Results 71 to 80 of about 10,712 (297)

A new ferritin SjFer0 affecting the growth and development of Schistosoma japonicum

open access: yesParasites & Vectors, 2022
Background Schistosomiasis, an acute and chronic parasitic disease, causes substantial morbidity and mortality in tropical and subtropical regions of the world.
Fanyuan Zeng   +7 more
doaj   +1 more source

Evaluation of the Debye temperature for iron cores in human liver ferritin and its pharmaceutical analogue Ferrum Lek using Mossbauer spectroscopy [PDF]

open access: yes, 2014
An iron polymaltose complex Ferrum Lek used as antianemic drug and considered as a ferritin analogue and human liver ferritin were investigated in the temperature range from 295K to 90K by means of 57Fe Mossbauer spectroscopy with a high velocity ...
Alenkina, I. V.   +4 more
core   +1 more source

Magnetic Micro‐ and Nanorobots for Precision Thrombolysis: Design Strategies and Translational Challenges

open access: yesAdvanced Robotics Research, EarlyView.
Micro‐ and nanorobots for targeted thrombolysis. This perspective elaborates on the clinical indication of blood clot disorders and current limitations for treatment. As a novel, alternative solution, micro‐ and nanorobots can be used to treat and break down thrombi.
Joshua M. Mesfin   +3 more
wiley   +1 more source

Genetic predisposition to porto‐sinusoidal vascular disorder: A functional genomic‐based, multigenerational family study

open access: yesHepatology, EarlyView., 2022
A deleterious variant of FCHSD1 results in mTOR pathway overactivation and may cause porto‐sinusoidal vascular disorder (PSVD). The pedigree of the family demonstrated an autosomal dominant disease with variable expressivity. Whole‐genome sequencing and Sanger sequencing both validated the existence of the FCHSD1 variant and the heterozygosity of c ...
Jingxuan Shan   +19 more
wiley   +1 more source

Haemophagocytic lymphohistiocytosis in kidney transplant recipients

open access: yesIatreia, 2019
Hemophagocytic lymphohistiocytosis (HLH) in renal transplant recipients is a life-threatening hyper-inflammatory syndrome; associated with uncontrolled activation of cytotoxic T-lymphocytes and macrophages due to infections or immunosuppressive therapy ...
Nieto Ríos, John Fredy   +5 more
doaj   +1 more source

Pulmonary Haemosiderosis Secondary to Hereditary Haemochromatosis; a Case Report

open access: yesJournal of Cancer and Allied Specialties, 2020
Introduction: Hereditary haemochromatosis (HH) is an autosomal recessive disease of increased intestinal absorption of iron, leading to accumulation in tissues which may progress to organ damage, most commonly in the liver.
Waqas Jehangir   +2 more
doaj   +1 more source

Preparation and representation of recombinant Mn-ferritin flower-like spherical aggregates from marine invertebrates. [PDF]

open access: yesPLoS ONE, 2015
Ferritin has important functions in the transition and storage of toxic metal ions, but its regulation and function in many invertebrate species are still largely unknown.
Liping Chen   +6 more
doaj   +1 more source

Hepatic molecular conversion and detoxification of ferritin iron in adult lampreys (Geotria australis), following natural and induced iron loading [PDF]

open access: yes, 1995
Weekly intramuscular injections of 3 mg of iron as horse spleen ferritin into adult Geotria australis over 10 weeks, resulted in a progressive increase in that form of iron in the serum.
Harris, L.R.   +3 more
core   +1 more source

Integrated Transcriptomics Reveals Evolutionary Trajectories and Cell Density‐Dependent Mechanisms in Aldosterone‐Producing Adenomas

open access: yesAdvanced Science, EarlyView.
Aldosterone‐producing adenomas (APAs) develop via two distinct paths: directly from adrenal zona glomerulosa (zG) cells, or stepwise from zG cells through aldosterone‐producing micronodules (APMs) before progressing to APAs. Advanced single‐cell and spatial analyses identified distinct cell states linked to oxidative stress and cell–cell interactions ...
Zhuolun Sun   +7 more
wiley   +1 more source

Ferritin structure from Mycobacterium tuberculosis: comparative study with homologues identifies extended C-terminus involved in ferroxidase activity. [PDF]

open access: yesPLoS ONE, 2011
Ferritins are recognized as key players in the iron storage and detoxification processes. Iron acquisition in the case of pathogenic bacteria has long been established as an important virulence mechanism.
Garima Khare   +5 more
doaj   +1 more source

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