Results 201 to 210 of about 160,357 (349)
This study explores honeysuckle‐derived nanovesicles (HNVs) for treating inflammatory bowel disease. Orally administered HNVs alleviates colitis in mice by repairing the gut barrier, reducing inflammation, and restoring a healthy gut microbiota.
Yuanyuan Wang +11 more
wiley +1 more source
Improvement in Smoothness of Fermented Soymilk Yogurt-Mimic by Effective Use of Applicable Lactic Acid Bacteria Strains. [PDF]
Fu W, Kobayashi A, Yano H.
europepmc +1 more source
A fecal microbial meta‐analysis reveals that Megasphaera is highly abundant in the Asian population with IBD and CRC. M. elsdenii reshapes colonic immunity by triggering DC cell‐mediated Th1 and Th17 inflammation. M. elsdenii and M. elsdenii‐enriched microbiota exacerbate colonic inflammation and tumorigenesis in AOM/DSS mice.
Xinxin Hou +9 more
wiley +1 more source
In temporal lobe epilepsy, hippocampal APOE is markedly upregulated predominantly in microglia. APOE overexpression in microglia drives TLR4 and cGAS/STING‐dependent neuroinflammation, engages bidirectional crosstalk with neurons and astrocytes, increases neuronal excitability, and perturbs hippocampal lipid metabolism. These findings suggest that APOE‐
Jianwei Shi +10 more
wiley +1 more source
Safety evaluation of the food enzyme d-psicose 3-epimerase from the genetically modified <i>Escherichia coli</i> strain K-12 W3110-TKO CDX-088. [PDF]
EFSA Panel on Food Enzymes (FEZ) +16 more
europepmc +1 more source
Molecular Chain Elongation Mechanism for n‐Caproate Biosynthesis by Megasphaera Hexanoica
The medium‐chain carboxylate‐producing microbe Megasphaera hexanoica is analyzed through genomics, transcriptomics, and metabolic engineering. The n‐caproate biosynthetic pathway is reconstructed in Escherichia coli, highlighting MhTHL as a key β‐ketothiolase. Structural analysis and mutagenesis reveal that MhTHL has a distinct substrate‐binding pocket,
Byoung Seung Jeon +8 more
wiley +1 more source
Application of Probiotics in Foods: A Comprehensive Review of Benefits, Challenges, and Future Perspectives. [PDF]
Grujović MŽ +2 more
europepmc +1 more source

