Results 41 to 50 of about 769 (206)

Early Stages Non-Traumatic Avascular Necrosis of Femoral Head Treated by Core Decompression With and Without Platelets Rich Plasma Injection: A Comparative Study

Acta Medica Iranica, 2021
Core decompression is one of the commonest used techniques in the handling of osteonecrosis of the pre-collapsed head of the femur. Core decompression had succeeded in preserving the hip joint and delaying the requisite for total hip replacement, but it ...
Ghadeer H. Majeed, Mohammed Sh Al-Edanni, Luay Jasim Abbood, Sadik AAl-Mukhtar   +3 more
doaj   +1 more source

Bioadhesive Hydrogel With Polyphenol‐Armored Nanogene Rejuvenates Chondrocyte Senescence for Aged Osteoarthritis Therapy

Advanced Science, EarlyView.
An adhesive hydrogel depot with polyphenol‐armored nanogenes is developed for treating aged osteoarthritis. This system maintains miR‐140 bioactivity, prolongs its intra‐articular retention, and enhances transfection into chondrocytes, leading to the downregulation of senescence‐associated pathways.
Liwei Yan, Runze Yang, Ting Zhou, Tianhao Xu, Yongqi Li, Yuelin Hu, Minghao Ge, Lei Zhang, Xiong Lu, Chaoming Xie, Weili Fu   +10 more
wiley   +1 more source

POST-TRAUMATIC AVASCULAR NECROSIS OF THE FEMORAL HEAD IN CHILDREN

, 1969
Two cases of post-traumatic avascular necrosis of the head of the femur without evident dislocation of the head or fracture of the head or neck are recorded.
Jörgen Stougêard
core   +1 more source

Morphometryic Analysis of Proximal Femoral Neck and Head of Dry Femur in Madhya Pradesh

, 2022
Background: Femur is widely studied in the fields of orthopedics, anthropology, forensic and human kinematics.  Mostly femoral fracture of upper end is involved. Most common cause of hip joint failure is osteoarthritis.
Kumar, V. (Vivek), Gajbhiye, V. M. (Vivekanand)   +1 more
core   +2 more sources

Targeting PLD3 Reverses the Immunosuppressive Niche by Reprogramming Tumor‐Associated Macrophages and Potentiates Antitumor Immunity

Advanced Science, EarlyView.
PLD3 activates the lysosomal‐AKT‐NF‐κB axis to drive cellular senescence in macrophages, establishing an immunosuppressive TME by limiting the infiltration of cytotoxic T, NK, and NKT cells, which confers resistance to anti‐PD‐1 therapy. Abrine inhibits PLD3 expression, restoring antitumor immunity and synergizing with anti‐PD‐1 treatment.
Xingtu Qin, Qiong Li, Xuemei Xu, Yuhan Wu, Yin Zhu, Jieqiong Wu, Yuan Fang, Qiubei Chen, Shuyang Wang, Jiang Yu, Yaping Ye, Hongli Jiao   +11 more
wiley   +1 more source

The diagnostic value of SPECT/CT in predicting the occurrence of osteonecrosis following femoral neck fracture: a prospective cohort study

BMC Musculoskeletal Disorders, 2020
Backgrounds One of the most significant complications after a femoral neck fracture is osteonecrosis of the femoral head (ONFH). The concomitant use of single-photon emission computed tomography (SPECT) with computed tomography (CT) increases the ...
Jae Youn Yoon, Soong Joon Lee, Kang Sup Yoon, Pil Whan Yoon   +3 more
doaj   +1 more source

Is Hyperbaric Oxygen Therapy Effective in Patients With Avascular Necrosis of the Femur Head?

Van Tıp Dergisi, 2021
INTRODUCTION: The aim of this study was to investigate the clinical and radiological results of exposure to high level of oxygen under high level of atmospheric pressure [Hyperbaric Oxygen (HBO) Therapy] in patients with Ficat Stage 1 and 2a avascular ...
Ibrahim Etli, Mehmet Ali Tokgöz, Ömer Faruk Kılıçaslan, Murat Yüncü, Vugar Nabi   +4 more
doaj   +1 more source

Oxygen Vacancy‐Enriched Platinum Single‐Atom Nanozyme Wrapped in Nanoislands: Unlocking Catalytic Activity and Reprogramming Redox Microenvironment for Osteonecrosis Repair

Advanced Science, EarlyView.
CeO2‐x/Pt single‐atom nano‐island is constructed via low‐temperature reduction, featuring abundant oxygen vacancies and an island–sea structure. It delivers outstanding multi‐enzyme‐mimetic activity and ROS‐scavenging efficiency. Density functional theory reveals optimized electronic structures and reaction pathways.
Yang Zhu, Zehui Lv, Xuejie Cai, Penghui Wei, Dengliang Wang, Zhao Wang, Ruoying Wang, Yingjie Wang, Xingdong Yang, Yixin Bian, Jiawei Xu, Xisheng Weng, Liangfeng Wei   +12 more
wiley   +1 more source

The effect of slip grade and chronicity on the development of femur avascular necrosis in surgically treated slipped capital femoral epiphyses

Acta Orthopaedica et Traumatologica Turcica, 2020
Objectives: We investigated the relationship between the grade and chronicity (acute-chronic) of the slip and the development of avascular necrosis (AVN) of the femoral head after surgery for slipped capital femoral epiphysis (SCFE).\nMethods: The study ...
Yakup Yildirim, Severino Bautista, Richard S. Davidson   +2 more
doaj  

Ayurvedic Management of Avascular Necrosis of head of Femur: A Case Report [PDF]

Journal of Clinical and Diagnostic Research
Avascular Necrosis (AVN) is a pathological condition characterised by a reduction in the blood supply to the subchondral bone, leading to the degenerative condition of the bone, marked by the death of cellular components of the bone.
Tanika Yadav, Vaishali Kuchewar, Pankaj Yadav   +2 more
doaj   +1 more source