Results 51 to 60 of about 9,350 (117)

Identification of cryosensitive niches and a targetable FOS/AP‑1 program in the human ovarian cortex by single‑cell and spatial transcriptomics

BMC Medicine
Background The ovary is a vital and dynamic reproductive organ. Ovarian tissue cryopreservation (OTC) plays a vital role in preserving female fertility. However, the cellular subtypes most susceptible to cryoinjury and the molecular mechanisms underlying
Fanghao Guo, Di Sun, Haixia Ding, Yanquan Li, Baicai Yang, Mengxi Guo, Yongjian Ma, Rui Qiao, Songmao Li, Li Zhang, Qing Zhang, Meiling Zhang, Wen Li   +12 more
doaj   +1 more source

Fertility preservation during cancer treatment: clinical guidelines

, 2014
Kenny A Rodriguez-Wallberg,1,2 Kutluk Oktay3,4 1Karolinska Institutet, Department of Clinical Science, Intervention and Technology, Division of Obstetrics and Gynecology, 2Reproductive Medicine, Karolinska University Hospital Huddinge, Stockholm, Sweden;
Rodriguez-Wallberg KA, Oktay K
core  

Experience of fertility preservation among younger people diagnosed with cancer

, 2010
Of the 293,600 cancers diagnosed annually in the UK, 11% occur in the 15- to 49-year age group. Fertility preservation options exist for those faced with the loss of fertility as a consequence of radiotherapy or chemotherapy. The aim of this study was to
Rubin, G, Stewart, J, Wilkes, S, Crosland, A, Coulson, S   +4 more
core   +1 more source

Fertility preservation for medical reasons in girls and women: British fertility society policy and practice guideline. [PDF]

, 2018
Fertility preservation in the female poses several challenges due to the invasive nature of the techniques available to achieve it. The guideline aims to bring together the evidence available for the measures for fertility preservation and their outcome.
Raj Mathur, Davies, MC, Richard A. Anderson, Webber, L, Georgina L. Jones, Yasmin, E, Jones, GL, Mathur, R, Ephia Yasmin, Lane, S, British Fertility Society, Neerujah Balachandren, Sheila Lane, Balachandren, N, Lisa Webber, Anderson, RA, Melanie C. Davies   +16 more
core   +1 more source

Lycium barbarum Polysaccharide Improves Iron Homeostasis in Spermatocytes and Sertoli Cells via NRF2 to Alleviate DEHP-Induced Male Reproductive Toxicity in Mice

Toxics
Male infertility, as a globally significant reproductive health issue, remains idiopathic in over 40% of cases. Reproductive disorders in males induced by environmental pollutants, such as di(2-ethylhexyl) phthalate (DEHP), have garnered considerable ...
Zhen Zhang, Yitong Shang, Hong Yang, Liyang Ding, Yu Deng, Bo Xu, Xufeng Fu   +6 more
doaj   +1 more source

Relative safety of various spermatogenic stem cell purification methods for application in spermatogenic stem cell transplantation

Stem Cell Research & Therapy, 2019
Background Spermatogonial stem cell (SSC) transplantation technology as a promising option for male fertility preservation has received increasing attention, along with efficient SSC purification technology as a necessary technical support; however, the ...
Jia Tian, Ke Ma, Cheng-bin Pei, Shao-hua Zhang, Xue Li, Yue Zhou, Bei Yan, Hong-yan Wang, Liang-hong Ma   +8 more
doaj   +1 more source

The Protective Effect and Molecular Mechanism of Tetrandrine on Male Reproductive Damage Caused by Silicon Dioxide

Toxics
The long-term inhalation of free silica dust causes silicosis—a prevalent occupational hazard—yet its systemic effect on male reproductive toxicity remains underexplored.
Hong-Mei Li, Xiao-Qi Zeng, Qing Chang, Yu-Xin Sheng, Ya-Jia Pu, Yi Wang, Bin Cheng, Hong-Hui Li, Jie Xuan, Ling Zhang, Hai-Ming Xu   +10 more
doaj   +1 more source

Harnessing extracellular vesicles from adipose-derived stem cells for the treatment of 4-vinylcyclohexene diepoxide-induced premature ovarian insufficiency

Stem Cell Research & Therapy
Background Premature ovarian insufficiency (POI) is a challenging condition with limited effective treatments. Adipose-derived stem cells (ADSCs) have demonstrated potential in tissue repair, and their extracellular vesicles (ADSC-EVs) show more safety ...
Yanquan Li, Feng Chen, Wei Zhao, Di Sun, Li Zhang, Rui Qiao, Qianhui Hu, Songmao Li, Boyuan Chen, Haixia Ding, Meiling Zhang, Qing Zhang, Fanghao Guo, Wen Li   +13 more
doaj   +1 more source

Asthma and Infertility: A Prospective Case–Control Study on Pregnancy and Live Birth Rates in Women With Asthma Undergoing Assisted Reproduction

The Clinical Respiratory Journal
Background Previous studies have suggested a negative impact of asthma on fertility, and it has been hypothesized that the underlying inflammation is playing an important role.
Frida E. Lundberg, Amalie H. Sneckenborg, Hanna Nilsson, Kenny A. Rodriguez‐Wallberg   +3 more
doaj   +1 more source

The male reproductive toxicity after 5-Fluorouracil exposure: DNA damage, oxidative stress, and mitochondrial dysfunction in vitro and in vivo

Ecotoxicology and Environmental Safety
5-Fluorouracil (5-FU), a chemotherapeutic drug used to treat a variety of cancers, can enter the environment through different routes, causing serious public health and environmental concerns.
Wenzheng Yuan, Guojie Ji, Xiaowei Shi, Zhibin Sun, Chenyan Liu, Yangyang Yu, Wenmi Li, Xiaoyi Wang, Huanhuan Hu   +8 more
doaj   +1 more source