Results 81 to 90 of about 778,919 (303)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Mental health-related feelings.

open access: yes, 2022
Mental health-related feelings.
Markus Breuer (13550280)   +3 more
core   +1 more source

The Risk-as-feelings hypothesis in a Theory-of-planned-behaviour perspective

open access: yesJudgment and Decision Making, 2009
The Theory of Planned Behaviour (TpB: Ajzen, 1985; 1991) is based on a utility framework, and the Risk-as-Feelings hypothesis (RaF: Loewenstein, Weber, Hsee, & Welch, 2001) is a feelings-based behavioural model.
Therese Kobbeltved, Katharina Wolff
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Feeling Dickensian Feeling

open access: yes19: Interdisciplinary Studies in the Long Nineteenth Century, 2007
‘Feeling Dickensian feeling' asks why modern literary criticism, notably that inflected by new historicism, is so intent on stripping sentimentalism of its sentimental feeling. The essay suggests that the reader encounters experiential problems when feelings are separated from critical practice and also outlines the specific issues at stake when ...
openaire   +2 more sources

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

Participants’ feelings about schizophrenia.

open access: yes, 2022
Participants’ feelings about schizophrenia.
Akihiro Nishio (796981)   +1 more
core   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Hereditiy, Instinct and the Feelings

open access: yes, 1898
HEREDITIY, INSTINCT AND THE FEELINGS Hereditiy, Instinct and the Feelings (-
Hall, Granville Stanley
core   +2 more sources

Feelings Related to the Academic Path in Virtue of the COVID-19 Pandemic: Testimonies from Portuguese Higher Education Students Attending Healthcare Courses

open access: yesEuropean Journal of Mental Health, 2022
Introduction: In Portugal, two periods of confinement were implemented due to the COVID-19 pandemic (i.e., March 2020, January 2021), and closing the educational institutions was one of the containment measures adopted.
Beatriz MINGHELLI   +2 more
doaj  

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