Results 141 to 150 of about 4,023 (167)
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2010
Regulatory factors affecting ferrochelatase activity were studied and an attempt was made to determine the role of ferrochelatase in the regulation of heme biosynthesis. Ferrochelatase was found to have a Km value of 0.105 mM for the porphyrin substrates, proto and mesoporphyrin IX and a Km value of 8.30 x 10⁻³ mM for ferrous ion, its metal substrate ...
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Regulatory factors affecting ferrochelatase activity were studied and an attempt was made to determine the role of ferrochelatase in the regulation of heme biosynthesis. Ferrochelatase was found to have a Km value of 0.105 mM for the porphyrin substrates, proto and mesoporphyrin IX and a Km value of 8.30 x 10⁻³ mM for ferrous ion, its metal substrate ...
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Deletion of the ferrochelatase gene in a patient with protoporphyria
Human Molecular Genetics, 19941697
Magness, Scott T. +6 more
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Regulation of ferrochelatase gene expression by hypoxia
Life Sciences, 2004Ferrochelatase (FECH), the last enzyme of the heme biosynthetic pathway, catalyzes the insertion of iron into protoporphyrin to form heme. This pathway provides heme for hemoglobin and other essential hemoproteins. The regulatory role of oxygen in the pathway has not been clearly established.
Yunying L, Liu +4 more
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Metal ion coordination sites in ferrochelatase
Coordination Chemistry Reviews, 2022Gloria C Ferreira, Gregory A Hunter
exaly
Small-molecule inhibitors of ferrochelatase are antiangiogenic agents
Cell Chemical Biology, 2022Sanha Lee +2 more
exaly
Structural and mechanistic basis of porphyrin metallation by ferrochelatase
Journal of Molecular Biology, 2000Salam Al-Karadaghi +2 more
exaly
Ferrochelatase in Saccharomyces cerevisiae
2020Rosine Labbe-Bois, Jean-Michel Camadro
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