Paving the way for precision medicine v2.0 in intensive care by profiling necroinflammation in biofluids [PDF]
, 2019 Current clinical diagnosis is typically based on a combination of approaches including clinical examination of the patient, clinical experience, physiologic and/or genetic parameters, high-tech diagnostic medical imaging, and an extended list of ...
Hoste, Eric, Vanden Berghe, Tom
core +2 more sources
Contribution of ferroptosis and GPX4’s dual functions to osteoarthritis progression
, 2022 Miao Yu +8 more
openalex +1 more source
A New Prognostic Risk Signature of Eight Ferroptosis-Related Genes in the Clear Cell Renal Cell Carcinoma [PDF]
, 2021 Ji Chen +10 more
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Deoxynivalenol Exposure Leads to Abnormal Renal Tubular Autophagy Flow
Advanced Science, EarlyView.DON exposure disrupts the initiation of renal autophagy by inhibiting the formation of autophagosomes, thereby impairing mitochondrial degradation. Damaged mitochondria increase oxidative stress, reduce ferroptosis resistance, and cause lysosomal Fe2⁺ accumulation, further disrupting autophagy.
Hao Chen, Xintong Zhou, Jun Ma
wiley +1 more source
Identification of a targeted ACSL4 inhibitor to treat ferroptosis-related diseases
Science AdvancesFerroptosis is a form of iron-dependent, lipid peroxidation–driven regulatory cell death that has been implicated in the pathogenesis of multiple diseases, including organ injury, ischemia/reperfusion, and neurodegenerative diseases.
Qian Huang +10 more
semanticscholar +1 more source
Arbutin alleviates fatty liver by inhibiting ferroptosis via FTO/SLC7A11 pathway
, 2023 Tianyu Jiang +15 more
openalex +1 more source
Advanced Science, EarlyView.Dual‐stimuli‐responsive CuFeTe2 nanosheets (CFT) induce cuproptosis/ferroptosis via TME‐responsive Fe2⁺/Cu2⁺ release and NIR‐II photothermal effects, amplifying ROS and depleting HSP70/ATP to trigger ICD and immune activation, while ensuring biocompatible renal clearance for TNBC therapy.
Molin Liu +14 more
wiley +1 more source
Antiferroptosis therapy alleviated the development of atherosclerosis
MedCommFerroptosis has been confirmed to be associated with various diseases, but the relationship between ferroptosis and atherosclerosis (AS) remains unclear.
Zhou Yang +7 more
doaj +1 more source
ケミカルスクリーニングを駆使したオートファジー制御化合物の探索と、抗がん剤の薬効機序解析手法の確立 [PDF]
, 2018 筑波大学 (University of Tsukuba ...
Sano Osamu, 佐野 修
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Preferential Generation of 15-HETE-PE Induced by IL-13 Regulates Goblet Cell Differentiation in Human Airway Epithelial Cells [PDF]
, 2017 Type 2–associated goblet cell hyperplasia and mucus hypersecretion are well known features of asthma. 15-Lipoxygenase-1 (15LO1) is induced by the type 2 cytokine IL-13 in human airway epithelial cells (HAECs) in vitro and is increased in fresh asthmatic ...
Aldrovandi, Maceler +10 more
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