Results 61 to 70 of about 72,927 (343)
A cell-permeable biscyclooctyne as a novel probe for the identification of protein sulfenic acids [PDF]
, 2016 Reactive oxygen species act as important second messengers in cell signaling and homeostasis through the oxidation of protein thiols. However, the dynamic nature of protein oxidation and the lack of sensitivity of existing molecular probes have hindered ...
Hartley, Richard C. +4 more
core +2 more sources
Ferritinophagy and ferroptosis in the management of metabolic diseases [PDF]
, 2021 Ferroptosis is a form of regulated cell death modality associated with disturbed iron-homeostasis and unrestricted lipid peroxidation. Ample evidence has depicted an essential role for ferroptosis as either the cause or consequence for human diseases ...
Ajoolabady, Amir +12 more
core +1 more source
Frontiers in Molecular Biosciences, 2022 Objective: Ferroptosis is a type of cell death involved in various human diseases, including nerve injury. However, the role of ferroptosis in lumbosacral spinal root avulsion (LSRA) remains unknown.
Zhibin Zhou, Jiajia Lu, Jun Ma, Lei Zhu
doaj +1 more source
The Potential of Ferroptosis-Targeting Therapies for Alzheimer's Disease:From Mechanism to Transcriptomic Analysis [PDF]
, 2021 Alzheimer’s disease (AD), the most common form of dementia, currently affects 40–50 million people worldwide. Despite the extensive research into amyloid β (Aβ) deposition and tau protein hyperphosphorylation (p-tau), an effective treatment to stop or ...
den Dunnen, Wilfred F A +2 more
core +1 more source
Ferroptosis and kidney disease
Nefrología (English Edition), 2020 Cell death is a finely regulated process occurring through different pathways. Regulated cell death, either through apoptosis or regulated necrosis offers the possibility of therapeutic intervention. Necroptosis and ferroptosis are among the best studied forms of regulated necrosis in the context of kidney disease.
Alberto Ortiz +8 more
openaire +4 more sources
Zinc transporter ZIP7 is a novel determinant of ferroptosis
Cell Death and Disease, 2021 Ferroptosis is a newly described form of regulated cell death triggered by oxidative stresses and characterized by extensive lipid peroxidation and membrane damages.
Po-Han Chen +7 more
doaj +1 more source
The role of microRNAs in ferroptosis
Frontiers in Molecular Biosciences, 2022 Ferroptosis is a newly discovered type of programmed cell death, which is closely related to the imbalance of iron metabolism and oxidative stress. Ferroptosis has become an important research topic in the fields of cardiomyopathy, tumors, neuronal injury disorders, and ischemia perfusion disorders.
Liqing Guo +3 more
openaire +3 more sources
Cell Death Discovery, 2023 Alcohol abuse is a significant cause of global morbidity and mortality, with alcoholic liver disease (ALD) being a common consequence. The pathogenesis of ALD involves various cellular processes, including oxidative stress, inflammation, and hepatic cell
Jiao Luo +10 more
doaj +1 more source
Characterizing Ferroptosis in the Model Invertebrate Hydra Vulgaris [PDF]
, 2022 Ferroptosis is a form of regulated cell death distinct from apoptosis. It occurs in diverse animals and in plants, but has not been documented in Hydra vulgaris, a cnidarian species used for studies of stem cell biology and regeneration.
Ott, Darci
core +1 more source
Ferroptosis assassinates tumor
Journal of Nanobiotechnology, 2022 AbstractIn 2020, nearly 20 million peoples got cancer and nearly 10 million peoples died of cancer, indicating the cancer remains a great threat to human health and life. New therapies are still in urgent demand. We here develop a novel cancer therapy named Ferroptosis ASsassinates Tumor (FAST) by combining iron oxide nanoparticles with cancer ...
Tao Luo, Yile Wang, Jinke Wang
openaire +3 more sources