Results 171 to 180 of about 2,478,172 (300)

Engineering <i>Escherichia coli</i> for Ergothioneine Production via Metabolic Engineering and Fermentation Optimization. [PDF]

Microorganisms
Liu Y, Wen Y, Hu R, Han R, Liu D, Zhang H.   +5 more
europepmc   +1 more source

Adhesion‐Enhanced Engineered Probiotic for Prolonged Intestinal Retention and Calprotectin‐Responsive IBD Therapy

Advanced Science, EarlyView.
An intelligent engineered probiotic platform is developed for the precision management of inflammatory bowel disease. By integrating surface‐displayed adhesins with an inflammation‐responsive CAT‐SOD‐GPx tripartite fusion system and mucosal repair factors, this programmable system achieves prolonged intestinal retention and multi‐pronged therapy.
Yuxi Wang, Peichao Zhang, Simin Gu, Hongyun Lu, Ningning Jiang, Jiarun Zhao, Enbo Xu, Xiayu Liu, Ying Shi, Qihe Chen   +9 more
wiley   +1 more source

Systematic optimization of <i>Komagataella phaffii</i> (Pichia pastoris) for high-efficiency recombinant protein production: Advancements in strain engineering, fermentation optimization, and AI-driven technologies. [PDF]

Eng Microbiol
Huang Y, Wang J, Wang A, Zheng L, Lin Y, Liang S.   +5 more
europepmc   +1 more source

A Review on the Application of Near-Infrared Technology for Monitoring and Control of Food Fermentation Process

The optimization and control of the food fermentation process, which are vital for consistent product quality, are often hindered by the limitations of conventional analytical methods.
Chenyu Yang, Jia Song, Min Wang, Bingning Gao, Ao Zhang, Chao Yu, Yanhua Liu, Mengting Yu, Xu Yang, Jianye Xia, Yu Zheng   +10 more
core   +1 more source

A Metabolic‐Epigenetic Axis of AARS1/IGF2BP3‐K280 Lactylation Sustains Endometrial Cancer Stemness and Recurrence

Advanced Science, EarlyView.
Lactate‐driven endometrial cancer relapse is mediated by enzymatic protein modification. Elevated lactate levels activate AARS1, which catalyzes K280 lactylation of IGF2BP3, therefore stabilizing HMGA2 mRNA and promoting tumor stemness and recurrence.
Peng Jiang, Yunfeng Zheng, Chenfan Tian, Yuan Tu, Xiaoxia Chang, Jiaxin Yu, Hangkun Yu, Chunxia Gong, Jie Xiong, Philip N. Baker, Yong Fu, Chao Tong   +11 more
wiley   +1 more source

Development of lotus seed-based vegan yogurt: fermentation optimization, quality evaluation and analysis of key bioactive alkaloids. [PDF]

Front Nutr
Chi M, Wu W, Wu Y, Hu J, Zheng B, Zeng S, Lin S.   +6 more
europepmc   +1 more source

Multi‐Tissue Crosstalk Regulating Meniscus Healing Under Inflammation and Physiological Loading

Advanced Science, EarlyView.
Using a novel Meniscus‐on‐a‐chip (MoC) model integrated with a meniscus‐specific bioreactor, this study investigated the roles of multi‐tissue crosstalk that regulates injury, healing, and degeneration of the meniscus injury under inflammation and pathophysiological loading.
Hun Jin Jeong, Elen Zhu, Min Seo Kang, Ming Wang, Sam Comito, Chang H. Lee   +5 more
wiley   +1 more source

Toward Sustainable Xanthan Gum Production: Waste-Derived Substrates, Fermentation Optimization, and Eco-Friendly Extraction Approaches. [PDF]

Foods
Abdul PM, Kurniawan SB, Rohani R, Said NSM, Roslan R, Imron MF.   +5 more
europepmc   +1 more source

Magnetically Guided Macrophage Immunobots Coordinate Iron‐Metabolic Cascades and Immunogenic Ferroptosis for Tumor Immunotherapy

Advanced Science, EarlyView.
Magnetically guided macrophage immunobots integrate active tumor targeting with immunometabolic therapy. After systemic administration, magnetic actuation enhances immunobot retention and tumor penetration, while LPS‐functionalized FePt microrollers sustain M1‐like polarization through inflammatory and iron‐amplified oxidative signaling and trigger ...
Xirui Zeng, Yingfei Zhang, Chong Wu, Qijia Duan, Mengqi Fan, Kuan Wang, Shirong Cai, Immihan Ceren Yasa   +7 more
wiley   +1 more source

Enhancing Astaxanthin Production in <i>Paracoccus marcusii</i> Using an Integrated Strategy: Breeding a Novel Mutant and Fermentation Optimization. [PDF]

Mar Drugs
Li Y, Huang S, Wei D, Pan S.
europepmc   +1 more source