Results 101 to 110 of about 778,919 (303)
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
To Feel or Not to Feel?—That Is the Question*
Pediatric Critical Care Medicine, 2020 openaire +4 more sources
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
An Archive of Feelings Trauma, Sexuality, and Lesbian Public Cultures
Examines trauma in many forms of lesbian popular culture in cultural, political, and depathologized ways.Intro -- Contents -- Acknowledgments -- Introduction -- 1 The Everyday Life of Queer Trauma -- 2 Trauma and Touch: Butch-Femme Sexualities -- 3 ...
Cvetkovich, Ann.
core
, 2015 Sarah Conn explores the complex feelings that accompany being an international student in the ...
Conn, S.
core +2 more sources
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
Ciencia y EnfermeríaOs objetivos desteõestudo foram identificar se as auxiliares e técnicas de enfermagem de urna unidade de internação médico-cirúrgica vivenciam sentímentos de satisfação e insatisfação no trabalho e identificar os fatores que mais contribuíram para a ...
JULIA TREVISAN MARTINS +2 more
doaj +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
“Love Your Enemy”: The Relativity of Absolute Love in D. H. Lawrence’s “The Ladybird”
Études Lawrenciennes, 2020 Marina Ragachewskaya
doaj +1 more source
Становление научных представлений об интеллектуальных чувствах в философско-психологическом дискурсе
Education & Pedagogy JournalВ статье освещаются основные исторические вехи становления философско-психологического дискурса об интеллектуальных чувствах и о роли эмоций в регуляции познавательной активности человека.
Кондратьева Арина Евгеньевна +1 more
doaj +1 more source