Results 171 to 180 of about 72,927 (343)
Ferroptosis and iron metabolism in diabetes: Pathogenesis, associated complications, and therapeutic implications [PDF]
Diabetes mellitus is a complex chronic disease, considered as one of the most common metabolic disorders worldwide, posing a major threat to global public health. Ferroptosis emerges as a novel mechanism of programmed cell death, distinct from apoptosis,
Gariani, Karim +5 more
core +1 more source
Advanced Science, EarlyView.The MOF material UIO‐66‐NH2 is functionalized with DBCO groups on its surface, encapsulating NO‐prednisolone and conjugating it with azide‐modified IL‐10. Finally, the complex is extruded with MM to form biomimetic functional nanoparticles. Upon intra‐articular injection, MI@UN, enveloped by the MM, specifically targets synovial macrophages, is ...
Wenwei Li +10 more
wiley +1 more source
Ferroptosis Contributes to Neuronal Death and Functional Outcome After Traumatic Brain Injury* [PDF]
, 2018 Elizabeth Kenny +10 more
openalex +1 more source
AGING MEDICINE, EarlyView.This article mainly introduces the pathologic process of sarcopenia and the recent progress in diagnosis and treatment, especially the nondrug treatment. ABSTRACT Sarcopenia refers to the progressive decline and wasting of skeletal muscle function, typically linked to aging or as a secondary effect of various conditions, including systemic inflammation,
Qi‐Fei Kuang +2 more
wiley +1 more source
Ferroptosis in cancer: from molecular mechanisms to therapeutic strategies
Signal Transduction and Targeted TherapyFerroptosis is a non-apoptotic form of regulated cell death characterized by the lethal accumulation of iron-dependent membrane-localized lipid peroxides.
Qian Zhou +9 more
doaj +1 more source
Development and Application of Organic Sonosensitizers in Cancer Therapy
Aggregate, EarlyView.This review provides a comprehensive overview of organic sonosensitizers employed in cancer treatment, describing their underlying mechanisms and structure‐activity relationship in terms of sonodynamic therapy. The significance of nanotechnology and combination therapy with other oncological modalities (photothermal therapy, photodynamic therapy, etc.)
Yuhan Ding +5 more
wiley +1 more source
Aggregate, EarlyView.Reported herein is the rational‐designed aggregation‐induced emission molecule (BPT), its nanoparticles (BPT NPs), and further processed heat and peroxynitrite generating nanoplatform for precision multimodal imaging‐guided tumor phototherapy. This nanoplatform showed near‐infrared II fluorescence, photothermal, and photoacoustic imaging capabilities ...
Ziyi Xu +14 more
wiley +1 more source
Optical Probes for Cellular Imaging of G‐quadruplexes: Beyond Fluorescence Intensity Probes
Angewandte Chemie, EarlyView.DNA and RNA can fold into tetra‐stranded helical structures known as G‐quadruplexes (G4s). There is mounting evidence suggesting that these structures have important biological roles. In this minireview we discuss advances in the design of optical probes for the detection of G4s that offer intensity‐independent readouts that address limitations of ...
Jenna Robinson +3 more
wiley +2 more sources
, 2018 Alejandra M. Martinez +4 more
openalex +1 more source