Results 161 to 170 of about 487,569 (388)

Metabolic Stress‐Induced Choline Kinase α (CHKA) Activation in Endothelial Subpopulation Contributes to Diabetes‐Associated Microvascular Dysfunction

Advanced Science, EarlyView.
This study uncovers CHKA as a pivotal driver of vascular dysfunction in diabetic retinopathy and highlights its role in endothelial dysfunction through NAD⁺‐SIRT1‐Notch signaling. Single‐cell and functional analyses, combined with clinical and genetic validation, suggest CHKA as a promising therapeutic target for the prevention and treatment of ...
Ling Ren, Linyu Zhang, Yun Bai, Chang Huang, Xiaosa Li, Fanfei Ma, Wan Mu, Mudi Yao, Chang Jiang, Xiangjun Chen, Qin Jiang, Biao Yan   +11 more
wiley   +1 more source

Femur bone segmentation using a pressure analogy [PDF]

, 2014
Alathari, Thamer, Bah, Mamadou T., Nixon, Mark S.   +2 more
core   +1 more source

Three Cases of the Separation of the Epiphysis at the Head of the Femur [PDF]

, 1892
E. H. BRADFORD
openalex   +1 more source

Rictor Ameliorates Acute Antibody‐Mediated Rejection Following Kidney Transplantation by Suppressing Macrophage M1 Polarization Through p65‐NLRP3 Axis

Advanced Science, EarlyView.
This study elucidates the critical role of Rictor in macrophage activation in acute antibody‐mediated rejection (ABMR). Rictor increases K48‐linked ubiquitination of p65 by upregulating E3 ubiquitin ligase SOCS1, inhibiting transcriptional levels of NLRP3 and inflammasome activation.
Bin Ni, Chengcheng Yang, Junqi Zhang, Zhou Hang, Ming Zheng, Dengyuan Feng, Qinghuan Shen, Jinxu Miao, Xulin Sun, Li Sun, Baixin Shen, Min Gu, Zijie Wang   +12 more
wiley   +1 more source

Anterior approach for sciatic nerve localization: A novel observational pilot study utilizing sonoanatomical landmarks

The Indian Anaesthetists' Forum
Background: Anterior approach to sciatic nerve (SN) block has been an underutilized technique due to the technical difficulties and lack of accurate landmarks to guide the localization of the nerve.
Rupali Singh, Richa Jain, M. Rupinder Singh, Anju Grewal, Gaurav Singh   +4 more
doaj   +1 more source

Circular No. 2, War Department, S. G. O., Washington, January 2, 1869. A Report on Excisions of the Head of the Femur for Gunshot Injury [PDF]

J A
openalex   +1 more source

CASE OF RUPTURE OF QUADRICEPS FEMORIS TENDON WITH DISLOCATION OF PATELLA BENEATH THE INTERCONDYLOID GROOVE OF THE FEMUR [PDF]

, 1890
C. DEADERICK
openalex   +1 more source

Pyruvate Carboxylase in Macrophages Aggravates Atherosclerosis by Regulating Metabolism Reprogramming to Promote Inflammatory Responses Through the Hypoxia‐Inducible Factor‐1 Signaling Pathway

Advanced Science, EarlyView.
This study investigates the role of macrophage pyruvate carboxylase (PC) in atherosclerosis (AS) demonstrating that PC upregulation in macrophages promotes metabolism reprogramming to enhance inflammatory responses via the HIF‐1 signaling pathway.
Ling‐Na Zhao, Rui‐Ling Wang, Ran‐Xin Liu, Meng‐Ru Zheng, Li Zhao, Bao‐Feng Li, Jia‐Le Li, De‐Shen Liu, Xiao‐Xia He, Qin‐Bao Peng, Kai Li, Tian‐Xiao Lin, Ying‐Ying Liu, Sheng‐Ping He, Jun Lu, Shao‐Yi Zheng, Xiu Liu, Fang‐Ze Huang   +17 more
wiley   +1 more source

Finite element analysis of patient-specific additive-manufactured implants

Frontiers in Bioengineering and Biotechnology
Introduction: Bone tumors, characterized by diverse locations and shapes, often necessitate surgical excision followed by custom implant placement to facilitate targeted bone reconstruction.
Arman Namvar, Arman Namvar, Bill Lozanovski, David Downing, Tom Williamson, Tom Williamson, Endri Kastrati, Endri Kastrati, Darpan Shidid, David Hill, Ulrich Buehner, Stewart Ryan, Peter F. Choong, Reza Sanaei, Martin Leary, Milan Brandt   +15 more
doaj   +1 more source

PATHOLOGICAL FRACTURE OF THE NECK OF THE FEMUR, DUE TO THYROID METASTASIS

, 1923
I Zadek
openalex   +2 more sources