The nucleoside analog GS-441524 strongly inhibits feline infectious peritonitis (FIP) virus in tissue culture and experimental cat infection studies [PDF]
N C Pedersen, B G Murphy
exaly +2 more sources
First study on in vitro antiviral and virucidal effects of flavonoids against feline infectious peritonitis virus at the early stage of infection [PDF]
Background and Aim: Feline infectious peritonitis (FIP), one of the most important infectious diseases in cats is caused by FIP virus (FIPV), a mutated variant of feline coronavirus.
Chanittha Triratapiban +5 more
doaj +1 more source
Successful in vitro propagation of feline coronavirus from clinically diagnosed feline infectious peritonitis cases using Vero cells: A potential model for future research. [PDF]
Abstract Background Feline coronavirus (FCoV) causes inapparent to progressive fatal feline infectious peritonitis (FIP) in domestic and wild cats, which affects multiple‐organ systems. Methods We investigated three clinically sick cats using different laboratory and molecular tests to diagnose and confirm FCoV and propagate the virus in Vero cell ...
Rana EA +5 more
europepmc +2 more sources
Characterization of peritoneal cells from cats with experimentally-induced feline infectious peritonitis (FIP) using RNA-seq. [PDF]
Laboratory cats were infected with a serotype I cat-passaged field strain of FIP virus (FIPV) and peritoneal cells harvested 2-3 weeks later at onset of lymphopenia, fever and serositis. Comparison peritoneal cells were collected from four healthy laboratory cats by peritoneal lavage and macrophages predominated in both populations.
Watanabe R +3 more
europepmc +8 more sources
Alpha-1-acid glycoprotein (AGP) is an acute-phase protein important in the immune response. It has been shown that AGP levels increase in cats with FIP, but also that some cats resistant to FIP may have transient increases in AGP.
G. Sironi +4 more
core +2 more sources
Feline infectious peritonitis (FIP) is a life-threatening infectious disease of cats caused by virulent feline coronavirus (FIP virus: FIPV). For the treatment of FIP, several effective antivirals were recently reported, but many of these are not ...
Tomomi Takano +2 more
doaj +1 more source
Feline Infectious Peritonitis (FIP) Virus
Summary The highest susceptibility for infection with FIP virus (6th passage level) by the intracerebral route was observed in mice between 1 and 4 days of age, as judged from the intensity and extent of immunofluorescence in sections through the brains, spinal cord and retina; other organs were consistently negative.
Horzinek, M.C. +3 more
openaire +6 more sources
Update on Feline Infectious Peritonitis [PDF]
Feline coronavirus (FCoV) infection in cats is common, usually only causing mild intestinal signs, such as diarrhoea. It is highly infectious and found worldwide.
Séverine Tasker +3 more
core +1 more source
Treatment With Remdesivir Alone or in Combination With GS-441524 in Cats With Ocular Involvement of Feline Infectious Peritonitis: An Observational Case Series. [PDF]
ABSTRACT Background Remdesivir and GS‐441524 have successfully treated cats with feline infectious peritonitis (FIP) but the changes in associated signs of ocular disease are not reported. Objective Evaluate the response of FIP‐associated signs of ocular disease before and after treatment with remdesivir, GS‐441524, or both.
Andrews ALMM +6 more
europepmc +2 more sources
One of the most common infectious causes of cat mortality is feline infective peritonitis (FIP), along with panleukopenia and viral upper respiratory tract infections. FIP is more likely to affect cats whose immune system is weak or suppressed.
Novakov Todor +6 more
doaj +1 more source

