineteenth Century, 2007 ‘Feeling Dickensian feeling' asks why modern literary criticism, notably that inflected by new historicism, is so intent on stripping sentimentalism of its sentimental feeling. The essay suggests that the reader encounters experiential problems when feelings are separated from critical practice and also outlines the specific issues at stake when ...
openaire +2 more sources