Results 121 to 130 of about 286,555 (389)

Advanced Therapeutic Approach Based on LDHs–Mimetic Oxidoreductase

Advanced Science, EarlyView.
Overview of Sructure, Multienzyme‐mimicking Activity and Advanced Therapeutic Approach Based on LDHs–Mimetic Oxidoreductase. Abstract Redox dysregulation is recognized as a key driver in the pathophysiology of numerous refractory diseases, contributing significantly to the progression and poor prognosis.
Kai Song, Yu Wei, Peng Jia, Shan He, Qian Wang, Manman Xu, Hongzhi Liu, Pengtao Bao, Shanyue Guan, Xiaozhong Qu   +9 more
wiley   +1 more source

A SARS-CoV-2 spike ferritin nanoparticle vaccine protects hamsters against Alpha and Beta virus variant challenge [PDF]

, 2021
Kathryn McGuckin Wuertz, Erica K. Barkei, Wei‐Hung Chen, Elizabeth J. Martinez, Inès Lakhal-Naouar, Linda L. Jagodzinski, Dominic Paquin‐Proulx, Gregory D. Gromowski, Isabella Swafford, Akshaya Ganesh, Ming Dong, Xiankun Zeng, Paul V. Thomas, Rajeshwer S. Sankhala, Agnes Hajduczki, Caroline E. Peterson, Caitlin Kuklis, Sandrine Soman, Lindsay Wieczorek, Michelle Zemil, Alexander Anderson, Janice M. Darden, Heather Hernandez, Hannah Grove, Vincent Dussupt, Holly R. Hack, Rafael De La Barrera, Stasya Zarling, James F. Wood, Jeffrey W. Froude, Matthew Gagné, Amy R. Henry, Elham Bayat Mokhtari, Prakriti Mudvari, Shelly J. Krebs, Andrew Pekosz, Jeffrey R. Currier, Swagata Kar, Maciel Porto, Adrienne Winn, Kamil Radzyminski, Mark G. Lewis, Sandhya Vasan, Mehul S. Suthar, Victoria R. Polonis, Gary R. Matyas, Eli Boritz, Daniel C. Douek, Robert A. Seder, Sharon P. Daye, Mangala Rao, Sheila A. Peel, Michael Joyce, Diane L. Bolton, Nelson L. Michael, Kayvon Modjarrad   +55 more
openalex   +1 more source

Migrasomes in Ischemic Stroke: Molecular Landscape and Pathophysiological Impact

Advanced Science, EarlyView.
Multi‐omics profiling of stroke patients exposes systemic molecular fingerprints of immune activation, oxidative stress and metabolic collapse. Complement and coagulation cascade, and cholesterol metabolism emerge as shared functional hallmarks of plasma migrasomes in stroke patients and migrasomes isolated from experimental stroke mice.
Huifen Zhou, Yingying Zhang, Peng Zhou, Haofang Wan, Lingling Li, Bin Xu, Yuping Wan, Yingming Song, Yi Kang, Hongbo Zhang, Min Shi, Qun Hou, Jiehong Yang, Chen Ding, Wei Fu, Buchang Zhao, Haitong Wan   +16 more
wiley   +1 more source

Randomized trial comparing proactive, high-dose versus reactive, low-dose intravenous iron supplementation in hemodialysis (PIVOTAL) : Study design and baseline data [PDF]

, 2018
Background: Intravenous (IV) iron supplementation is a standard maintenance treatment for hemodialysis (HD) patients, but the optimum dosing regimen is unknown.
Anker, Stefan D., Bhandari, Sunil, Farrington, Kenneth, Ford, Ian, Kalra, Philip A., Macdougall, Iain C., McMurray, John J.V., Murray, Heather, Steenkamp, Retha, Tomson, Charles R.V., Wheeler, David C., White, Claire, Winearls, Christopher G.   +12 more
core   +4 more sources

A SARS-CoV-2 Spike Ferritin Nanoparticle Vaccine Is Protective and Promotes a Strong Immunological Response in the Cynomolgus Macaque Coronavirus Disease 2019 (COVID-19) Model [PDF]

, 2022
Sara C. Johnston, Keersten M. Ricks, Inès Lakhal-Naouar, Alexandra Jay, Caroline Subra, Jo Lynne Raymond, Hannah A. D. King, Franco Rossi, Tamara L. Clements, David P. Fetterer, Samantha Tostenson, Camila Macedo Cincotta, Holly R. Hack, Caitlin Kuklis, Sandrine Soman, Jocelyn King, Kristina K. Peachman, Dohoon Kim, Wei‐Hung Chen, Rajeshwer S. Sankhala, Elizabeth J. Martinez, Agnes Hajduczki, William C. Chang, Misook Choe, Paul V. Thomas, Caroline E. Peterson, Alexander Anderson, Isabella Swafford, Jeffrey R. Currier, Dominic Paquin‐Proulx, Linda L. Jagodzinski, Gary R. Matyas, Mangala Rao, Gregory D. Gromowski, Sheila A. Peel, Lauren E. White, Jeffrey M. Smith, Jay W. Hooper, Nelson L. Michael, Kayvon Modjarrad, Michael Joyce, Ayşegül Nalça, Diane L. Bolton, M. Louise M. Pitt   +43 more
openalex   +1 more source

Serum ferritin thresholds for the diagnosis of iron deficiency in pregnancy: a systematic review

Transfusion Medicine, 2017
The aim of this review was to understand the landscape of serum ferritin in diagnosing iron deficiency in the aetiology of anaemia in pregnancy. Iron deficiency in pregnancy is a major public health problem leading to the development of anaemia. Reducing
J. Daru, J. Allotey, J. P. Peña-Rosas, Khalid Khan   +3 more
semanticscholar   +1 more source

Identification of ferroptosis‐related genes involved in chronic obstructive pulmonary disease based on bioinformatics analysis

Animal Models and Experimental Medicine, EarlyView.
The design of the entire paper. Green part represents the bioinformatics analysis approach. Yellow part represents the ideas of animal experiment. Abstract Background Chronic obstructive pulmonary disease (COPD) is a type of chronic respiratory disease.
Xuejing Luan, Jinghui Xie, Lu Zhang, Xiao Ma, Lichangtian Jiao, Jie Zhu   +5 more
wiley   +1 more source

New approaches to treating chronic obstructive pulmonary disease with Colla corii asini

Animal Models and Experimental Medicine, EarlyView.
Colla corii asini improves chronic obstructive pulmonary disease (COPD) treatment through anti‐inflammatory, antioxidant, immune‐modulatory, and lung‐nourishing effects, addressing current therapeutic challenges via multitarget mechanisms. Abstract Chronic obstructive pulmonary disease (COPD) is one of the leading causes of death and disability ...
Wenchao Zhang, Siman Sun, Xiaoyu Fan, Jiuming He, Qing Li, Hongtao Jin   +5 more
wiley   +1 more source

Relationship of Ferritin Levels of Pregnant Women Who Had Fe Deficiency Anemia with Ferritin Levels and APGAR of the Neonates

Journal of Midwifery, 2018
Iron deficiency anemia in pregnant women can have a negative impact on the baby, such as placental development, low birth weight, prematurity, baby health, hypoxia, decreased immune status, possibility of having physiological disorders and infant growth.
Zuliyana Zuliyana, Yanwirasti Yanwirasti, Roza Sri Yanti   +2 more
doaj   +1 more source

Low glycosylated ferritin is a sensitive biomarker of severe COVID-19 [PDF]

, 2020
Maxime Fauter, Sébastien Viel, Sabine Zaepfel, Pierre Pradat, Julie Fiscus, Marine Villard, Lorna Garnier, Thierry Walzer, P. Sève, Thomas Henry, Yvan Jamilloux   +10 more
openalex   +1 more source