Results 1 to 10 of about 172,502 (392)
Fentanyl: Receptor pharmacology, abuse potential, and implications for treatment. [PDF]
Neuroscience and Biobehavioral Reviews, 2019 Opioid overdoses, many of which are attributed to use of illicit fentanyl, are currently one of the leading causes of death in the U.S. Although fentanyl has been used safely for decades in clinical settings, the widespread use of illicit fentanyl is a ...
Cahill, Catherine M, Comer, Sandra D
core +3 more sources
Oral fentanyl consumption and withdrawal impairs fear extinction learning and enhances basolateral amygdala principal neuron excitatory-inhibitory balance in male and female mice [PDF]
Addiction NeuroscienceThe number of opioid overdose deaths has increased over the past several years, mainly driven by an increase in the availability of highly potent synthetic opioids, like fentanyl, in the un-regulated drug supply.
Anthony M. Downs +2 more
doaj +2 more sources
Correlates of fentanyl preference among people who use drugs in Rhode Island [PDF]
Harm Reduction JournalBackground Fentanyl is increasingly pervasive in the unregulated drug supply and is a driver of drug overdose deaths in the United States. The aims of this study were to characterize and identify correlates of fentanyl preference among people who use ...
Siena C. Napoleon +8 more
doaj +2 more sources
medRxiv, 2022 Aims: To characterize polysubstance death in the United States during the transition to the fourth wave of the overdose crisis. To characterize co-involved substances in fatal overdose involving synthetic opioids (mainly illicitly manufactured fentanyl ...
Joseph R. Friedman, Chelsea L. Shover
semanticscholar +1 more source
Injury Prevention, 2021 Reports from active drug users state that xylazine, the veterinary tranquilliser, has been increasing in the illicit drug supply in Philadelphia. To describe trends and characteristics of unintentional deaths from heroin and/or fentanyl overdose with ...
Jewell Johnson +3 more
semanticscholar +1 more source
Evidence of Buprenorphine-precipitated Withdrawal in Persons Who Use Fentanyl
Journal of addiction medicine, 2021 Objectives Buprenorphine can precipitate withdrawal in opioid-dependent persons with recent fentanyl use. However, the prevalence of this phenomenon is not clinically established.
Neil B. Varshneya +4 more
semanticscholar +1 more source
Patterns of Routes of Administration and Drug Tampering for Nonmedical Opioid Consumption: Data Mining and Content Analysis of Reddit Discussions [PDF]
J Med Internet Res 2021;23(1):e21212, 2021 The complex unfolding of the US opioid epidemic in the last 20 years has been the subject of a large body of medical and pharmacological research, and it has sparked a multidisciplinary discussion on how to implement interventions and policies to effectively control its impact on public health.
arxiv +1 more source
The anomalous pharmacology of fentanyl
British Journal of Pharmacology, 2021 Fentanyl is a key therapeutic, used in anaesthesia and pain management. It is also increasingly used illicitly and is responsible for a large and growing number of opioid overdose deaths, especially in North America.
E. Kelly +5 more
semanticscholar +1 more source
Mass Spectral Character of Fentanyl Analogues [PDF]
Fayixue Zazhi, 2019 Objective To provide the reference for the identification of unknown fentanyl analogues by studying the characteristic ions and main fragmentation pathways of fentanyl analogues in the modes of collision induced dissociation （CID） and electron ionization
YAN Jin, HUA Zhen-dong, JIA Wei, et al.
doaj +1 more source