Results 71 to 80 of about 2,010 (165)

Decreased sialylation of the acute phase protein α1-acid glycoprotein in feline infectious peritonitis (FIP)

Veterinary Immunology and Immunopathology, 2004
Feline infectious peritonitis (FIP) is an immune-mediated disease of domestic and exotic felides infected with feline coronavirus. FIP is characterized by the overexpression of an acute phase protein, the alpha1-acid glycoprotein (AGP). In humans, AGP is a heavily glycosylated protein that undergoes several modifications of its glycan moiety during ...
F. Ceciliani, C. Grossi, A. Giordano, V. Pocacqua, S. Paltrinieri   +4 more
openaire   +3 more sources

Serum Sialic Acid as a Biomarker of Inflammation and Infection: Insights From Veterinary Medicine

Veterinary Medicine International, Volume 2026, Issue 1, 2026.
Serum sialic acid (SSA) levels, including total sialic acid (TSA), lipid‐bound sialic acid (LBSA), and protein‐bound sialic acid (PBSA), have been extensively studied as biomarkers of inflammation and infection across various species and diseases. In parasitemic sheep, elevated SSA levels likely reflect host–pathogen interactions and immune activation.
Tina Yaghoobpour, Milad Faraji, Saeed Nazifi, Antonio Ortega-Pacheco   +3 more
wiley   +1 more source

Artificial Intelligence in Veterinary Clinical Pathology—An Introduction and Review

Veterinary Clinical Pathology, Volume 54, Issue S2, Page S13-S29, December 2025.
ABSTRACT Artificial intelligence (AI), particularly through machine learning and deep learning, presents opportunities for the enhancement of the workflow of the veterinary clinical pathologist. This review introduces basic concepts in AI in a nontechnical manner and explores the qualification and integration of AI in veterinary clinical pathology. The
Samuel V. Neal, Daniel G. Rudmann, Kara N. Corps   +2 more
wiley   +1 more source

Exploring Nirmatrelvir Derivatives Through P2 Substituent Modifications and Warhead Innovations Targeting the Main Protease of SARS‐CoV‐2

Archiv der Pharmazie, Volume 358, Issue 11, November 2025.
This study explores structural tuning of SARS‐CoV‐2 Mpro inhibitors through P2 position substitutions and novel warheads. Combining computational modeling and biochemical assays, we found that hydrophobic π‐rich groups and uncommon warheads like fluoro‐vinylsulfone or nitrile enhance potency.
Felipe Cardoso Prado Martins, Johannes Lang, Fernanda dos Reis Rocho, Xianxian Wang, Vinícius Bonatto, Jerônimo Lameira, Christian Klein, Carlos Alberto Montanari   +7 more
wiley   +1 more source

Successful management of feline pemphigus foliaceus with pentoxifylline and topical hydrocortisone aceponate

Veterinary Medicine and Science, 2022
The treatment regimen for feline pemphigus foliaceus (PF), an autoimmune disease caused by auto‐antibodies against proteins of the desmosome junction, usually includes high doses of oral or parenteral immunosuppressive drugs, typically glucocorticoids ...
Stefan Hobi, Julia A. Beatty, Jeanine R. Sandy, Vanessa R. Barrs   +3 more
doaj   +1 more source

Cellular composition and interferon-γ expression of the local inflammatory response in feline infectious peritonitis (FIP)

Veterinary Microbiology, 2005
Feline infectious peritonitis (FIP) is one of the most important viral diseases of cats. International studies estimate that approximately 80% of all purebred cats are infected with the causative agent, feline coronavirus (FCoV). Out of these, 5-12% develop clinical symptoms of FIP. The pathogenesis of the disease is complex with many unresolved issues
Berg, A.-L., Ekman, K., Belák, S., Berg, M.   +3 more
openaire   +2 more sources

From Challenge to Cure: A Look at Feline Infectious Peritonitis and Emerging Treatment Strategies and Breakthroughs

Veterinary Sciences
Background: Feline infectious peritonitis (FIP) is a complex and devastating viral disease in cats caused by feline coronavirus (FCoV). While FCoV is commonly encountered and typically innocuous, the emergence of a mutated variant can lead to the ...
Sheema Mir, Mykah Peters, Gloria Penny, Alexis Agsaoa, Mohammad Mir   +4 more
doaj   +1 more source

Diagnostic Methods for Feline Coronavirus: A Review

Veterinary Medicine International, 2010
Feline coronaviruses (FCoVs) are found throughout the world. Infection with FCoV can result in a diverse range of signs from clinically inapparent infections to a highly fatal disease called feline infectious peritonitis (FIP).
Saeed Sharif, Siti Suri Arshad, Mohd Hair-Bejo, Abdul Rahman Omar, Nazariah Allaudin Zeenathul, Amer Alazawy   +5 more
doaj   +1 more source

Practical Application of Disease Risk Assessment in Native Species Reintroductions: A Case Study of a European Wildcat (Felis silvestris) Population Reinforcement in the Cairngorms National Park

Mammal Review, Volume 55, Issue 4, October 2025.
Disease risk assessment was conducted for the Saving Wildcats reintroduction project of captive‐bred European Wildcats (Felis silvestris) to the Cairngorms National Park. Hazards were identified, and appropriate pre‐and post‐release mitigation strategies were identified and implemented, illustrating the direct conservation application and significance ...
Alice Bacon, Beatriz S. G. Alves, Simon Girling, Adam Naylor   +3 more
wiley   +1 more source

Expression of Feline Infectious Peritonitis (FIP) Coronavirus Antigens on the Surface of Feline Macrophage-Like Cells

Journal of General Virology, 1983
Growth of feline infectious peritonitis virus in a continuous feline cell line is described and evidence for the macrophage-like character of these cells is presented. Under one-step growth conditions, cytopathic changes and giant cell formation were observed 12 h after infection; more than 99% of the virus remained cell-associated 15 h after infection.
Horzinek, M.C., Jacobse-Geels, H.E.L.
openaire   +3 more sources