Results 301 to 310 of about 147,915 (338)

Neuroprotective Effect of Cannabidiol Against Rotenone in Hippocampal Neuron Culture

Chemistry – An Asian Journal, EarlyView.
(–)‐Cannabidiol (CBD) protects primary hippocampal neurons from rotenone, a mitochondrial complex I inhibitor that causes cell death. CBD preserves neuronal viability and morphology, with antagonist assays showing that transient receptor potential vanilloid 1 (TRPV1) mediates this neuroprotective effect.
Seoin Yang, Hyunwoo Choi, Jungnam Kim, Insung S. Choi   +3 more
wiley   +1 more source

Neutrophil extracellular traps aggravate blood-brain barrier disruption via ZBP1/FSP1-mediated ferroptosis after traumatic brain injury

Yanlin Zhu, Jianye Xu, Yan Chai, Peng Li, Liang Liu, Shu Zhang, Jianning Zhang, Xin Chen, Yanlin Zhu, Jianye Xu, Yan Chai, Peng Li, Liang Liu, Shu Zhang, Jianning Zhang, Xin Chen   +15 more
openalex   +1 more source

GDF10 Regulates Iron‐Dependent Lipid Oxidation in Colorectal Cancer Cells Through Interaction With IGF2

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Background: This study aims to identify genes with a high likelihood of genetic variation, significant expression differences, and prognostic implications in colorectal cancer (CRC) patients. The research also seeks to investigate the role and mechanisms of key genes in CRC through the analysis of health information data and a combination of ...
Kaobin Ouyang, Tianying Huang, Dan Xie, Hailin Xiong   +3 more
wiley   +1 more source

Icariin Inhibits Lung Adenocarcinoma Progression Through TP53-Mediated Ferroptosis. [PDF]

Onco Targets Ther
Jin Q, OuYang L, Li J, Yang X, Guo L.
europepmc   +1 more source

Enhanced Vatiquinone Bioavailability With Fatty Meals and Optimal Dosing Schedule

Biopharmaceutics &Drug Disposition, EarlyView.
This investigation discusses two clinical studies. One investigated the effect of fatty meals (≥ 25% fat) on vatiquinone PK exposures, and the other one characterized vatiquinone PK profiles when administered on a TID dosing regimen corresponding to mealtimes. The data support the recommendation of administering vatiquinone with fatty meals (≥ 25% fat)
Lucy Lee, Katsuyuki Murase, Martin Thoolen, Peter Giannousis, Diksha Kaushik, Lee Golden, Ronald Kong   +6 more
wiley   +1 more source

X‐ray controlled release strategy in cancer therapy

BMEMat, EarlyView.
A comprehensive review on the design principles and current strategies of X‐ray stimulated release systems in cancer therapy, focusing on the X‐ray responsive functional groups and materials as well as discussing the advantages and current challenges of X‐ray controlled release systems in cancer therapy.
Yiling Ruan, Hongxiang Huang, Huihui Liu, Jinglang Gong, Changjun Li, Xiaolian Sun   +5 more
wiley   +1 more source

Maternal sleep deprivation during pregnancy induced offspring germ cells loss through ferroptosis. [PDF]

Cell Death Discov
Liu Q, Yan J, Wang H, Wang T, Zhang K, Li A, Wang J, Zhang T, Shen W, Li L.   +9 more
europepmc   +1 more source

The effect of sodium nitroprusside in scaffolds for synergetic gas‐photothermal therapy of osteosarcoma

BMEMat, EarlyView.
The PCLA‐SNP scaffolds can produce photothermal agents in situ under ultraviolet radiation. Then, the scaffold can release nitric oxide gas spontaneously and generate hyperthermia under near‐infrared laser to enhance ablation of bone tumors. Furthermore, the calcium and iron ions released from PCLA‐SNP scaffolds can accelerate bone regeneration ...
Shaojie Dong, Yuwei Zhang, Yukun Mei, Changjie Sun, Xingge Yu, Mazaher Gholipourmalekabadi, Kaili Lin, Lin Niu, Li Zhao, Changyong Yuan   +9 more
wiley   +1 more source

Ferroptosis in Oral Cancer: Mechanistic Insights and Clinical Prospects. [PDF]

Cells
Lee J, Roh JL.
europepmc   +1 more source

Ursolic acid inhibits the proliferation of triple‑negative breast cancer stem‑like cells through NRF2‑mediated ferroptosis

Xinhua Yang, Beibei Liang, Lisha Zhang, Mingzhu Zhang, Ming Ma, Lijuan Qing, Hao Yang, Gang Huang, Jian Zhao   +8 more
openalex   +2 more sources