Results 21 to 30 of about 13,529 (168)

Comparison of efficacy and safety of choline fenofibrate (fenofibric acid) to micronized fenofibrate in patients of mixed dyslipidemia: A randomized, open-label, multicenter clinical trial in Indian population

Indian Journal of Endocrinology and Metabolism, 2016
Introduction: Choline fenofibrate is a newly developed choline salt of fenofibric acid, which is more hydrophilic than fenofibrate. This study was initiated to evaluate the safety and efficacy of choline fenofibrate in comparison to micronized ...
Piyush Patel, Hanmant Barkate
doaj   +1 more source

Fenofibrate and losartan [PDF]

Annals of the Rheumatic Diseases, 2003
Should we take advantage of their uricosuric properties in clinical practice? The interesting study published in this issue of the journal by Takahashi et al sheds light on two drugs, losartan and fenofibrate, which have hypouricaemic properties, in addition to their main therapeutic effects.1 Losartan potassium is an orally active angiotensin II ...
openaire   +2 more sources

Fenofibrate diminishes the self-renewal and metastasis potentials of oral carcinoma stem cells through NF-κB signaling

Journal of the Formosan Medical Association, 2022
Background/Purpose: NF-κB family of transcription factors are the major contributors to malignant tumor progression, maintenance of cancer stemness, and enhancement of chemoresistance.
Tzu-Rong Su, Cheng-Chia Yu, Shih-Chi Chao, Chun-Chung Huang, Yi-Wen Liao, Pei-Ling Hsieh, Chuan-Hang Yu, Shih-Shen Lin   +7 more
doaj   +1 more source

Fenofibrate Improves Insulin Resistance and Hepatic Steatosis and Regulates the Let-7/SERCA2b Axis in High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease Mice

Frontiers in Pharmacology, 2022
Fenofibrate is widely used in clinical therapy to effectively ameliorate the development of non-alcoholic fatty liver disease (NAFLD); however, its specific molecular mechanism of action remains largely unknown.
Dan Zhang, Shanzhuang Niu, Yicheng Ma, Hang Chen, Yu Wen, Mingke Li, Bo Zhou, Yi Deng, Chunjing Shi, Guangyu Pu, Meng Yang, Xianmei Wang, Chenggang Zou, Yuanli Chen, Lanqing Ma   +14 more
doaj   +1 more source

Fenofibrate increases HDL-cholesterol by reducing cholesteryl ester transfer protein expression

Journal of Lipid Research, 2007
In addition to efficiently decreasing VLDL-triglycerides (TGs), fenofibrate increases HDL-cholesterol levels in humans. We investigated whether the fenofibrate-induced increase in HDL-cholesterol is dependent on the expression of the cholesteryl ester ...
Caroline C. van der Hoogt, Willeke de Haan, Marit Westerterp, Menno Hoekstra, Geesje M. Dallinga-Thie, Johannes A. Romijn, Hans M.G. Princen, J. Wouter Jukema, Louis M. Havekes, Patrick C.N. Rensen   +9 more
doaj   +1 more source

Hypertriglyceridemic Acute Pancreatitis With Concomitant Retrocecal Appendicitis: A Case Report. [PDF]

Clin Case Rep
ABSTRACT Hypertriglyceridemia‐induced acute pancreatitis and acute appendicitis are distinct clinical conditions rarely reported to occur concurrently. We present a case of hypertriglyceridemia‐induced pancreatitis characterized by clinical deterioration despite a decline in serum triglyceride levels.
Esfahani MS, Shekarchizadeh M, Tabatabaei SAD, Tabatabaei MD.   +3 more
europepmc   +2 more sources

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

The effect of fenofibrate on early retinal nerve fiber layer loss in type 2 diabetic patients: a case-control study

BMC Ophthalmology, 2018
Background Previous studies suggested that use of fenofibrate could significantly reduce the rate of progression into diabetic retinopathy (DR), and that retinal nerve fiber layer (RNFL) loss, which has been considered an important indicator for retinal ...
Rui Shi, Lei Zhao, Yun Qi
doaj   +1 more source

Fenofibrate and Crataegus oxyacantha is an effectual combo for mixed dyslipidemia

Biomedical and Biotechnology Research Journal, 2020
Background: Dyslipidemia (DL) is a blood lipid disorder characterized by high cholesterol, triglyceride and low density lipoprotein with reduction of high density lipoprotein.
Huda A Rasheed, Nawar R Hussien, Marwa S Al-Naimi, Hayder M Al-Kuraishy, Ali I Al-Gareeb   +4 more
doaj   +1 more source

Pleiotropic Effects of Fenofibrate

Current Pharmaceutical Design, 2009
Fenofibrate represents the most commonly used fibric acid derivative. The drug exerts its metabolic effects by modulating the expression of several genes involved in lipoprotein metabolism. In addition, numerous studies suggest that fenofibrate may also affect the progression of the atherosclerotic process by several lipid-independent mechanisms.
Tsimihodimos, V., Liberopoulos, E., Elisaf, M. S.   +2 more
openaire   +3 more sources