EGR1 Promotes Craniofacial Bone Regeneration via Activation of ALPL⁺PDGFD⁺ Periosteal Stem Cells
ALPL+PDGFD+ (AP+) cells are distinct calvarial periosteal stem cells (PeSCs) with diminished postnatal activity. EGR1 drives PeSCs development via BMP signaling through its Znf2 domain and activates them via CTNNB1/WNT10B signaling through its Znf2/3 domains.
Yang Li+15 more
wiley +1 more source
The impact of fangxian huangjiu on the fermentation quality and microbial community dynamics of cigar wrapper leaves. [PDF]
Yao L+6 more
europepmc +1 more source
CTSK plays a critical role in pulmonary fibrosis. Excessive CTSK accumulation interacts with SNX9 to enhance TGF‐β1‐induced SMAD3 activation and GLS1 expression in fibroblasts, driving glutamine metabolism for collagen biosynthesis and exacerbating pulmonary fibrosis.
Mengting Chen+10 more
wiley +1 more source
The potential of biogas production and effects of alfalfa silage under the synergistic influence of <i>Lactobacillus acidophilus</i> and <i>Rosa roxburghii</i> pomace waste on the fermentation quality and bacterial community. [PDF]
Li M+11 more
europepmc +1 more source
<b>Interaction of <i>Saccharomyces cerevisiae</i> and <i>Lactococcus lactis</i> in the fermentation and quality of artisanal cachaça [PDF]
Fernanda Paula Carvalho+4 more
openalex +1 more source
The bottom‐up strategy based on multiomics data is used for the SynCom design, and it successfully inhibited F. nucleatum growth and achieved stable colonization in vivo. In addition, it promoted tryptophan metabolism and secondary bile acid conversion, reduced lipid accumulation, relieved microbiome disorder, decreased inflammatory reaction, and ...
Zhongkun Zhou+11 more
wiley +1 more source
Effects of different additives on fermentation quality, mycotoxin concentrations, and microbial communities in high-moisture corn kernels during wet storage. [PDF]
Wang X+6 more
europepmc +1 more source
This study investigates hypoglycemia‐induced diabetic macrovascular endothelial dysfunction. It reveals that hypoglycemia triggers ZBP1‐dependent PANoptosis of endothelial cells, proinflammatory polarization of macrophages, and fibrosis of vascular smooth muscle cells (VSMCs) in diabetic mice.
Deyu Zuo+10 more
wiley +1 more source