Results 241 to 250 of about 184,026 (339)

Dexmedetomidine vs. Propofol-Fentanyl for Bispectral Index (BIS)-Guided Sedation During Awake Fiberoptic Intubation in Neurosurgical Patients With Anticipated Difficult Airways: An Observational Study. [PDF]

Cureus
Bathala MR, Sethuraman M, Madhusudan S, Turimella A, Syeda S, Lakshminarasimhaiah G, Musti S, Bhandge S.   +7 more
europepmc   +1 more source

Repeated Tetrahydrocannabinol Injections Induce Tolerance but Do Not Disrupt Ongoing Behaviour Upon Withdrawal in Male and Female Rats With Inflammatory Pain

European Journal of Pain, Volume 30, Issue 5, May 2026.
ABSTRACT Background Many people use cannabis to self‐medicate for pain. Little is known about the impact of pain on tolerance and spontaneous withdrawal to delta‐9‐tetrahydrocannabinal (THC), the primary psychoactive compound in cannabis. Our previous research with the opioid morphine suggests persistent pain will increase the magnitude and duration of
Michael M. Morgan, Christa M. Hickey
wiley   +1 more source

Antecedents of Fentanyl Coinvolvement in Deaths Attributed to Stimulant Poisoning in San Francisco, CA. [PDF]

J Addict Med
Chang YG, McMahan VM, Rodda LN, Antolin Muñiz M, Brennan S, Luna Marti X, Lutz SM, Knoll J, Coffin PO.   +8 more
europepmc   +1 more source

Effects of Virtual Reality on Anxiety, Stress, Pain, and Patient Satisfaction Among Palestinian Patients Undergoing Colonoscopy: Randomized Controlled Trial

Health Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background and Aims Colonoscopy frequently causes significant pre‐procedural anxiety and intra‐procedural pain. This randomized controlled trial evaluated immersive, culturally adapted virtual reality (VR) therapy on anxiety, perceived stress, pain, patient satisfaction, and hemodynamic stability in Palestinian adults undergoing colonoscopy ...
Khulud Mansor, Ibrahim Aqtam, Mustafa Shouli   +2 more
wiley   +1 more source

The Effect of Iclepertin on Hematological Parameters: An Overview of Nonclinical Studies and Clinical Trials in Healthy Volunteers and Patients with Cognitive Impairment Associated with Schizophrenia

The Journal of Clinical Pharmacology, Volume 66, Issue 5, May 2026.
Abstract There are currently no approved pharmacotherapies to treat cognitive impairment associated with schizophrenia (CIAS). Iclepertin (BI 425809) is a selective glycine transporter‐1 (GlyT1) inhibitor that was investigated for the treatment of CIAS.
Peter Nagy, Justin Corey Fowler, Holger Rosenbrock, Wenbo Tang, Eric Fu, Annie Fraser, Holly Dursema, Julia Schlichtiger, Michael Desch, Fredrik Gruenenfelder   +9 more
wiley   +1 more source

Membrane Permeability Drives the Extreme Potency of Fentanyl. [PDF]

JACS Au
Clayton J, Farmer GJ, Glenn J, Mistry SN, Lane JR, Shi L, Stavitskaya L, Canals M, Shen J.   +8 more
europepmc   +1 more source

Weaning Drug Manufacturers Off Their Painkiller: Creating an Exception to the Learned Intermediary Doctrine in Light of the Opioid Crisis [PDF]

, 2019
Max Roberts
core   +1 more source

Inpatient Opioid Use in Head and Neck Microvascular Free Flap Reconstruction

Otolaryngology–Head and Neck Surgery, Volume 174, Issue 5, Page 1230-1235, May 2026.
Abstract Objectives The primary objective is to determine whether patients undergoing osseous microvascular free flap reconstruction of head and neck defects have higher inpatient pain requirements than those undergoing nonosseous reconstruction. Secondary aims include evaluating the impact of a multimodal analgesia (MMA) protocol and COVID‐19 visitor ...
Patricia Timothee, Alessandra Bliss, Daniel Blumenthal, John Dowd, Emily Clementi, Bruce Davidson, Michael Reilly, Matthew Pierce, Jonathan Giurintano   +8 more
wiley   +1 more source

Brain oxygen responses induced by arousing stimuli and fentanyl: generalized or structure-specific? [PDF]

Am J Physiol Regul Integr Comp Physiol
Limiac FG, Arce A, Kiyatkin EA.
europepmc   +1 more source

Examining buprenorphine compared to methadone for likelihood of overdose during pregnancy, 2014–2021

Pregnancy, Volume 2, Issue 3, May 2026.
Abstract Objective To examine the likelihood of experiencing an overdose among women receiving any buprenorphine (with or without naloxone) compared to women receiving methadone during pregnancy. Methods Data from the MATernaL and Infant clinical NetworK (MAT‐LINK), a longitudinal surveillance system of pregnant woman–child dyads using electronic ...
Amy Board, Alana M. Vivolo‐Kantor, Shin Y. Kim, Shawn A. Thomas, Emmy L. Tran, Mishka Terplan, Pilar M. Sanjuan, Marcela C. Smid, Tanner Wright, Neil S. Seligman, Patrick D. Schneider, Autumn Davidson, Michelle L. Henninger, Elisha M. Wachman, Kara M. Rood, Luigi Garcia Saavedra, Judette Louis, Diane Morse, Julie Shakib, Kelley A. Saia, Kathryn Miele   +20 more
wiley   +1 more source