Results 331 to 340 of about 109,999 (379)

A Mesoporous Calcium Peroxide Nanocuboid with High Tumor Accumulation Across Biological Barriers for High Efficacy Tumor Therapy

Advanced Science, EarlyView.
The ferroheme (FH) and exceedingly small magnetic iron oxide nanoparticles (IO) loaded mesoporous calcium peroxide nanocuboid (MCPNC) with conjugation of hyaluronic acid (HA) possesses exceptional capability of tumor accumulation, and enhances therapeutic efficacy of tumors based on the mechanism of promoting a positive feedback loop of Fenton reaction
Qingdeng Fan, Min Wang, Jie Lin, Ya Huang, Jing Yang, Jiaoyang Zhu, Bin Ren, Li Sun, Zongheng Li, Aochi Liu, Wei Xiong, Zhenni Wei, Lin Huang, Chenggong Yan, Ge Wen, Zhao Chen, Xiaoyuan Chen, Zheyu Shen   +17 more
wiley   +1 more source

Ferroptosis in the U87MG Human Glioblastoma Cell Line Induces Damage Associated Molecular Phenotypes. [PDF]

MicroPubl Biol
Neitzel L, Rea S, Cornell J, Williams C, Hong C.   +4 more
europepmc   +1 more source

Harnessing the Biological Responses Induced by Nanomaterials for Enhanced Cancer Therapy

Aggregate, EarlyView.
Nanomaterial (NM)‐induced toxicity can be strategically repurposed for cancer therapy. This review summarizes the mechanism by which NMs selectively activate specific cellular processes to regulate cell fate independently. We also discussed how NMs‐induced biological responses can be leveraged as therapeutic strategies for cancer treatment.
Liting Wang, Hao Fu, Jiangtao Lin, Meng Zhao, Chuanrong Chen, Hongze Liao, Yourong Duan   +6 more
wiley   +1 more source

Inhibitory effects of herbal monomers on ferroptosis in renal fibrosis: a review and mechanistic study. [PDF]

Front Pharmacol
Liu K, Yu M, He Y, Wang T, Li G, Wang L, Zhong X.   +6 more
europepmc   +1 more source

Supramolecular Probe for Monitoring Lysosomal Ferritinophagy to Facilitate the Early Diagnosis of Parkinson's Disease

Aggregate, EarlyView.
A supramolecular fluorescent probe, TPE‐4B/4Q[7], was designed to target lysosomes. The restriction of intramolecular rotation effect mediated by Q[7] enhances the fluorescence of TPE‐4B/4Q[7], enabling selective detection of Fe3+ with a detection limit of 1.23 × 10⁻⁶ M.
Shiqin Zhou, Bo Xiao, Jiamin Chen, Jinming Zhu, Xia Ran, Zuoji Liu, Chaozhong Li, Li Wang, Xinai Cui, Rong Li, Guangwei Feng, Jian Feng   +11 more
wiley   +1 more source

The role of hydroxyindoles in protecting neuronal cultures from ferroptosis. [PDF]

Cell Death Discov
Jakaria M, Cannon JR.
europepmc   +1 more source

Brassinin from Brassica campestris L. inhibits colorectal cancer by inducing p62/NRF2/GPX4‐regulated ferroptosis

Animal Models and Experimental Medicine, EarlyView.
BSN suppresses the cell viability of colorectal cancer by inducing GPX4‐regulated ferroptosis. BSN may bind to NRF2 protein to inactivate the NRF2 signaling, inhibiting the expression of p62 and HO‐1. Abstract Background Indole phytoalexins, plant‐derived compounds present in cruciferous vegetables, have demonstrated anticancer properties.
Shi‐Yuan Wen, Rui‐Rui Gao, Yan‐Yan Chen, Yi‐Jie Wang, Xin‐Tong Wang, Hai‐Xin Liu   +5 more
wiley   +1 more source

Ferroptosis: a double-edged sword that enhances radiation sensitivity and facilitates radiation-induced injury in tumors. [PDF]

Front Immunol
Liu Y, Zhan J, Wang J, Zeng X, Liu S, Huang L, Niu L, Sun C, Ding Z, Xing Y, Zhou Z, Li X, Li Q, Wang H.   +13 more
europepmc   +1 more source

Identification of ferroptosis‐related genes involved in chronic obstructive pulmonary disease based on bioinformatics analysis

Animal Models and Experimental Medicine, EarlyView.
The design of the entire paper. Green part represents the bioinformatics analysis approach. Yellow part represents the ideas of animal experiment. Abstract Background Chronic obstructive pulmonary disease (COPD) is a type of chronic respiratory disease.
Xuejing Luan, Jinghui Xie, Lu Zhang, Xiao Ma, Lichangtian Jiao, Jie Zhu   +5 more
wiley   +1 more source

Long non-coding RNA NORAD serves as a promoter of oncogenesis and inhibits ferroptosis via miR-144-3p-mTOR-ferritinophagy axis in cancer. [PDF]

Eur J Med Res
Zhang X, Zheng W, Li H, Zhang L, Zhao H, Sui S, Cheng W.   +6 more
europepmc   +1 more source