Results 71 to 80 of about 53,591 (265)

Ubiquitination of ACSL4 by Parkin Suppresses Ferroptosis and Rescues Glucocorticoid‐Induced Bone Loss

Advanced Science, EarlyView.
GCs reduce Parkin, leading to ACSL4 accumulation and PUFA‐phospholipid‐driven ferroptosis in BMSCs, which impairs osteogenesis and promotes adipogenesis, causing GIOP. Parkin restoration (via OE‐Parkin or Parkin‐LNP@DSS6) ubiquitinates and degrades ACSL4, inhibiting ferroptosis, rescuing bone formation, and rescues GIOP bone loss.
Li‐jiang Han, Jian‐sen Miao, Yi‐feng Shi, Yi‐ting Tu, Yu‐zhe Lin, Lin‐Jie Chen, Bing‐hao Lin, Hua‐lin Li, Xuan‐qi Zheng, Hong‐qiang Wu, Hai‐xiao Liu, Lei Yang, Ai‐min Wu, Zhen Lin, Jian Xiao, Gang Zheng, Chen Jin   +16 more
wiley   +1 more source

AVASCULER NECROSIS OF THE FEMUR HEAD IN A CASE USING STEROID AND WITH SALMONELLA ENTERITIDIS BACTEREMIA [PDF]

, 2012
Avascular necrosis of the femur head in adults has been associated with a variety of disease entities. It is usually recognized as a potential complication of trauma or systemic corticosteroid therapy and chronic alcoholism. We present an unusual case of
Acar, Ali, Cavuslu, Saban, Diktas, Husrev, Oncul, Oral   +3 more
core  

Avascular necrosis of lateral femoral condyle in a middle-aged woman from central India

Radiology Case Reports
Bone infarcts, also called avascular necrosis of the knee or osteonecrosis, are defined as the anoxic death of the bone parts caused by interrupted blood supply and can occur in any bone of the body. It is most associated with trauma, sickle cell disease,
Achal Gulghane, Msc, Kavita Gomase, PhD, Vaishali Taksande, PhD, Anshul Sood, MBBS, MD   +3 more
doaj   +1 more source

Spontaneous bone infarction of the distal femur in a patient with Cushing's disease: a case report

Bone Reports, 2021
Avascular necrosis of the femoral head is a well-known complication of treatment with high dosage glucocorticoids and has been described in a few patients with Cushing's syndrome.
Pepijn van Houten, Jacky de Rooy, Ingrid van der Geest, Romana Netea-Maier, Annenienke van de Ven   +4 more
doaj   +1 more source

Dual Labral and Ligamentum Teres Reconstruction Achieves High Functional Outcomes and Arthroplasty‐Free Survivorship at 2 Years

Arthroscopy, Sports Medicine, and Rehabilitation, EarlyView.
Purpose To evaluate the clinical outcomes and survivorship of hip arthroscopy with simultaneous labral and ligamentum teres (LT) reconstruction for the treatment of irreparable labral and LT tears, with a minimum follow‐up of 2 years. Methods Prospectively collected data were retrospectively reviewed for patients who underwent combined arthroscopic ...
Roger Quesada‐Jimenez, Krishi Rana, Matthew J. Strok, Ady H. Kahana‐Rojkind, Alexander K. Burt, Etan P. Sugarman, Benjamin G. Domb   +6 more
wiley   +1 more source

Femoral head avascular necrosis: etiopathogenesis, diagnostics and treatment – literature review / [PDF]

Background. Avascular necrosis of the femoral head is characterized by diminished blood flow to the femur's head, which leads to osteonecrosis, and results in the eventual structural collapse of the femoroacetabular joint.
Jokubynas, Vėjas Vytautas,
core   +1 more source

Open Multiligament Reconstruction for Concomitant Patellofemoral and Type IV Tibiofemoral Dislocation and Bucket‐Handle Medial Meniscus Injury

Arthroscopy Techniques, EarlyView.
Abstract A knee dislocation combined with a patellofemoral dislocation is an extremely rare and complex injury that reflects severe multidirectional instability and extensive soft‐tissue disruption. We show an open single‐stage anatomic reconstruction method for a patient with type IV tibiofemoral dislocation, patellofemoral dislocation, and bucket ...
Sina Javidmehr, Armin Akbarzadeh, Robert F. LaPrade   +2 more
wiley   +1 more source

Relationship of idiopathic femoral head necrosis with blood lipid metabolism and coagulation function: A propensity score-based analysis

Frontiers in Surgery, 2023
BackgroundNontraumatic osteonecrosis of the femoral head (ONFH) can be corticosteroid-induced, alcohol-induced, and idiopathic ONFH (IONFH). Although corticosteroid- and alcohol-induced ONFH has been investigated extensively regarding its relationship ...
Xiaolong Yu, Shengtao Zhang, Bin Zhang, Min Dai   +3 more
doaj   +1 more source

Prediction Value of SPECT/CT in Avascular Necrosis of Femoral Head After Femur Neck Fracture

Geriatric Orthopaedic Surgery & Rehabilitation, 2019
Introduction: The aim of this study was to determine the diagnostic value of single-photon emission computed tomography/computed tomography (SPECT/CT) in prediction of avascular necrosis (AVN) after femoral neck fracture and to evaluate whether photon ...
Sung Jun Park, B. Ko, K. Moon, Minkyung Lee   +3 more
semanticscholar   +1 more source

INITIAL RIGID FIXATION TECHNIQUES FOR ACETABULAR CUP IN CEMENTLESS TOTAL HIP ARTHROPLASTY

Pakistan Armed Forces Medical Journal, 2018
Objective: To see the effectiveness of press fit technique to achieve initial rigid stability for Acetabular cup in cementless total hip arthroplasty (THA) done for Osteonecrosis of femoral head (ONFH) in our setting. Study Design: Case series.
Asim Niaz Naqvi, Saman Waqar
doaj   +4 more sources