Results 101 to 110 of about 143,465 (317)
Long‐Term Active Rather than Passive Restoration Promotes Soil Organic Carbon Accumulation by Alleviating Microbial Nitrogen Limitation in an Extremely Degraded Alpine Grassland
Advanced Science, EarlyView.Active restoration increases soil organic carbon stocks by reducing microbial nitrogen limitation. Nitrogen availability promotes particulate to mineral‐associated organic carbon conversion by reducing microbial carbon use efficiency. Passive restoration has no effect on soil organic carbon stocks.Jinchao Gong, Feida Sun, Jingjing Wu, Shijie Zhou, Yue Xiu, Linlin Li, Tahmina Kausar, Zhouwen Ma, Jiqiong Zhou, Lin Liu, Yongxing Cui, Jordi Sardans, Josep Peñuelas, Ahmed Elrys, Ji Chen, Yanfu Bai +15 morewiley +1 more sourcePubertal low dose exposure to benzophenone-3 (BP-3) alters murine mammary stem cell functions
Ecotoxicology and Environmental SafetyBenzophenone-3 (BP-3) is an organic UV filter that is widely used in personal care products and has been indicated to have negative impacts on the environment and human health.Hui Gao, Xintong Yang, Pengge Pan, Xueli Liu, Yan Ma, Yadan Chen, Yunxin Liu, Yaqi Sun, Sinan Cao, Yuan Tian, Yanzhou Yang +10 moredoaj +1 more sourceA Biomarker‐Driven Ovary–Endometrium Organ‐on‐a‐Chip Mimicking 3D Multicellular Complexity and Menstrual Cyclicity for Predicting Reproductive Toxicity
Advanced Science, EarlyView.We present a dual‐organ, biomarker‐integrated ovaryendometrium organ‐on‐a‐chip that recapitulates 3D tissue complexity, menstrual cycle dynamics, and hormonal crosstalk. This platform enables real‐time, cell‐typespecific fluorescent readouts of reproductive toxicity using ANGPTL4 and SERPINB2 as early‐response reporters.Soo‐Rim Kim, Eun‐kyung Min, Choon‐Mi Lee, Chan Hum Park, Byung‐Chul Oh, YunJae Jung, In‐Sun Hong +6 morewiley +1 more sourceThe Mitochondrial Guardian α‐Amyrin Mitigates Alzheimer's Disease Pathology via Modulation of the DLK‐SARM1‐ULK1 Axis
Advanced Science, EarlyView.Dietary habits play a key role in chronic diseases, and higher annual consumption of fruit and vegetable may lower risk of dementia. Artificial intelligence predicts the lipid‐like compound α‐Amyrin (αA) from plants with edible peels as a drug candidate against Alzheimer's disease.Shu‐Qin Cao, Juan Ignacio Jiménez‐Loygorri, Yunguang Qiu, You Jung Kang, Khanh Van Do, Annabel E. Smith, Junjie Huang, Jun‐ping Pan, Lipeng Mao, Ang Li, Hangge Yang, Yahyah Aman, Maria Jose Donate Lagartos, Sofie Hindkjær Lautrup, Anbin Chen, Kristina Xiao Liang, Hailong Zhang, Juan Yi, Xurui Jin, Tin Cho Cheung, Olympia Apokotou, Florentia Papastefanaki, Rebecca Matsas, William A. McEwan, Feixiong Cheng, Hansang Cho, Guobing Chen, Huanxing Su, Konstantinos Palikaras, Oscar Junhong Luo, Qian Hua Zhao, Ding Ding, Cornelia van Duijn, Nektarios Tavernarakis, Patricia Boya, Tewin Tencomnao, Evandro F. Fang +36 morewiley +1 more sourceComparative effects of streptozotocin, dehydroepiandrosterone and letrozole with high fat diet on ovarian injury induction and functional impairment
Scientific ReportsThis study investigates the mechanisms by which environmental factors affect ovarian function. Environmental toxins and unhealthy lifestyles adversely affect women’s health, primarily impair ovarian function. Environmental toxins and unhealthy lifestyles Leyi Yu, Qingjie Peng, Cunling Ma, Jiahui Ouyang, Hongru Ma, Shuzhe Fan, Miao Sun, Huiming Ma, Xiaoli Du, Xiangdong Zhu, Guangyong Li, Rui He +11 moredoaj +1 more sourceNap1L4a Cooperates with Scl/Klf1 to Recruit H2A.Z in Mediating Interactions Among Cis‐Regulatory Elements and Transcription Required for Primitive Erythropoiesis in Zebrafish
Advanced Science, EarlyView.Nap1l4a is required in erythropoiesis and hypoxia responses via physical interaction with Klf1 and Scl to recruit the histone variant H2A.Z. This facilitates its associated cis‐regulatory element (CRE) remodeling and the consequent chromatin assembly, and activates the transcription of erythroid lineage‐specific genes.JiaHao Shi, FuMing Lai, Zheng Shen, XiaoYan Zhang, HanFei Wang, WenYe Liu, YunLong Wang, KuanYu Li, GuoLiang Li, YaPing Fang, Jing‐Xia Liu +10 morewiley +1 more sourceStudy on Hepatotoxicity of Benzophenone-3 at Environmental Concentration in Postpartum Mice
ToxicsBenzophenone-3 (BP-3), a widely used ultraviolet absorber in various scenarios, exhibits estrogenic toxicity at environmental concentrations—as demonstrated in our prior work.Huai-Fan Zhai, Ya-Nan Tian, Yu-Xin Sheng, Ya-Jia Pu, Yan-Rong Gao, Jia-Yi Chen, Jia-Di Liu, Jia Ma, Hai-Ming Xu, Peng-Bin Yang, Hong-Mei Li +10 moredoaj +1 more sourceSurvey of Third-Party Parenting Options Associated With Fertility Preservation Available to Patients With Cancer Around the Globe [PDF]
, 2017 Purpose: In the accompanying article, “Analysis of Fertility Preservation Options Available to Patients With Cancer Around the Globe,” we showed that specific fertility preservation services may not be offered at various sites around the world because of Adiga, Satish Kumar, Almeida-Santos, Teresa, Anazodo, Antoinette, Andersen, Claus Yding, Anderson, Richard A., Antunes, Roberto de A., Arvas, Ayse, Ataman, Lauren M., Azambuja, Ricardo, Azmy, Osama, Beerendonk, Catharina C.M., Bourlon, Maria T., Campos-Junior, Paulo Henrique Almeida, Chehin, Maurício Barbour, de Roo, Saskia F., De Vos, Michel, del Mar Andrés, María, Diaz-Garcia, Cesar, Edmonds, Maxwell E., Fathi, Rouhollah, Ferreira Melo e Silva, Lígia Helena, Fontoura, Paula, Furui, Tatsuro, Greenblatt, Ellen M., Grieco, Silvana Chedid, Horbaczewska, Anna, Jach, Robert, Jayasinghe, Yasmin, Khrouf, Mohamed, Kim, Seok Hyun, Lee, Jung Ryeol, Mallmann, Peter, Marcos de Meneses e Silva, Joao, Marinho, Ricardo M., Medrano, Jose, Melo, Cláudia, Mitchell, Rod, Motta, Eduardo, Nelen, Willianne, Ramalho de Carvalho, Bruno, Rashedi, Alexandra S., Reis, Fernando M., Rodrigues, Jhenifer K., Romero, Sergio, Salama, Mahmoud, Sartorio, Cassio, Scarella, Anibal, Shaulov, Talya, Silva, Adelino Amaral, Smith, Kristin, Smitz, Johan, Sugishita, Yodo, Suh, Chang Suk, Suzuki, Nao, Sánchez, Flor, Takae, Seido, Terrado, Guillermo, Van Moer, Ellen, Vega, Mario, Wildt, Ludwig, Winkler-Crepaz, Katharina, Woodruff, Teresa K., Zand, Elnaz +62 morecore +3 more sources