Results 61 to 70 of about 53,591 (265)

Early Stages Non-Traumatic Avascular Necrosis of Femoral Head Treated by Core Decompression With and Without Platelets Rich Plasma Injection: A Comparative Study

Acta Medica Iranica, 2021
Core decompression is one of the commonest used techniques in the handling of osteonecrosis of the pre-collapsed head of the femur. Core decompression had succeeded in preserving the hip joint and delaying the requisite for total hip replacement, but it ...
Ghadeer H. Majeed, Mohammed Sh Al-Edanni, Luay Jasim Abbood, Sadik AAl-Mukhtar   +3 more
doaj   +1 more source

Oxygen Vacancy‐Enriched Platinum Single‐Atom Nanozyme Wrapped in Nanoislands: Unlocking Catalytic Activity and Reprogramming Redox Microenvironment for Osteonecrosis Repair

Advanced Science, EarlyView.
CeO2‐x/Pt single‐atom nano‐island is constructed via low‐temperature reduction, featuring abundant oxygen vacancies and an island–sea structure. It delivers outstanding multi‐enzyme‐mimetic activity and ROS‐scavenging efficiency. Density functional theory reveals optimized electronic structures and reaction pathways.
Yang Zhu, Zehui Lv, Xuejie Cai, Penghui Wei, Dengliang Wang, Zhao Wang, Ruoying Wang, Yingjie Wang, Xingdong Yang, Yixin Bian, Jiawei Xu, Xisheng Weng, Liangfeng Wei   +12 more
wiley   +1 more source

Engineered Exosomal miR‐146a‐5p Reprograms BMSC Fate and Restores Mitochondrial Homeostasis in Glucocorticoid‐Induced Osteonecrosis of Femoral Head

Advanced Science, EarlyView.
Exosomal miR‐146a‐5p is identified as a pivotal regulator in steroid‐induced osteonecrosis. Its reduction activates NF‐κB signaling, compromises mitophagy, and disrupts mitochondrial bioenergetics, resulting in autophagic disequilibrium. Engineered exosomes delivering miR‐146a‐5p reinstate mitochondrial function, augment oxidative phosphorylation and ...
Zehui Lv, Xuejie Cai, Yiming Xu, Xingdong Yang, Ruoying Wang, Han Wang, Yixin Bian, Jiawei Xu, Jiao Lu, Lulu Liu, Yingjie Wang, Jibin Song, Bin Feng, Xisheng Weng   +13 more
wiley   +1 more source

Femur, Head, with Necrosis [PDF]

, 2004
The Mütter Museum is one of the very few historical anatomical museums that still occasionally accepts donations of body parts if they are appropriate for the collection.

core  

Sartorius muscle pedicle iliac bone graft for the treatment of avascular necrosis of femur head

Journal of Hip Preservation Surgery, 2016
Avascular necrosis (AVN) of femoral head needs to be addressed early in the course of the disease, to prevent progression to osteoarthritis. A revascularizing procedure which can help preserve the head should be considered in young adults to alleviate ...
Raju Vaishya, A. Agarwal, Nishint Gupta, V. Vijay   +3 more
semanticscholar   +1 more source

A Dual‐Phase Exosomal Nanotherapy Enhances Continual Efferocytosis by Coordinating Checkpoint Inhibition and Metabolic Reprogramming in Atherosclerosis

Advanced Science, EarlyView.
Here we developed Am@SExo, a dual‐functional engineered exosome that coordinates CD47–SIRPα checkpoint blockade with Arg1 mRNA–mediated metabolic reprogramming. Surface SIRPα promotes recognition of apoptotic cells and plaque targeting, while Arg1 expression enhances arginine–ornithine metabolism, Rac1 activation, and actin remodeling in macrophages ...
Danwen Zheng, Shiteng Cai, Jinfeng Gao, Sheng Zhao, Bohan Wei, Xueyi Weng, Zhengmin Wang, Qiaozi Wang, Qiyu Li, Chengzhi Han, Weiyan Li, Yiwen Tan, Yuyuan Fu, Meng Ji, Zheyong Huang, Yanan Song, Juying Qian, Junbo Ge   +17 more
wiley   +1 more source

Ultrasound‐Activatable Piezoelectric Hydrogel Reprograms Mitochondrial Epigenetics for Osteoarthritis Therapy via the mTOR/GATD3A Axis

Advanced Science, EarlyView.
An ultrasound‐activatable piezoelectric hydrogel reprograms chondrocyte mitochondrial epigenetics via the mTOR/GATD3A axis, clearing damaged mitochondria and alleviating osteoarthritis progression in both mouse models and human cartilage explants. ABSTRACT The avascular nature of cartilage hinders drug delivery for osteoarthritis (OA) therapy.
Hui Zheng, Pengfei Yan, Peng Liu, Chang Yan, Mengqi Zhao, Zuyong Wang, Chao Ma, Rongkai Zhang, Xi Cui, Swee Hin Teoh   +9 more
wiley   +1 more source

The diagnostic value of SPECT/CT in predicting the occurrence of osteonecrosis following femoral neck fracture: a prospective cohort study

BMC Musculoskeletal Disorders, 2020
Backgrounds One of the most significant complications after a femoral neck fracture is osteonecrosis of the femoral head (ONFH). The concomitant use of single-photon emission computed tomography (SPECT) with computed tomography (CT) increases the ...
Jae Youn Yoon, Soong Joon Lee, Kang Sup Yoon, Pil Whan Yoon   +3 more
doaj   +1 more source

Is Hyperbaric Oxygen Therapy Effective in Patients With Avascular Necrosis of the Femur Head?

Van Tıp Dergisi, 2021
INTRODUCTION: The aim of this study was to investigate the clinical and radiological results of exposure to high level of oxygen under high level of atmospheric pressure [Hyperbaric Oxygen (HBO) Therapy] in patients with Ficat Stage 1 and 2a avascular ...
Ibrahim Etli, Mehmet Ali Tokgöz, Ömer Faruk Kılıçaslan, Murat Yüncü, Vugar Nabi   +4 more
doaj   +1 more source

Impact of COVID-19 infection in the occurrence of avascular necrosis of head of femur: a case series in a tertiary care hospital in Central Gujarat

International Journal of Community Medicine and Public Health
Avascular necrosis (AVN) is a degenerative bone condition characterized by the death of bone tissue due to reduced blood supply. Recent studies suggest an increased incidence of AVN in post-COVID-19.
Fatimakhatun Z. Memon, G. Dumra, Dhruvi Joshi, Vivek Mehta, Nisarg Shah   +4 more
semanticscholar   +1 more source