Whole-Cell Production of Patchouli Oil Sesquiterpenes in Escherichia coli: Metabolic Engineering and Fermentation Optimization in Solid-Liquid Phase Partitioning Cultivation. [PDF]
ACS Omega, 2020 Aguilar F +3 more
europepmc +1 more source
Endowing Flexibility of Alveolar Type II Cells to Recapitulate Development From Lung Bud to Alveoli
Advanced Science, EarlyView.Adult human alveolar type 2 cells are chemically reprogrammed into expandable alveolar progenitor‐like cells that acquire bud tip‐like features during expansion and form organoids that mature into alveolar‐like structures. These organoids model influenza A virus infection and innate immune responses in vitro, while transplanted cells engraft ...
Hongqian Ma +18 more
wiley +1 more source
Rumen microbial fermentations and their optimization
, 1994 Enzymes in the digestive tract of ruminants are unable to digest roughages whereas rumen microbes actively degrade and ferment them. Microbes transform dietary organic matter in volatile fatty acids which supply the major supply of energy to animals. Microbial proteins synthetized into the rumen are then digested into the small intestine where they are
openaire +1 more source
Designing Spoonable Milk Kefir Gels: From Fermentation Optimization to Clean-Label Gel Structuring with Psyllium. [PDF]
GelsCardenete-Fernández M +4 more
europepmc +1 more source
Fermentation optimization and disease suppression ability of a Streptomyces ma. FS-4 from banana rhizosphere soil. [PDF]
BMC Microbiol, 2020 Duan Y +6 more
europepmc +1 more source
Advanced Science, EarlyView.A multi‐level analytical framework, integrating protein‐level persistence analysis, nontargeted HRMS formula tracking, peptide‐level proteomics, and targeted monomer quantification under varying redox conditions, together with FMO calculations reveal that ammonification is limited by medium molecular weight nitrogenous multimers.
Jing Li +4 more
wiley +1 more source
Predicting Enzyme Turnover Numbers and Enabling Rational Enzyme Evolution
Advanced Science, EarlyView.MCKcat, a deep learning framework combining multi‐scale convolution and cross‐attention, accurately predicts enzyme turnover number (kcat) by fusing sequence and reaction representations. It couples with rational design in a two‐step strategy for Bacillus aryabhattai laccase engineering, achieving a 75% positive rate with synergistically enhanced ...
Fengya Ge +6 more
wiley +1 more source
Combinatorial mutagenesis and fermentation optimization biotechnologies synergistically enhance monacolin K content in functional red yeast rice. [PDF]
Front MicrobiolWu Z +7 more
europepmc +1 more source
Advanced Science, EarlyView.The multilayer fiber‐based PGC sensor, fabricated via graphene‐mediated electroless copper deposition, demonstrates high sensitivity, mechanical durability, and fast response speed. Additionally, it features low‐temperature thermal assisted recovery and thermal resistance, providing a promising platform for wearable electronic devices and IoT ...
ByungJun Kim +5 more
wiley +1 more source