Results 181 to 190 of about 2,690,812 (395)

Actinorhodin Biosynthesis Terminates with an Unprecedented Biaryl Coupling Reaction

Angewandte Chemie, Volume 135, Issue 5, January 26, 2023., 2023
The last dimerization step of actinorhodin (ACT) biosynthesis was established through biochemical studies. ActVA‐ORF4 is a unique NAD(P)H‐dependent enzyme that catalyzes the biaryl‐coupling reaction using 8‐hydroxydihydrokalafungin (DHK‐OH) as the sole substrate. ActVA‐ORF3 is a quinone‐forming enzyme that forms DHK‐OH and ACT.
Makoto Hashimoto, Susumu Watari, Takaaki Taguchi, Kazuki Ishikawa, Takuya Kumamoto, Susumu Okamoto, Koji Ichinose   +6 more
wiley   +2 more sources

Temporal Dynamics of Microbial Communities in Anaerobic Digestion: Influence of Temperature and Feedstock Composition on Reactor Performance and Stability [PDF]

arXiv
Anaerobic digestion (AD) offers a sustainable biotechnology to recover resources from carbon-rich wastewater, such as food-processing wastewater. Despite crude wastewater characterisation, the impact of detailed chemical fingerprinting on AD remains underexplored.
arxiv  

Multidimensional Engineering of Escherichia coli for Efficient Adipic Acid Synthesis From Cyclohexane

Advanced Science, EarlyView.
An engineered Escherichia coli is developed to efficiently produce adipic acid (AA) from cyclohexanol, KA oil (a mixture of cyclohexanol and cyclohexanone), or cyclohexane through a combination of enzyme screening, protein fusion, and genome editing techniques. This approach has achieved the highest recorded productivity for biological AA production to
Fei Wang, Huiqi Sun, Di Deng, Yuanqing Wu, Jing Zhao, Qian Li, Aitao Li   +6 more
wiley   +1 more source

Black tea water kefir beverage : a thesis submitted in partial fulfilment of the requirement for the degree of Master of Food Technology, Massey University, Albany, New Zealand [PDF]

, 2017
Fermented foods and beverages play an important role in the human diet as they provide essential nutrients as well as contribute towards prevention of diseases.
Subardjo, Maria Vina Kania
core  

Orally Administered Functional Polyphenol‐Nanozyme‐Armored Probiotics for Enhanced Amelioration of Intestinal Inflammation and Microbiota Dysbiosis

Advanced Science, EarlyView.
This study presents a novel polyphenol‐nanozyme‐armored probiotic system (ECA@EcN) for enhanced treatment of inflammatory bowel disease (IBD). By integrating chitosan‐modified epigallocatechin gallate (EGCG‐CS) with gold nanozymes, the system effectively scavenges ROS, improves probiotic viability, and restores gut microbiota balance.
Yong Zhu, Ziqu Fang, Jie Bai, Longhui Wang, Jiaqing Chen, Zehua Zhang, Qiang Wang, Weiwei Sheng, Xueyin Pan, Zhenyuan Gao, Dengqiu Xu, Pengkai Wu, Beicheng Sun   +12 more
wiley   +1 more source

Cultivating Precision: Comparative Analysis of Sensor-Based Yogurt Fermentation Monitoring Techniques [PDF]

arXiv
Fermented dairy products, including yogurt, are widely consumed for their nutritional and health benefits. While numerous methods exist to monitor and understand yogurt fermentation, the literature lacks an integrated evaluation of diverse sensing approaches within a single experimental framework. To address this gap, this study systematically examines
arxiv  

High Fat Low Carbohydrate Diet Is Linked to CNS Autoimmunity Protection

Advanced Science, EarlyView.
Mapping global epidemiological data to macronutrient supply reveals high carbohydrate, in contrast to high fat supply, associates with increased multiple sclerosis (MS) prevalence and incidence. This is confirmed in a mouse MS model, experimental autoimmune encephalomyelitis (EAE), using isocaloric diets: a high carbohydrate diet aggravates, a high ...
Duan Ni, Jian Tan, Julen Reyes, Alistair M Senior, Caitlin Andrews, Jemma Taitz, Camille Potier‐Villette, Claire Wishart, Alanna Spiteri, Laura Piccio, Nicholas Jonathan Cole King, Romain Barrès, David Raubenheimer, Stephen James Simpson, Ralph Nanan, Laurence Macia   +15 more
wiley   +1 more source

Cell Sizes Matter for Industrial Bioproduction, a Case of Polyhydroxybutyrate

Advanced Science, EarlyView.
Most bacterial cells are small, restricting the accumulation of intracellular products like polyhydroxyalkanoates (PHA). To solve this problem, the ClpXP system in Halomonas bluephagenesis is identified and redesigned. Then MreB is degraded progressively by this engineered system, expanding cell size more than nine times.
Yi‐Ling Chen, Xu Liu, Li‐Zhan Zhang, Ji‐Shuai Yang, Wei‐Ke Guo, Shuang Zheng, Jia‐Le Wang, Fu‐Qing Wu, Xu Yan, Qiong Wu, Guo‐Qiang Chen   +10 more
wiley   +1 more source

Metabolic Engineering of Corynebacterium glutamicum for High‐Level Production of 1,5‐Pentanediol, a C5 Diol Platform Chemical

Advanced Science, EarlyView.
This study develops an efficient biosynthesis system for 1,5‐pentanediol (1,5‐PDO) in Corynebacterium glutamicum, an important compound for industrial applications. By engineering the l‐lysine degradation pathway, 5‐hydroxyvaleric acid (5‐HV) is synthesized from glucose as a key intermediate.
Yu Jung Sohn, Se‐Yeun Hwang, Haeyoung Lee, Subeen Jeon, Ji Young Park, Jaehyung Kim, Donghyuk Kim, Ki Jun Jeong, Sang Yup Lee, Jeong Chan Joo, Jin‐Byung Park, Si Jae Park   +11 more
wiley   +1 more source

Advances in Fecal Microbiota Transplantation for Gut Dysbiosis‐Related Diseases

Advanced Science, EarlyView.
This article reviews the use of fecal microbiota transplantation (FMT) to treat intestinal diseases like recurrent Clostridioides difficile infection (rCDI), inflammatory bowel disease (IBD), and irritable bowel syndrome (IBS). It discusses FMT's efficacy, influencing factors such as donor selection, recipient characteristics, and treatment protocols ...
Shuna Hou, Jiachen Yu, Yongshuang Li, Duoyi Zhao, Zhiyu Zhang   +4 more
wiley   +1 more source