Feline Infectious Peritonitis Virus [PDF]
SummaryFrom ascitic fluids and liver homogenates of natural and experimentally induced cases of feline infectious peritonitis (FIP) virus particles have been purified by ammonium sulphate precipitation and sucrose gradient centrifugation; they appear as coronavirus‐like on the basis of their morphology (round, non‐rigid, about 100 nm.
Horzinek, M.C. +2 more
openaire +3 more sources
Successful in vitro propagation of feline coronavirus from clinically diagnosed feline infectious peritonitis cases using Vero cells: A potential model for future research. [PDF]
Abstract Background Feline coronavirus (FCoV) causes inapparent to progressive fatal feline infectious peritonitis (FIP) in domestic and wild cats, which affects multiple‐organ systems. Methods We investigated three clinically sick cats using different laboratory and molecular tests to diagnose and confirm FCoV and propagate the virus in Vero cell ...
Rana EA +5 more
europepmc +2 more sources
Feline Infectious Peritonitis Virus [PDF]
SummaryFeline infectious peritonitis (FIP) virus multiplication was demonstrated in the brains of one‐day‐old laboratory mice using direct immunofluorescence tests. Specificity was assessed by virus reisolation, indirect immunofluorescence and reproduction of FIP after inoculation of SPF kittens using brain material from the 6th mouse passage ...
Horzinek, M.C. +2 more
openaire +3 more sources
Feline infectious peritonitis: role of the feline coronavirus 3c gene in intestinal tropism and pathogenicity based upon isolates from resident and adopted shelter cats. [PDF]
Feline infectious peritonitis virus (FIPV) was presumed to arise from mutations in the 3c of a ubiquitous and largely nonpathogenic feline enteric coronavirus (FECV).
Golovko, Lyudmila +6 more
core +1 more source
Antigenic and biological diversity of feline coronaviruses: feline infectious peritonitis and feline enteritis virus [PDF]
Antigenically related feline coronaviruses cause two distinct disease manifestations in infected cats. The diseases are feline infectious peritonitis (FIP), in which the virus is widely disseminated, and feline enteric coronavirus (FECV), a mild disease in which the virus is usually limited to the villi.
Tupper, G. T. +3 more
openaire +2 more sources
Feline infectious peritonitis (FIP) is a disease of domestic cats caused by the genetic variant of the feline coronavirus (FCoV) and feline infectious peritonitis virus (FIPV), currently grouped into two serotypes, I and II.
Sarah Cook +4 more
doaj +1 more source
Colony Stimulating Factors in Early Feline Infectious Peritonitis Virus Infection of Monocytes and in End Stage Feline Infectious Peritonitis; A Combined In Vivo And In Vitro Approach. [PDF]
this was assessed alongside the in vivo situation in the hemolymphatic tissues of cats euthanized with natural end-stage FIP. For the in vitro work, isolated monocytes from SPF cats were cultured short-term and infected with the FIP virus (FIPV) strain DF2.
Malbon AJ +6 more
europepmc +2 more sources
Levels of feline infectious peritonitis virus in blood, effusions, and various tissues and the role of lymphopenia in disease outcome following experimental infection. [PDF]
Twenty specific pathogen free cats were experimentally infected with a virulent cat-passaged type I field strain of FIPV. Eighteen cats succumbed within 2-4 weeks to effusive abdominal FIP, one survived for 6 weeks, and one seroconverted without outward ...
Eckstrand, Chrissy +4 more
core +2 more sources
Enteritis due to Feline Infectious Peritonitis Virus
臨床・病理・血清学的にネコ伝染性腹膜炎(FIP)と診断され死亡したネコ4例および仔ネコの実験接種例14例について, 腸病変とウイルス抗原あるいはウイルス粒子の所在を検索した. 自然例2例および実験例12例が下痢を発した. 多くの病例の小腸・大腸粘膜は水腫性に肥厚し, 腸内容は水様~粘液状であった. 自然例3例および実験例12例の小腸・大腸病変は粘膜上皮の変性・剥離・増生を特徴とする比較的表在性の変化で, 固有層には浮腫, 少数の好中球お上び単核細胞浸潤がみられ, 隣接上皮細胞相互の癒合もしばしばみとめられた. しかし, 他の自然例1例および実験死亡例2例では, 小腸・大腸ともに炎症病変は激しく粘膜深部に及んでいた.
T, Hayashi +3 more
openaire +3 more sources
Emerging Viruses in the Felidae: Shifting Paradigms
The domestic cat is afflicted with multiple viruses that serve as powerful models for human disease including cancers, SARS and HIV/AIDS. Cat viruses that cause these diseases have been studied for decades revealing detailed insight concerning ...
Meredith A. Brown +6 more
doaj +1 more source

