Results 231 to 240 of about 115,871 (339)

Plin4 modulates lipid droplet accumulation and ferroptosis in neurons exposed to benzo[a]pyrene. [PDF]

Cell Death Discov
Sun H, Ma Z, Guo X, Chen J, He H, Tong X, Ji T, Ding S, Zhou C, Lyu Y, Tian F, Zheng J.   +11 more
europepmc   +1 more source

Hypoxia‐Induced PRMT1 Lactylation Drives Vimentin Arginine Asymmetric Dimethylation in Tumor Metastasis

Advanced Science, EarlyView.
Hypoxia triggers lactylation of PRMT1 at K134/K145, enhancing its methyltransferase activity to asymmetrically dimethylate vimentin R64. This post‐translational cascade promotes vimentin filament assembly, cytoskeletal remodeling, and tumor metastasis, with PRMT1 inhibition (MS023) reducing metastatic colonization.
Jia Zhou, Shuying Qiu, Xia Yang, Yan Wu, Xinxia Yao, Hangqi Hu, Jingfeng Luo, Chandra Sugiarto Wijaya, Lingfeng Ma, Xiaojun Long, Lingna Xu, Jinquan Liu, Chaoqun Wang, Yibin Pan, Xiaona Chen, Hongchuan Jin, Xian Wang   +16 more
wiley   +1 more source

Lipid reprogramming and ferroptosis crosstalk in clear cell renal cell carcinoma: metabolic vulnerabilities and therapeutic targeting. [PDF]

Mol Cancer
Deng Q, Ji Y, Liu J, Wen T.
europepmc   +1 more source

Integrating Metabolic Modulation and Nanomedicine for Cancer Immunotherapy

Advanced Science, EarlyView.
Metabolic rewiring in cancer is mapped across glucose, amino acid, lipid, nucleotide, and mitochondrial pathways, with emphasis on immune regulation. The review integrates mechanisms linking these pathways to tumor progression and therapy resistance, and profiles nanomaterial platforms that both deliver therapeutics and actively reprogram ...
Xiaosu Zhou, Ruibing Deng, Zunde Liao, Xiaoyu Huang, Junting Huang, Hanlou Yang, Kam W. Leong, Yiling Zhong   +7 more
wiley   +1 more source

ATG7-induced autophagy inhibits ferroptosis and promotes the progression of colorectal adenocarcinoma. [PDF]

Discov Oncol
Chen M, Meng Z, Zhu L, Liu J.
europepmc   +1 more source

Construction and Validation of a Ferroptosis-related Prognostic Signature in Kidney Renal Clear Cell Carcinoma [PDF]

, 2020
Zhuolun Sun, Changying Jing, Chutian Xiao, Mingxiao Zhang, Zhenqing Wang, Mingzhao Li, Hua Wang   +6 more
openalex   +1 more source

Retromer Regulates Macro‐ and Micro‐Autophagy via Distinct Vacuolar Proteases in the Rice Blast Fungus

Advanced Science, EarlyView.
In wild‐type of M. oryzae (Guy11), MoPrb1 and MoPep4 are delivered into the vacuole by the retromer complex to mediate protein degradation and selective autophagy. Their proper localization and catalytic functions are essential for the fungal vegetative growth, conidiation and pathogenicity. However, retromer mutations disrupt this transport, impairing
Dingyang Zhang, Jiexiong Hu, Yonghe Hong, Yuping Fan, Minghui Peng, Yakubu Saddeeq Abubakar, Shujing Liang, Nan Jiang, Lili Lin, Xiaohong Pan, Huakun Zheng, Naweed I. Naqvi, Zonghua Wang, Wenhui Zheng   +13 more
wiley   +1 more source

Electroacupuncture attenuates intestinal epithelial ferroptosis in inflammatory bowel disease via Piezo1-mediated mitochondrial homeostasis. [PDF]

Chin Med
He H, Zhou J, Cao S, Liu W, Mei Z, Liu M.   +5 more
europepmc   +1 more source

Selenium Drives a Transcriptional Adaptive Program to Block Ferroptosis and Treat Stroke

, 2019
Ishraq Alim, Joseph T. Caulfield, Yingxin Chen, Vivek Swarup, Daniel H. Geschwind, Elena Ivanova, Javier Seravalli, Youxi Ai, Lauren Sansing, Emma J. Ste.Marie, Robert J. Hondal, Sushmita Mukherjee, John W. Cave, Botir T. Sagdullaev, Saravanan S. Karuppagounder, Rajiv R. Ratan   +15 more
openalex   +1 more source

Energy-stress-mediated AMPK activation inhibits ferroptosis

, 2020
Hyemin Lee, Fereshteh Zandkarimi, Yilei Zhang, Jitendra K. Meena, Jongchan Kim, Li Zhuang, Siddhartha Tyagi, Li Ma, Thomas F. Westbrook, Gregory R. Steinberg, Daisuke Nakada, Brent R. Stockwell, Boyi Gan   +12 more
openalex   +2 more sources