Results 201 to 210 of about 7,838,334 (308)

Effects of ensiling temperature on fermentation quality, enzyme activities, and metabolomic profiles in Pediococcus acidilactici L10-inoculated native grass silage. [PDF]

BMC Plant Biol
Zhu, Yan Y, Bao J, Zhao M, Wang Z, Sun P, Yan X, Liu M, Su R, Ge G.   +9 more
europepmc   +1 more source

Autophagy Orchestrates Anti‐Tumor Immunity to Enhance Chemosensitivity via the FBXW2/C/EBPβ/TIMP‐2 Axis in Colorectal Cancer

Advanced Science, EarlyView.
Chemotherapy leverages tumor‐cell autophagy to reshape the colorectal cancer immune microenvironment. Autophagy degrades FBXW2 to promote C/EBPβ‐mediated TIMP‐2 transcription and MMP‐9 suppression, driving intra‐tumoral CD8+ T‐cell infiltration. Targeting MMP‐2/9 or restoring TIMP‐2 overcomes chemo‐resistance in autophagy‐deficient tumors. ABSTRACT The
Bing Cheng, Chaoying Wei, Zhitong Niu, Jinxin Chen, Guojie Long, Yingzhen Weng, Qiufeng Liu, Yue Jiang, Panpan Wang, Ronghua Zhang, Qiang Yu, Xiaojian Wu, Wenyu Wang   +12 more
wiley   +1 more source

Characterization of Flavor Profiles of Cigar Tobacco Leaves Grown in China via Headspace–Gas Chromatography–Ion Mobility Spectrometry Coupled with Multivariate Analysis and Sensory Evaluation

ACS Omega
Beibei Zhu, Hongyue An, Li Li, Hongfei Zhang, Jinxiong Lv, Wanrong Hu, Fang Xue, Lulu Liu, Shengbao He, Dongliang Li   +9 more
doaj   +1 more source

Fermentation quality, microbial dynamics, and rumen degradability of total mixed ration silages containing Manihot sp' foliage. [PDF]

Trop Anim Health Prod
de Sousa AR, de Araújo MJ, Medeiros OT, Dias-Silva TP, Gurgel ALC, de Souza Miranda R, Bezerra LR, Ítavo LCV, Difante GDS, Edvan RL.   +9 more
europepmc   +1 more source

CHST1 Drives Immunotherapy Resistance in Triple‐Negative Breast Cancer by Orchestrating an Immunosuppressive Microenvironment via the NKRF–CCL20–Macrophage Axis

Advanced Science, EarlyView.
Proposed model of CHST1‐associated immune remodeling in triple‐negative breast cancer. In CHST1‐low tumors, greater nuclear accumulation of NKRF is associated with repression of an NF‐κB‐related CCL20 transcriptional program and an immune‐inflamed microenvironment.
Shu‐Hao Jiang, Xiao‐Han Ying, Ruo‐Qing Wang, Qun Zhang, Li Chen, Zhi‐Ming Shao, Jun‐Jie Li   +6 more
wiley   +1 more source

Composite Microbial Solid-State Fermentation Enhances the Fermentation Quality, Nutritional Value, and Safety of Cottonseed Hulls: Insights Based on Physicochemical Detection and Untargeted Metabolomics. [PDF]

Microorganisms
Yang H, Zhou X, Ying Y, Liu Y, Yishake H, Li H, Wang C.   +6 more
europepmc   +1 more source

An Engineered HR1‐Stem Helix‐HR2 Trimeric Platform for Developing Broad‐Spectrum Coronavirus Vaccines

Advanced Science, EarlyView.
Sun et al. report a self‐assembling trimeric subunit vaccine platform termed RHS, which integrates the JN.1 receptor‐binding domain (RBD) with the heptad repeat 1 (HR1), stem helix (SH), and heptad repeat 2 (HR2) regions. The SARS‐CoV‐2 RHS vaccine elicits variant‐reactive RBD‐specific antibodies and cross‐reactive SH‐specific antibodies against ...
Xikui Sun, Junhao Fan, Xiaolu Xie, Yuting Shi, Xiaoqing Liu, Tiefeng Xu, Sidi Yang, Keda Shi, Chengshu Xie, Shixiong Li, Siwen Chen, Ruoxi Cai, Ping He, Yuzhen Ye, Tao Chen, Xiancai Ma, Chunmei Li, Jingyou Yu, Deyin Guo   +18 more
wiley   +1 more source

Geographic and Climatic Effects on Fermentation Quality and Bacterial Diversity of <i>Saccharum arundinaceum</i> and <i>Leucaena leucocephala</i> Silage. [PDF]

Microorganisms
Wu S, Liu Y, Chen D, Li M, Zi X.
europepmc   +1 more source

The Effect of Ligand Reactivity and Carrier Mechanics on Thiol‐Mediated Cellular Uptake for miRNA Nano‐Drugs

Advanced Science, EarlyView.
The effect of ligand reactivity and carrier mechanics on thiol‐mediated uptake was investigated at the single‐molecule/particle level. The interaction kinetics of LA and AspA with membrane thiols were quantified; AspA is more efficient due to the higher binding affinity, greater binding stability, and more double‐disulfide binding, as well as greater ...
Zhuang Zhang, Hui Wang, Hao Zhang, Zhenkuan Cao, Zehui Liu, Siying Li, Hongda Wang, Yuping Shan   +7 more
wiley   +1 more source

Effects of Ensiling Duration on Fermentation Quality and Bacterial Communities of Fermented Total Mixed Ration Formulated with Corn Stalk and Broom Sorghum Straw. [PDF]

Microorganisms
Zhao J, Zou Y, Bao J, Sun P, Liu M, Bai B, Liu X, Wang Y, Du S, Zhao M.   +9 more
europepmc   +1 more source