Results 221 to 230 of about 87,215 (304)

Modeling Supports Combinatorial Effects Between Pharmacological and Non‐Pharmacological Interventions to Prevent Opioid‐Induced Cardiac Arrest

Clinical Pharmacology &Therapeutics, Volume 119, Issue 6, Page 1466-1475, June 2026.
Few studies have quantified the effects of non‐pharmacological interventions (e.g., rescue breathing) in the setting of community opioid overdose. We extended a previously validated model for opioid antagonists by incorporating the mechanism of rescue breathing, and quantified combinatorial effects between rescue breathing and various formulations of ...
Bradlee Thrasher, John Mann, Anik Chaturbedi, Shilpa Chakravartula, Hamed Meshkin, Affan Affan, Alexander Galluppi, Ji Young Kim, Nigar Karimli, Yue Han, Zachary Dezman, Jeffry Florian, Zhihua Li   +12 more
wiley   +1 more source

G protein regulatory network shapes magnitude and kinetics of behavioral responses in an engineered opioid receptor model. [PDF]

J Biol Chem
Coleman DL, Ren RJ, Opperman KJ, Kwan EX, Martemyanov KA, Grill B.   +5 more
europepmc   +1 more source

Microelectrode array scaled for human hippocampal slices

Epilepsia Open, Volume 11, Issue 3, Page 777-786, June 2026.
Abstract Objective Temporal lobe epilepsy (TLE) is characterized by recurrent seizures originating usually from the hippocampus, and approximately one‐third of TLE patients remain refractory to pharmacological interventions. Surgical resection offers a potential cure for refractory TLE cases, with approximately 70% achieving seizure freedom. Still, the
Anssi Pelkonen, Vera Lezhneva, Tomi Ryynänen, Joose Kreutzer, Valeriia Sitnikova, Mireia Gómez‐Budia, Adriana Della Pietra, Antonios Dougalis, Jenni Kyyriäinen, Mastaneh Torkamani‐Azar, Henri Eronen, Tuomas Rauramaa, Arto Immonen, Ville Leinonen, Alejandra Sierra, Reetta Kälviäinen, Tarja Malm   +16 more
wiley   +1 more source

Xylazine exacerbates fentanyl-induced respiratory depression and prevents rescue by naloxone in mice. [PDF]

Psychopharmacology (Berl)
Watkins JM, Hahn R, Dempsey M, Hohmann AG.   +3 more
europepmc   +1 more source

Pain Trajectories and Predictors Following Uterine Artery Embolization Using a Nitroglycerin–Lidocaine Protocol: A Prospective Study

Health Science Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Background and Aims Uterine artery embolization (UAE) is an effective minimally invasive treatment for symptomatic fibroids; however, post‐procedural pain remains a major limitation. Intra‐arterial lidocaine administration has shown inconsistent results with concerns regarding vasospasm and incomplete embolization.
Fatemeh Mahdavi Sabet, Hamed Ghorani, Ali Mahdavi   +2 more
wiley   +1 more source

Microcirculatory impact of vatinoxan and fentanyl in male Wistar rats sedated with medetomidine and midazolam. [PDF]

BMC Vet Res
Lindh E, Meller A, Alm K, Raekallio M, Honkavaara J.   +4 more
europepmc   +1 more source

External cephalic version outcomes with tocolysis and sedation: A 10‐year retrospective cohort study

International Journal of Gynecology &Obstetrics, Volume 173, Issue 3, Page 1343-1351, June 2026.
Abstract Objective To evaluate the effectiveness and safety of external cephalic version (ECV) performed with tocolysis and sedation or spinal anesthesia, and to identify predictors of ECV success, complications, and delivery outcomes after successful ECV. Methods This 10‐year cohort study included 990 pregnant women with term non‐cephalic presentation
Javier Sánchez‐Romero, Rosa María Gallego‐Pozuelo, José Eliseo Blanco‐Carnero, Javier Herrera‐Giménez, Fernando Araico‐Rodríguez, Alberto Rafael Guijarro‐Campillo, Aníbal Nieto‐Díaz, Catalina de Paco‐Matallana   +7 more
wiley   +1 more source

Epistemic Barriers to Buprenorphine Access for Adolescents With Opioid Use Disorder. [PDF]

Cureus
Babul A, Ashraf S, Elmes R, Mahdavi P.
europepmc   +1 more source

Acute Pericardial Effusion After Vein of Marshall Ethanol Infusion for Persistent Atrial Fibrillation

Journal of Arrhythmia, Volume 42, Issue 3, June 2026.
This study reports a 25.2% incidence of acute pericardial effusion following vein of Marshall ethanol infusion for persistent atrial fibrillation. The extent of the resulting low‐voltage area was identified as an independent predictor of pericardial effusion, reflecting the magnitude of chemical injury.
Hualong Li, Jianlong Yin, Jian Liang, Ning Huang, Teng Li   +4 more
wiley   +1 more source

Efficacy of a Novel Ablation Index Algorithm for Cavotricuspid Isthmus Ablation Using a Flexible‐Tip Ablation Catheter

Journal of Arrhythmia, Volume 42, Issue 3, June 2026.
AutoMark Index (AI) is a novel ablation algorithm that combines contact force, radiofrequency current, and application to provide real‐time lesion formation. AI‐guided CTI ablation protocol is efficient in shortening RF duration for acute bidirectional CTI block and CTI procedure time compared to the conventional 40 W ablation protocol.
Koji Sudo, Kenji Kuroki, Tetsuya Asakawa, Kazuya Nakagawa, Jumpei Saito, Chisa Asahina, Takeaki Goto, Maoko Atsumi, Tomoaki Hasegawa, Yasuteru Yamauchi, Kazutaka Aonuma, Akira Sato   +11 more
wiley   +1 more source