Results 111 to 120 of about 226,434 (342)

A Nonviral Neo‐Nucleocapsid for Cell‐Specific RNA Delivery Developed by Pseudo‐Cyclic Peptide Grafting and Directed Evolution

Angewandte Chemie, EarlyView.
Nonviral neo‐nucleocapsids developed from a repurposed bacterial protein cage, and macrocyclic peptide pharmacophores via protein‐protein ligation, bacteria‐based directed evolution, lasso‐grafting, and mammalian cell‐based directed evolution enabled cell specific RNA delivery.
Daiki Kanayama, Naohiro Terasaka, Kazuki Kato, Sae Okazaki, Hiroaki Suga   +4 more
wiley   +2 more sources

Transient overexpression of human H- and L-ferritin chains in COS cells [PDF]

, 1998
Barbara Corsi, Federica Perrone, Monique Bourgeois, Carole Beaumont, C. Panzeri, Anna Cozzi, Romina Sangregorio, Paolo Santambrogio, Alberto Albertini, Paolo Arosio, Sonia Levi   +10 more
openalex   +1 more source

A Prussian Blue Nanozyme‐Adjuvanted Vaccine Presenting Phosphocholine Antigens for Induction of Immunotolerance in Inflammatory Bowel Disease

Advanced Science, EarlyView.
ABSTRACT Inflammatory bowel disease (IBD) is a complex disorder characterized by chronic intestinal inflammation and impaired barrier function, for which effective long‐term therapies remain elusive. To address this challenge, we developed a novel nano‐vaccine that combines Prussian blue nanozymes (PBNZs) adjuvants with a ferritin carrier loaded with ...
Jingyi Sheng, Yubo Huang, Xinyue Li, Yin Liu, Yuehuang Wu, Yuxin Zhang, Ning Gu   +6 more
wiley   +1 more source

Unnatural Amino Acid and Emerging Chemistry Approaches to Map RNA–Protein Interactions

Angewandte Chemie, EarlyView.
This review highlights emerging chemistries for mapping RNA–protein interactions, including genetically encoded unnatural amino acids, novel photocrosslinkers, and non‐photoactivatable crosslinking systems. We compare their mechanisms, reactivity and applications, outlining how these next‐generation tools enable higher‐resolution, site‐specific ...
Eryn Lundrigan, Parrish Evers, Elexa Scott, John Paul Pezacki   +3 more
wiley   +2 more sources

Lactylation Reprogramming in the Bone Infection Microenvironment Identifies PGK1 K361 as a Potential Therapeutic Target for Osteogenic Dysfunction

Advanced Science, EarlyView.
Staphylococcus aureus (S. aureus) infection creates a high‐lactate microenvironment, promoting p300‐mediated lactylation of PGK1 at lysine 361 (K361). Lactylated PGK1 translocates to the mitochondrial outer membrane and interacts with VDAC3. This interaction triggers FtMt downregulation, iron accumulation, and excessive PINK1/Parkin‐mediated mitophagy,
Han‐jun Qin, Si‐ying He, Ting‐hui Xiao, Da‐mao Dai, Xin‐jia Hu, Nan Jiang   +5 more
wiley   +1 more source

Longitudinal neural connection detection using a ferritin‐encoding adeno‐associated virus vector and in vivo MRI method

, 2021
Aoling Cai, Ning Zheng, Garth J. Thompson, Yang Wu, Binbin Nie, Kunzhang Lin, Peng Su, Jinfeng Wu, Anne Manyande, Ling‐Qiang Zhu, Jie Wang, Fuqiang Xu   +11 more
openalex   +1 more source

Serum Vitamin B12, Folate, and Ferritin levels in Children and Adolescents with Anxiety Disorders; Controlled Study

, 2022
Sabide Duygu Uygun, Zeynep Göker, Fatma Karaca Kara, Özden Şükran Üneri   +3 more
openalex   +1 more source

Hetrombopag Added to Cyclosporine as the First‐Line Treatment for Patients With Non‐Severe Aplastic Anemia: A Phase 2 Multicenter Trial

American Journal of Hematology, EarlyView.
ABSTRACT Non‐severe aplastic anemia (NSAA) is a heterogeneous bone marrow failure syndrome with limited standardized treatment options. Cyclosporine A (CsA) monotherapy often yields suboptimal responses, highlighting an unmet clinical need for more effective therapies.
Lele Zhang, Ruonan Li, Qian Liang, Weiwang Li, Hong Pan, Zhen Gao, Liwei Fang, Jingyu Zhao, Xiao Yu, Zhexiang Kuang, Neng Nie, Jianping Li, Jinbo Huang, Xin Zhao, Meili Ge, Yizhou Zheng, Jun Li, Hong Zhang, Jun Shi   +18 more
wiley   +1 more source

Ferromagnetism in two mouse tumours [PDF]

, 1982
A variety of living organisms has been found recently that are biochemically able to precipitate the ferromagnetic mineral magnetite (Fe3O4). Originally discovered in the radular teeth of a primitive marine mollusc (Lowenstam, 1962), magnetite has since ...
Batkin, Stanley, Kirschvink, Joseph L., Tabrah, Frank L.   +2 more
core  

H‐ferritin expression in astrocytes is necessary for proper oligodendrocyte development and myelination [PDF]

, 2021
Verónica T. Cheli, Diara A. Santiago González, Qiuchen Wan, Giancarlo Denaroso, Rensheng Wan, Shaina L. Rosenblum, Pablo M. Paez   +6 more
openalex   +1 more source