Results 31 to 40 of about 286,555 (389)

Ferritin nanovehicle for targeted delivery of cytochrome C to cancer cells [PDF]

, 2019
In this work, we have exploited the unique properties of a chimeric archaeal-human ferritin to encapsulate, deliver and release cytochrome c and induce apoptosis in a myeloid leukemia cell line.
Baiocco, P., Boffi, A., Bonamore, A., Fazi, F., Macone, A., Masciarelli, S., Palombarini, Federica, Quaglio, D., Trabuco, M. C.   +8 more
core   +2 more sources

Association between Serum Ferritin and Blood Lipids: Influence of Diabetes and hs-CRP Levels

Journal of Diabetes Research, 2020
This study is aimed at exploring the relationship between serum ferritin and blood lipids and the influence of diabetes and different hs-CRP levels. A total of 8163 subjects were analyzed.
Lianlong Yu, Jingyi Yan, Qian Zhang, Hong Lin, Lichao Zhu, Qiangqiang Liu, Changsheng Zhao   +6 more
doaj   +1 more source

Functionalization and Characterization of Magnetic Nanoparticles for the Detection of Ferritin Accumulation in Alzheimer's Disease [PDF]

, 2018
Early diagnosis in Alzheimer's disease (AD), prior to the appearance of marked clinical symptoms, is critical to prevent irreversible neuronal damage and neural malfunction that lead to dementia and death.
Cussó, Lorena, Desco, Manuel, Fernández Cabada, Tamara, Martínez Serrano, Alberto, Ramos Gómez, Milagros   +4 more
core   +1 more source

Ferritin in cancer therapy: A pleiotropic tumoraffin nanocage‐based transport

Cancer Medicine, 2023
Background Ferritin, a ubiquitously distributed iron storage protein, can specifically target tumor cells through transferrin receptor 1. Due to its rearrangeable nanocage structure, ferritin can be loaded with anticancer drugs.
Guodong Deng, Yang Li, Ning Liang, Pingping Hu, Yan Zhang, Lili Qiao, Yingying Zhang, Jian Xie, Hui Luo, Fei Wang, Fangjie Chen, Fengjun Liu, Deguo Xu, Jiandong Zhang   +13 more
doaj   +1 more source

Ferritins: furnishing proteins with iron [PDF]

, 2016
Ferritins are a superfamily of iron oxidation, storage and mineralization proteins found throughout the animal, plant, and microbial kingdoms. The majority of ferritins consist of 24 subunits that individually fold into 4-α-helix bundles and assemble in ...
A Crow, A Treffry, AG Frey, CC Philpott, DM Lawson, DM Lawson, E Wajnberg, EC Theil, EC Theil, EC Theil, EC Theil, EI Stiefel, ER Bauminger, F Barceló, F Bou-Abdallah, FA Fischbach, FA Fischbach, FH Kadir, FHA Kadir, GC Ford, GC Papaefthymiou, GD Watt, GD Watt, Geoffrey R. Moore, GR Moore, H Abdul-Tehrani, H Aitken-Rogers, H Shi, H Yao, H Yao, H Yao, J Yariv, J-F Ma, JD López-Castro, JD Mancias, JM Bradley, JM Bradley, JS Rohrer, Justin M. Bradley, L Swartz, L Toussaint, MA Quail, MJ O’Connell, ML Vasil, MR Cheesman, ND Chasteen, NE Brun Le, NE Brun Le, NE Brun Le, Nick E. Le Brun, NM Reid, O Sadeghi, P Arosio, P Doig, PD Hempstead, PL Ringeling, PM Harrison, PM Harrison, RF Boyer, RJ Ward, RK Behera, RP Garg, S Bereswill, S Granick, S Granick, S Levi, S Macedo, S Mann, S Mann, S Pfaffen, SC Andrews, SC Andrews, SG Wong, SK Weeratunga, T Asano, T Douglas, T Jones, T Tosha, TJ Stillman, TV O’Halloran, TZ Kidane, V Laufberger, VJ Wade, WH Massover, X Liu, X Yang, Y Ha, Y Wang, YH Pan   +88 more
core   +1 more source

Iron-based ferritin nanocore as a contrast agent [PDF]

, 2010
Self-assembling protein cages have been exploited as templates for nanoparticle synthesis. The ferritin molecule, a protein cage present in most living systems, stores excess soluble ferrous iron in the form of an insoluble ferric complex within its ...
Johnson, Eric, Lim, Sierin, Poh, Chueh Loo, Sana, Barindra, Sheah, Kenneth   +4 more
core   +2 more sources

Ferritin-based nanomedicine for disease treatment

Medical Review, 2023
Ferritin is an endogenous protein which is self-assembled by 24 subunits into a highly uniform nanocage structure. Due to the drug-encapsulating ability in the hollow inner cavity and abundant modification sites on the outer surface, ferritin nanocage ...
Zhu Yuanjun, Zhu Yuefeng, Cao Tianmiao, Liu Xiaoyu, Liu Xiaoyan, Yan Yi, Shi Yujie, Wang Jian-Cheng   +7 more
doaj   +1 more source

Enhanced Cellular Uptake of H-Chain Human Ferritin Containing Gold Nanoparticles

Pharmaceutics, 2021
Gold nanoparticles (AuNP) capped with biocompatible layers have functional optical, chemical, and biological properties as theranostic agents in biomedicine.
Italo Moglia, Margarita Santiago, Simon Guerrero, Mónica Soler, Alvaro Olivera-Nappa, Marcelo J. Kogan   +5 more
doaj   +1 more source

Increased Serum Levels of Hepcidin and Ferritin Are Associated with Severity of COVID-19

Medical Science Monitor, 2020
Background The aim of this study was to assess the diagnostic utility of iron homeostasis determinations for prediction of severity of COVID-19. Material/Methods This was a retrospective study enrolling a total of 50 patients diagnosed with the novel ...
Cuixing Zhou, Yimeng Chen, Yun Ji, Xiaozhou He, D. Xue   +4 more
semanticscholar   +1 more source

Salt-Dependent Aggregation and Assembly of -Expressed Ferritin

Dose-Response, 2016
Ferritin, with the primary function of iron storage, is a nearly ubiquitous protein found in most living organisms. Our recent investigations suggest that ferritin can assemble nanoparticles.
Wei Sun, Chengfeng Jiao, Yue Xiao, Luowei Wang, Cheng Yu, Jialin Liu, Yongli Yu, Liying Wang   +7 more
doaj   +1 more source