Results 301 to 310 of about 155,094 (383)

Modulation of Network Plasticity Opens Novel Therapeutic Possibilities in Cancer, Diabetes, and Neurodegeneration

Advanced Science, EarlyView.
Plasticity changes of molecular networks form a cellular learning process. Signaling network plasticity promotes cancer, metastasis, and drug resistance development. 55 plasticity‐related cancer drug targets are listed (20 having already approved drugs, 9 investigational drugs, and 26 being drug target candidates).
Márk Kerestély, István Narozsny, Levente Szarka, Daniel V. Veres, Peter Csermely, Dávid Keresztes   +5 more
wiley   +1 more source

Table 2_Anemoside B4 targets RAGE to attenuate ferroptosis in sepsis-induced acute lung injury.xlsx

Yue Bu (11357379), Zhixi Li (847419), Cheng Wang (102692), Yongjing Yu (13231173), Chang Liu (35901), Yue Sun (197395), Zhenyu Sun (1609570), Weidong Gong (13231176), Juan Luo (149338), Ziyong Yue (13231179)   +9 more
openalex   +1 more source

Role and mechanisms of ferroptosis in cognitive impairment: From molecular pathways to therapeutic targets (Review). [PDF]

Int J Mol Med
Ge S, Kong D, Fan S, Luo Y, Yin X, Jin Z, Xia W, Ma J.   +7 more
europepmc   +1 more source

Quantification of Single‐Cell Cysteine Using an Electrochemical Nanosensor for Predicting Tumor Disulfidptosis Susceptibility

Advanced Science, EarlyView.
Cysteine attracts interest due to its unique electrochemical activity and emerging relationship with disulfidptosis. This study develops a new electrochemical nanosensor, which represents the first of its kind capable of detecting intracellular cysteine for various types of tumor cells and primary tumor cells in mice to evaluate disulfidptosis ...
Congcong Zhang, Xiangdi Zhang, Shushen Li, Yuyang Li, Bei Yuan, Mingshuang Zheng, Shuo Zhang, Fangping Yuan, Min Jia, Lixia Lu, Jun Zhou, Zhenguo Zhang, Xin Du   +12 more
wiley   +1 more source

Iron entry in neurons and astrocytes: a link with synaptic activity [PDF]

, 2015
Daniele Zacchetti, Fabio Grohovaz, Franca Codazzi, Ilaria Pelizzoni   +3 more
core   +1 more source

PolarizationEngineering and Chemical Bond Reconstructionin Rare-Earth Hexagonal Manganite via Fe³⁺-Occupied B‑SiteDoping for Piezocatalytic Therapy and Ferroptosis

Meiqi Yang (4283371), Lu Yang (30847), Shili Gai (1467667), Meichen Li (8773820), Haijiang Gong (18529771), Ping’an Ma (1524742), Piaoping Yang (1467661)   +6 more
openalex   +1 more source

Targeting ferroptosis to overcome drug resistance in lung cancer. [PDF]

Transl Lung Cancer Res
Sheng P, Jin J, Liu H, Sun C, Chen Y, Chen X, Ma D, Shen J.   +7 more
europepmc   +1 more source

Lactylation Reprogramming in the Bone Infection Microenvironment Identifies PGK1 K361 as a Potential Therapeutic Target for Osteogenic Dysfunction

Advanced Science, EarlyView.
Staphylococcus aureus (S. aureus) infection creates a high‐lactate microenvironment, promoting p300‐mediated lactylation of PGK1 at lysine 361 (K361). Lactylated PGK1 translocates to the mitochondrial outer membrane and interacts with VDAC3. This interaction triggers FtMt downregulation, iron accumulation, and excessive PINK1/Parkin‐mediated mitophagy,
Han‐jun Qin, Si‐ying He, Ting‐hui Xiao, Da‐mao Dai, Xin‐jia Hu, Nan Jiang   +5 more
wiley   +1 more source

Protective Effects of Dexmedetomidine on Sepsis-Induced Vascular Leakage by Alleviating Ferroptosis via Regulating Metabolic Reprogramming

, 2021
She H, Hu Y, Y Zhou, Tan L, Yong‐Guan Zhu, Chao Ma, Yi‐Long Wu, W Chen, L Wang, Z Zhang, L Wang, Lei Liu, Li T   +12 more
openalex   +1 more source

Hepatic Hypoxia-Inducible Factor 1α Mediates Ferroptosis via Transferrin Receptor 1 in Acute Liver Injury. [PDF]

Antioxidants (Basel)
Yang J, Wang M, Cui S, Xia Y, Xie Y, Hu Z, Li N, Zhang X, Zhu P, Yu X, Wu L, Li J.   +11 more
europepmc   +1 more source